| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tolbutamide-2320 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AIF1 | allograft inflammatory factor 1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMACR | alpha-methylacyl-CoA racemase |
| ATG10 | autophagy related 10 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BCO1 | beta-carotene oxygenase 1 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CD1C | CD1c molecule |
| CDO1 | cysteine dioxygenase type 1 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CHRNB3 | cholinergic receptor, nicotinic, beta 3 (neuronal) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| COL5A2 | collagen, type V, alpha 2 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
| ERP44 | endoplasmic reticulum protein 44 |
| ESR2 | estrogen receptor 2 (ER beta) |
| FANCA | Fanconi anemia, complementation group A |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGFR1 | fibroblast growth factor receptor 1 |
| GYG2 | glycogenin 2 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFI35 | interferon-induced protein 35 |
| IL2RB | interleukin 2 receptor, beta |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRF4 | interferon regulatory factor 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KHSRP | KH-type splicing regulatory protein |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT83 | keratin 83, type II |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LMF2 | lipase maturation factor 2 |
| LOXL3 | lysyl oxidase-like 3 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MDFI | MyoD family inhibitor |
| MED16 | mediator complex subunit 16 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MMP11 | matrix metallopeptidase 11 |
| MST1L | macrophage stimulating 1-like |
| MTMR3 | myotubularin related protein 3 |
| MYOZ1 | myozenin 1 |
| NCR1 | natural cytotoxicity triggering receptor 1 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NEUROD4 | neuronal differentiation 4 |
| NUP54 | nucleoporin 54kDa |
| ONECUT2 | one cut homeobox 2 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| OSBP2 | oxysterol binding protein 2 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PAX5 | paired box 5 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PENK | proenkephalin |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PLAT | plasminogen activator, tissue |
| PRSS3 | protease, serine, 3 |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RASL11B | RAS-like, family 11, member B |
| RPS3A | ribosomal protein S3A |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| S100A13 | S100 calcium binding protein A13 |
| SDC3 | syndecan 3 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| SMG7-AS1 | SMG7 antisense RNA 1 |
| SPARCL1 | SPARC-like 1 (hevin) |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBC1D2 | TBC1 domain family, member 2 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TLN1 | talin 1 |
| TMEM246 | transmembrane protein 246 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| WDR62 | WD repeat domain 62 |
| WSB1 | WD repeat and SOCS box containing 1 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF518A | zinc finger protein 518A |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFAP1 | actin filament associated protein 1 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| AUTS2 | autism susceptibility candidate 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCORL1 | BCL6 corepressor-like 1 |
| BMP10 | bone morphogenetic protein 10 |
| BMP4 | bone morphogenetic protein 4 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CD83 | CD83 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CDK3 | cyclin-dependent kinase 3 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CUL9 | cullin 9 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| DUSP2 | dual specificity phosphatase 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EDAR | ectodysplasin A receptor |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| FAM50B | family with sequence similarity 50, member B |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FLCN | folliculin |
| FRK | fyn-related Src family tyrosine kinase |
| GFI1 | growth factor independent 1 transcription repressor |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4D | histone cluster 1, H4d |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL22 | interleukin 22 |
| JMJD4 | jumonji domain containing 4 |
| JUNB | jun B proto-oncogene |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIAA1107 | KIAA1107 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAP9 | microtubule-associated protein 9 |
| MB | myoglobin |
| MNX1 | motor neuron and pancreas homeobox 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OVOL1 | ovo-like zinc finger 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PER3 | period circadian clock 3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PMEL | premelanosome protein |
| PORCN | porcupine homolog (Drosophila) |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRR4 | proline rich 4 (lacrimal) |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB36 | RAB36, member RAS oncogene family |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RIN1 | Ras and Rab interactor 1 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPAG4 | sperm associated antigen 4 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TAPBP | TAP binding protein (tapasin) |
| TBKBP1 | TBK1 binding protein 1 |
| TCTN1 | tectonic family member 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMC7 | transmembrane channel-like 7 |
| TMEM180 | transmembrane protein 180 |
| TNS2 | tensin 2 |
| TRAIP | TRAF interacting protein |
| TUBG2 | tubulin, gamma 2 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| XK | X-linked Kx blood group |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) |
| ZNF134 | zinc finger protein 134 |
| ZNF506 | zinc finger protein 506 |
| ZNF862 | zinc finger protein 862 |
