| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tolbutamide-2359 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ARL3 | ADP-ribosylation factor-like 3 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CD52 | CD52 molecule |
| CDHR1 | cadherin-related family member 1 |
| CDK16 | cyclin-dependent kinase 16 |
| CLDN17 | claudin 17 |
| COMT | catechol-O-methyltransferase |
| CST1 | cystatin SN |
| DCN | decorin |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DUSP8 | dual specificity phosphatase 8 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EFCAB11 | EF-hand calcium binding domain 11 |
| EFNB3 | ephrin-B3 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| FAM50B | family with sequence similarity 50, member B |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FN1 | fibronectin 1 |
| FOXG1 | forkhead box G1 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GRM4 | glutamate receptor, metabotropic 4 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 |
| HFE | hemochromatosis |
| HRH1 | histamine receptor H1 |
| IFT140 | intraflagellar transport 140 |
| IGHM | immunoglobulin heavy constant mu |
| IL12B | interleukin 12B |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INO80D | INO80 complex subunit D |
| KCNH6 | potassium channel, voltage gated eag related subfamily H, member 6 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KIAA0895 | KIAA0895 |
| KIF1B | kinesin family member 1B |
| KRT81 | keratin 81, type II |
| KSR1 | kinase suppressor of ras 1 |
| LHFP | lipoma HMGIC fusion partner |
| LIMD2 | LIM domain containing 2 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC1720 | dihydrofolate reductase pseudogene |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAPT | microtubule-associated protein tau |
| MED25 | mediator complex subunit 25 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MTMR3 | myotubularin related protein 3 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NRF1 | nuclear respiratory factor 1 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PDLIM4 | PDZ and LIM domain 4 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PKP3 | plakophilin 3 |
| PLIN2 | perilipin 2 |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PVR | poliovirus receptor |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RBP3 | retinol binding protein 3, interstitial |
| RGS3 | regulator of G-protein signaling 3 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SNX13 | sorting nexin 13 |
| SPAG8 | sperm associated antigen 8 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STMN4 | stathmin-like 4 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TBCD | tubulin folding cofactor D |
| TBKBP1 | TBK1 binding protein 1 |
| TGFB1 | transforming growth factor, beta 1 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TLE3 | transducin-like enhancer of split 3 |
| TPM1 | tropomyosin 1 (alpha) |
| TRA | T cell receptor alpha locus |
| TSC22D4 | TSC22 domain family, member 4 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| TULP3 | tubby like protein 3 |
| UBXN1 | UBX domain protein 1 |
| UST | uronyl-2-sulfotransferase |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| XDH | xanthine dehydrogenase |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| AACS | acetoacetyl-CoA synthetase |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AEN | apoptosis enhancing nuclease |
| ALDOC | aldolase C, fructose-bisphosphate |
| ARF5 | ADP-ribosylation factor 5 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BORA | bora, aurora kinase A activator |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CCDC15 | coiled-coil domain containing 15 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CFL1 | cofilin 1 (non-muscle) |
| DDA1 | DET1 and DDB1 associated 1 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| DNASE1L1 | deoxyribonuclease I-like 1 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| EXOC5 | exocyst complex component 5 |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR22 | G protein-coupled receptor 22 |
| GTF2I | general transcription factor IIi |
| HAUS3 | HAUS augmin-like complex, subunit 3 |
| HIRA | histone cell cycle regulator |
| HOOK2 | hook microtubule-tethering protein 2 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLHDC4 | kelch domain containing 4 |
| LMNB1 | lamin B1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MBD5 | methyl-CpG binding domain protein 5 |
| MED22 | mediator complex subunit 22 |
| MED23 | mediator complex subunit 23 |
| MIS18BP1 | MIS18 binding protein 1 |
| MKKS | McKusick-Kaufman syndrome |
| MNS1 | meiosis-specific nuclear structural 1 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OCEL1 | occludin/ELL domain containing 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| OXR1 | oxidation resistance 1 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 |
| PCYOX1 | prenylcysteine oxidase 1 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PMCH | pro-melanin-concentrating hormone |
| PTER | phosphotriesterase related |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB5C | RAB5C, member RAS oncogene family |
| RABEPK | Rab9 effector protein with kelch motifs |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBM4B | RNA binding motif protein 4B |
| REEP4 | receptor accessory protein 4 |
| RNF141 | ring finger protein 141 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPIN1 | spindlin 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STIM1 | stromal interaction molecule 1 |
| TASP1 | taspase, threonine aspartase, 1 |
| TCTN2 | tectonic family member 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM134 | transmembrane protein 134 |
| TMEM159 | transmembrane protein 159 |
| TNRC6B | trinucleotide repeat containing 6B |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TRIM5 | tripartite motif containing 5 |
| TSC22D1 | TSC22 domain family, member 1 |
| UEVLD | UEV and lactate/malate dehyrogenase domains |
| UGDH | UDP-glucose 6-dehydrogenase |
| USP19 | ubiquitin specific peptidase 19 |
| WDR76 | WD repeat domain 76 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF140 | zinc finger protein 140 |
| ZNF253 | zinc finger protein 253 |
| ZNF32 | zinc finger protein 32 |
| ZNF35 | zinc finger protein 35 |
| ZNF408 | zinc finger protein 408 |
| ZNF654 | zinc finger protein 654 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
