| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the tolazoline-1918 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADCY9 | adenylate cyclase 9 |
| AEN | apoptosis enhancing nuclease |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ASXL1 | additional sex combs like transcriptional regulator 1 |
| BAG5 | BCL2-associated athanogene 5 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL7B | B-cell CLL/lymphoma 7B |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDK13 | cyclin-dependent kinase 13 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CNPY3 | canopy FGF signaling regulator 3 |
| COL13A1 | collagen, type XIII, alpha 1 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CST4 | cystatin S |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNASE2 | deoxyribonuclease II, lysosomal |
| DXO | decapping exoribonuclease |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FAM65A | family with sequence similarity 65, member A |
| FNBP1 | formin binding protein 1 |
| FZD8 | frizzled class receptor 8 |
| GAMT | guanidinoacetate N-methyltransferase |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLRX3 | glutaredoxin 3 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GRK6 | G protein-coupled receptor kinase 6 |
| HBP1 | HMG-box transcription factor 1 |
| HDAC5 | histone deacetylase 5 |
| HDAC7 | histone deacetylase 7 |
| HIST1H3G | histone cluster 1, H3g |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HK2 | hexokinase 2 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXB13 | homeobox B13 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| LAD1 | ladinin 1 |
| LDLR | low density lipoprotein receptor |
| LRRC61 | leucine rich repeat containing 61 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like |
| MAPK7 | mitogen-activated protein kinase 7 |
| NPAS2 | neuronal PAS domain protein 2 |
| NRBP1 | nuclear receptor binding protein 1 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 |
| ORC1 | origin recognition complex, subunit 1 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PIDD1 | p53-induced death domain protein 1 |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PRPF6 | pre-mRNA processing factor 6 |
| PRRC2B | proline-rich coiled-coil 2B |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RAB15 | RAB15, member RAS oncogene family |
| RAB31 | RAB31, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RAD50 | RAD50 homolog (S. cerevisiae) |
| RARG | retinoic acid receptor, gamma |
| RECQL5 | RecQ protein-like 5 |
| RHOQ | ras homolog family member Q |
| RNF113A | ring finger protein 113A |
| RNPS1 | RNA binding protein S1, serine-rich domain |
| RPS2 | ribosomal protein S2 |
| SFTPB | surfactant protein B |
| SH2D3A | SH2 domain containing 3A |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SHFM1 | split hand/foot malformation (ectrodactyly) type 1 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SVIL | supervillin |
| TMEM8A | transmembrane protein 8A |
| TSC2 | tuberous sclerosis 2 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| USE1 | unconventional SNARE in the ER 1 homolog (S. cerevisiae) |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| WDR74 | WD repeat domain 74 |
| ZNF426 | zinc finger protein 426 |
| ZNF552 | zinc finger protein 552 |
| ZNF576 | zinc finger protein 576 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| AATF | apoptosis antagonizing transcription factor |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ACVR1 | activin A receptor, type I |
| ALDOC | aldolase C, fructose-bisphosphate |
| ANKRD10 | ankyrin repeat domain 10 |
| ARMC6 | armadillo repeat containing 6 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CASZ1 | castor zinc finger 1 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CNTNAP1 | contactin associated protein 1 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTAGE9 | CTAGE family, member 9 |
| DCLRE1B | DNA cross-link repair 1B |
| DENND4B | DENN/MADD domain containing 4B |
| DESI1 | desumoylating isopeptidase 1 |
| DIXDC1 | DIX domain containing 1 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DOCK1 | dedicator of cytokinesis 1 |
| EXOC5 | exocyst complex component 5 |
| FAM50B | family with sequence similarity 50, member B |
| FAM53B | family with sequence similarity 53, member B |
| FMO4 | flavin containing monooxygenase 4 |
| GALR3 | galanin receptor 3 |
| GCC2 | GRIP and coiled-coil domain containing 2 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GOLGA8B | golgin A8 family, member B |
| GPR12 | G protein-coupled receptor 12 |
| GPR27 | G protein-coupled receptor 27 |
| GRPR | gastrin-releasing peptide receptor |
| GSTZ1 | glutathione S-transferase zeta 1 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HOXA5 | homeobox A5 |
| HS1BP3 | HCLS1 binding protein 3 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFNA17 | interferon, alpha 17 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| KAT2A | K(lysine) acetyltransferase 2A |
| KAT2B | K(lysine) acetyltransferase 2B |
| KIAA1551 | KIAA1551 |
| KIF13B | kinesin family member 13B |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MED4 | mediator complex subunit 4 |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NFS1 | NFS1 cysteine desulfurase |
| NLRX1 | NLR family member X1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NSUN3 | NOP2/Sun domain family, member 3 |
| OXCT1 | 3-oxoacid CoA transferase 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RAB36 | RAB36, member RAS oncogene family |
| RCOR3 | REST corepressor 3 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RMI1 | RecQ mediated genome instability 1 |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| SATB1 | SATB homeobox 1 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TDRD7 | tudor domain containing 7 |
| TEFM | transcription elongation factor, mitochondrial |
| TGFBR3 | transforming growth factor, beta receptor III |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TRIM5 | tripartite motif containing 5 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| UBA5 | ubiquitin-like modifier activating enzyme 5 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBP1 | upstream binding protein 1 (LBP-1a) |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF32 | zinc finger protein 32 |
