| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the tolazoline-4844 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADAMTS20 | ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| APOM | apolipoprotein M |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ATXN2L | ataxin 2-like |
| BDKRB2 | bradykinin receptor B2 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CHRNB4 | cholinergic receptor, nicotinic, beta 4 (neuronal) |
| CLTB | clathrin, light chain B |
| COL1A1 | collagen, type I, alpha 1 |
| CRYGC | crystallin, gamma C |
| CTSZ | cathepsin Z |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOCK6 | dedicator of cytokinesis 6 |
| DOCK9 | dedicator of cytokinesis 9 |
| DRD2 | dopamine receptor D2 |
| DSPP | dentin sialophosphoprotein |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| FGF6 | fibroblast growth factor 6 |
| FTO | fat mass and obesity associated |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GIPR | gastric inhibitory polypeptide receptor |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPATCH2L | G patch domain containing 2-like |
| GPM6A | glycoprotein M6A |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| HAMP | hepcidin antimicrobial peptide |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HFE | hemochromatosis |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFNA14 | interferon, alpha 14 |
| IGLV3-19 | immunoglobulin lambda variable 3-19 |
| IL4R | interleukin 4 receptor |
| IL9R | interleukin 9 receptor |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIAA0754 | KIAA0754 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL3 | kelch-like family member 3 |
| LAMA4 | laminin, alpha 4 |
| LHX1 | LIM homeobox 1 |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| MAGEH1 | melanoma antigen family H1 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MMP25 | matrix metallopeptidase 25 |
| MMP3 | matrix metallopeptidase 3 |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MT4 | metallothionein 4 |
| NEB | nebulin |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NRP2 | neuropilin 2 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPIAL4A | peptidylprolyl isomerase A (cyclophilin A)-like 4A |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RIF1 | replication timing regulatory factor 1 |
| RTN2 | reticulon 2 |
| S100A8 | S100 calcium binding protein A8 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SH3BP2 | SH3-domain binding protein 2 |
| ST7 | suppression of tumorigenicity 7 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| SYNPO | synaptopodin |
| TBKBP1 | TBK1 binding protein 1 |
| TBX21 | T-box 21 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| WSCD1 | WSC domain containing 1 |
| YIPF4 | Yip1 domain family, member 4 |
| YOD1 | YOD1 deubiquitinase |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF230 | zinc finger protein 230 |
| ZNF280A | zinc finger protein 280A |
| Symbol | Name |
|---|---|
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AKIRIN1 | akirin 1 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANKRD36 | ankyrin repeat domain 36 |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CA11 | carbonic anhydrase XI |
| CCDC186 | coiled-coil domain containing 186 |
| CCDC85C | coiled-coil domain containing 85C |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CENPJ | centromere protein J |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CIC | capicua transcriptional repressor |
| CISH | cytokine inducible SH2-containing protein |
| CSTA | cystatin A (stefin A) |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP2 | dual specificity phosphatase 2 |
| EXOC5 | exocyst complex component 5 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM169A | family with sequence similarity 169, member A |
| FAM222B | family with sequence similarity 222, member B |
| FBXO31 | F-box protein 31 |
| GALK1 | galactokinase 1 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GMPR | guanosine monophosphate reductase |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPX2 | glutathione peroxidase 2 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GTF2I | general transcription factor IIi |
| HIRA | histone cell cycle regulator |
| HIST1H4C | histone cluster 1, H4c |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFT81 | intraflagellar transport 81 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| KIZ | kizuna centrosomal protein |
| KLHL25 | kelch-like family member 25 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LOC730101 | uncharacterized LOC730101 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LYRM2 | LYR motif containing 2 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MBTD1 | mbt domain containing 1 |
| MEFV | Mediterranean fever |
| MIS18BP1 | MIS18 binding protein 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NIPAL2 | NIPA-like domain containing 2 |
| NLK | nemo-like kinase |
| NNT | nicotinamide nucleotide transhydrogenase |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NRSN2 | neurensin 2 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| OXTR | oxytocin receptor |
| PCDHB8 | protocadherin beta 8 |
| PCYOX1 | prenylcysteine oxidase 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRSS16 | protease, serine, 16 (thymus) |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| ROM1 | retinal outer segment membrane protein 1 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SIX1 | SIX homeobox 1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMIM14 | small integral membrane protein 14 |
| SNX16 | sorting nexin 16 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SYTL2 | synaptotagmin-like 2 |
| TBC1D17 | TBC1 domain family, member 17 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TTBK2 | tau tubulin kinase 2 |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USP18 | ubiquitin specific peptidase 18 |
| USP36 | ubiquitin specific peptidase 36 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZNF324 | zinc finger protein 324 |
