| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the tolbutamide-142 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ADIRF | adipogenesis regulatory factor |
| AFF2 | AF4/FMR2 family, member 2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ATXN2L | ataxin 2-like |
| BCL7A | B-cell CLL/lymphoma 7A |
| C10ORF76 | chromosome 10 open reading frame 76 |
| C2CD3 | C2 calcium-dependent domain containing 3 |
| CA11 | carbonic anhydrase XI |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CALHM2 | calcium homeostasis modulator 2 |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
| CASP8AP2 | caspase 8 associated protein 2 |
| CBR1 | carbonyl reductase 1 |
| CBX8 | chromobox homolog 8 |
| CCDC53 | coiled-coil domain containing 53 |
| CD44 | CD44 molecule (Indian blood group) |
| CHMP4A | charged multivesicular body protein 4A |
| CIC | capicua transcriptional repressor |
| CPT2 | carnitine palmitoyltransferase 2 |
| CXXC1 | CXXC finger protein 1 |
| DGUOK | deoxyguanosine kinase |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DVL3 | dishevelled segment polarity protein 3 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| FANCA | Fanconi anemia, complementation group A |
| FCHO1 | FCH domain only 1 |
| FKBP2 | FK506 binding protein 2, 13kDa |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| HDAC7 | histone deacetylase 7 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H3G | histone cluster 1, H3g |
| ICAM1 | intercellular adhesion molecule 1 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| IFT20 | intraflagellar transport 20 |
| IGF1R | insulin-like growth factor 1 receptor |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| LDAH | lipid droplet associated hydrolase |
| LHX3 | LIM homeobox 3 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| MBD1 | methyl-CpG binding domain protein 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MRPL34 | mitochondrial ribosomal protein L34 |
| NARFL | nuclear prelamin A recognition factor-like |
| NFATC2IP | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein |
| NMT1 | N-myristoyltransferase 1 |
| NOTCH3 | notch 3 |
| NUP210 | nucleoporin 210kDa |
| PC | pyruvate carboxylase |
| PCGF1 | polycomb group ring finger 1 |
| PCTP | phosphatidylcholine transfer protein |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PLEC | plectin |
| PLSCR3 | phospholipid scramblase 3 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| POT1 | protection of telomeres 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A |
| PPP1R8 | protein phosphatase 1, regulatory subunit 8 |
| PQLC1 | PQ loop repeat containing 1 |
| PRDX2 | peroxiredoxin 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRKCI | protein kinase C, iota |
| PTOV1 | prostate tumor overexpressed 1 |
| RAI14 | retinoic acid induced 14 |
| RNF13 | ring finger protein 13 |
| SAP18 | Sin3A-associated protein, 18kDa |
| SARAF | store-operated calcium entry-associated regulatory factor |
| SCPEP1 | serine carboxypeptidase 1 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIVA1 | SIVA1, apoptosis-inducing factor |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SURF2 | surfeit 2 |
| SYNGR3 | synaptogyrin 3 |
| TAOK1 | TAO kinase 1 |
| TEAD4 | TEA domain family member 4 |
| TESK1 | testis-specific kinase 1 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TP53BP1 | tumor protein p53 binding protein 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| TUBA3C | tubulin, alpha 3c |
| UBE3A | ubiquitin protein ligase E3A |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VRK3 | vaccinia related kinase 3 |
| ZBED1 | zinc finger, BED-type containing 1 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AGRP | agouti related neuropeptide |
| AMT | aminomethyltransferase |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BARX2 | BARX homeobox 2 |
| BCORL1 | BCL6 corepressor-like 1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA14 | carbonic anhydrase XIV |
| CA7 | carbonic anhydrase VII |
| CAV3 | caveolin 3 |
| CCDC7 | coiled-coil domain containing 7 |
| CD5 | CD5 molecule |
| CDC42SE1 | CDC42 small effector 1 |
| CFAP74 | cilia and flagella associated protein 74 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLCA1 | chloride channel accessory 1 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CNTFR | ciliary neurotrophic factor receptor |
| CNTNAP1 | contactin associated protein 1 |
| CPNE7 | copine VII |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTSK | cathepsin K |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DHCR24 | 24-dehydrocholesterol reductase |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DMBT1 | deleted in malignant brain tumors 1 |
| EDAR | ectodysplasin A receptor |
| EGR3 | early growth response 3 |
| EHD4 | EH-domain containing 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAAH | fatty acid amide hydrolase |
| FAM153A | family with sequence similarity 153, member A |
| FAM222B | family with sequence similarity 222, member B |
| FLNC | filamin C, gamma |
| FMO4 | flavin containing monooxygenase 4 |
| FMO6P | flavin containing monooxygenase 6 pseudogene |
| FMOD | fibromodulin |
| GGTLC1 | gamma-glutamyltransferase light chain 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR27 | G protein-coupled receptor 27 |
| GRPR | gastrin-releasing peptide receptor |
| GSTM5 | glutathione S-transferase mu 5 |
| HIST1H3E | histone cluster 1, H3e |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LRRC15 | leucine rich repeat containing 15 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAL | mal, T-cell differentiation protein |
| MAN2B2 | mannosidase, alpha, class 2B, member 2 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MOB3B | MOB kinase activator 3B |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| PALM | paralemmin |
| PIGR | polymeric immunoglobulin receptor |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PODXL | podocalyxin-like |
| PSAT1 | phosphoserine aminotransferase 1 |
| PZP | pregnancy-zone protein |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SLC13A4 | solute carrier family 13 (sodium/sulfate symporter), member 4 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SRPK3 | SRSF protein kinase 3 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| T | T, brachyury homolog (mouse) |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TEX40 | testis expressed 40 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TFCP2L1 | transcription factor CP2-like 1 |
| TIMM10 | translocase of inner mitochondrial membrane 10 homolog (yeast) |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 |
| TSC22D4 | TSC22 domain family, member 4 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR43 | WD repeat domain 43 |
| ZNF747 | zinc finger protein 747 |
