| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tolazoline-4262 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
| ABO | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AGXT | alanine-glyoxylate aminotransferase |
| AQP6 | aquaporin 6, kidney specific |
| B3GALT2 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C8A | complement component 8, alpha polypeptide |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CCDC170 | coiled-coil domain containing 170 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD28 | CD28 molecule |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| COL1A2 | collagen, type I, alpha 2 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DOCK3 | dedicator of cytokinesis 3 |
| DOK2 | docking protein 2, 56kDa |
| DST | dystonin |
| EBF2 | early B-cell factor 2 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| FAM134B | family with sequence similarity 134, member B |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FCAR | Fc fragment of IgA receptor |
| FGFR3 | fibroblast growth factor receptor 3 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HCRTR1 | hypocretin (orexin) receptor 1 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| ID2B | inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene) |
| IDS | iduronate 2-sulfatase |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL1RN | interleukin 1 receptor antagonist |
| IL5RA | interleukin 5 receptor, alpha |
| INS | insulin |
| IQCC | IQ motif containing C |
| ITIH4 | inter-alpha-trypsin inhibitor heavy chain family, member 4 |
| IZUMO4 | IZUMO family member 4 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KRT20 | keratin 20, type I |
| KSR1 | kinase suppressor of ras 1 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOXL3 | lysyl oxidase-like 3 |
| LRRC75B | leucine rich repeat containing 75B |
| LRRN2 | leucine rich repeat neuronal 2 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MIR622 | microRNA 622 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYH13 | myosin, heavy chain 13, skeletal muscle |
| NEK9 | NIMA-related kinase 9 |
| NME8 | NME/NM23 family member 8 |
| NPR1 | natriuretic peptide receptor 1 |
| NRG2 | neuregulin 2 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OLFM4 | olfactomedin 4 |
| ORM1 | orosomucoid 1 |
| OSBPL7 | oxysterol binding protein-like 7 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| POU6F1 | POU class 6 homeobox 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PRDM14 | PR domain containing 14 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RAB40C | RAB40C, member RAS oncogene family |
| RBM12B | RNA binding motif protein 12B |
| RDH8 | retinol dehydrogenase 8 (all-trans) |
| RHO | rhodopsin |
| RIC3 | RIC3 acetylcholine receptor chaperone |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SH2D3C | SH2 domain containing 3C |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STOM | stomatin |
| SYT5 | synaptotagmin V |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TRIM10 | tripartite motif containing 10 |
| TRIM3 | tripartite motif containing 3 |
| TRIM31 | tripartite motif containing 31 |
| TRMT1 | tRNA methyltransferase 1 homolog (S. cerevisiae) |
| TRO | trophinin |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 |
| VNN1 | vanin 1 |
| ZNF223 | zinc finger protein 223 |
| ZNF407 | zinc finger protein 407 |
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| BEX1 | brain expressed, X-linked 1 |
| BNC1 | basonuclin 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CEP112 | centrosomal protein 112kDa |
| CEP162 | centrosomal protein 162kDa |
| CEP295 | centrosomal protein 295kDa |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CHMP6 | charged multivesicular body protein 6 |
| CLDN15 | claudin 15 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DFNB31 | deafness, autosomal recessive 31 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| EFNA3 | ephrin-A3 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ETNK2 | ethanolamine kinase 2 |
| FAM169A | family with sequence similarity 169, member A |
| FAM184A | family with sequence similarity 184, member A |
| FAM69A | family with sequence similarity 69, member A |
| FAT4 | FAT atypical cadherin 4 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GID4 | GID complex subunit 4 |
| GLI3 | GLI family zinc finger 3 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| H2AFJ | H2A histone family, member J |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXA1 | homeobox A1 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| INCENP | inner centromere protein antigens 135/155kDa |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| ITK | IL2-inducible T-cell kinase |
| KIAA1644 | KIAA1644 |
| KRT86 | keratin 86, type II |
| LIFR | leukemia inhibitory factor receptor alpha |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| MCC | mutated in colorectal cancers |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MLYCD | malonyl-CoA decarboxylase |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| NDP | Norrie disease (pseudoglioma) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PALMD | palmdelphin |
| PDE8B | phosphodiesterase 8B |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLCD1 | phospholipase C, delta 1 |
| PRPH | peripherin |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RPAIN | RPA interacting protein |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCG5 | secretogranin V |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SHROOM2 | shroom family member 2 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SPRYD7 | SPRY domain containing 7 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TAGLN3 | transgelin 3 |
| TEX40 | testis expressed 40 |
| THBS3 | thrombospondin 3 |
| TMEM132A | transmembrane protein 132A |
| TMEM160 | transmembrane protein 160 |
| TMEM242 | transmembrane protein 242 |
| TMEM53 | transmembrane protein 53 |
| TSPAN8 | tetraspanin 8 |
| TXLNG | taxilin gamma |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF227 | zinc finger protein 227 |
| ZNF254 | zinc finger protein 254 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF492 | zinc finger protein 492 |
| ZNF778 | zinc finger protein 778 |
