| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the tolbutamide-3804 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALPL | alkaline phosphatase, liver/bone/kidney |
| AMPH | amphiphysin |
| ANGPTL2 | angiopoietin-like 2 |
| AQP1 | aquaporin 1 (Colton blood group) |
| ATP10A | ATPase, class V, type 10A |
| ATXN2L | ataxin 2-like |
| AVIL | advillin |
| BLVRA | biliverdin reductase A |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CADM3 | cell adhesion molecule 3 |
| CHD5 | chromodomain helicase DNA binding protein 5 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CROCCP3 | ciliary rootlet coiled-coil, rootletin pseudogene 3 |
| DCTN1 | dynactin 1 |
| DST | dystonin |
| DTNB | dystrobrevin, beta |
| EBF2 | early B-cell factor 2 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ENG | endoglin |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FABP6 | fatty acid binding protein 6, ileal |
| FBXL8 | F-box and leucine-rich repeat protein 8 |
| FRMD4B | FERM domain containing 4B |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| HAMP | hepcidin antimicrobial peptide |
| HAS1 | hyaluronan synthase 1 |
| HDAC6 | histone deacetylase 6 |
| HESX1 | HESX homeobox 1 |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HOXD11 | homeobox D11 |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| INHA | inhibin, alpha |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JPH3 | junctophilin 3 |
| KANK2 | KN motif and ankyrin repeat domains 2 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LCK | LCK proto-oncogene, Src family tyrosine kinase |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOC79999 | uncharacterized LOC79999 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRC48 | leucine rich repeat containing 48 |
| LTB4R | leukotriene B4 receptor |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MLNR | motilin receptor |
| MUC4 | mucin 4, cell surface associated |
| NPPA | natriuretic peptide A |
| ORM1 | orosomucoid 1 |
| OTOR | otoraplin |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLA2G3 | phospholipase A2, group III |
| PLG | plasminogen |
| POLDIP3 | polymerase (DNA-directed), delta interacting protein 3 |
| POMC | proopiomelanocortin |
| POU1F1 | POU class 1 homeobox 1 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PRDM14 | PR domain containing 14 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RAP1GAP | RAP1 GTPase activating protein |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SFTPB | surfactant protein B |
| SH3BP2 | SH3-domain binding protein 2 |
| SHOX2 | short stature homeobox 2 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STOML1 | stomatin (EPB72)-like 1 |
| SULF1 | sulfatase 1 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TGM4 | transglutaminase 4 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TRPM1 | transient receptor potential cation channel, subfamily M, member 1 |
| TSHB | thyroid stimulating hormone, beta |
| TUBB7P | tubulin, beta 7, pseudogene |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARSB | arylsulfatase B |
| AURKC | aurora kinase C |
| BBC3 | BCL2 binding component 3 |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CBS | cystathionine-beta-synthase |
| CCDC85C | coiled-coil domain containing 85C |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD82 | CD82 molecule |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNM3 | dynamin 3 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EGFL7 | EGF-like-domain, multiple 7 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EREG | epiregulin |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FAM53B | family with sequence similarity 53, member B |
| FBXO31 | F-box protein 31 |
| FKBP5 | FK506 binding protein 5 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRAMD1C | GRAM domain containing 1C |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HDAC11 | histone deacetylase 11 |
| HIST1H2AK | histone cluster 1, H2ak |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXB2 | homeobox B2 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| ITK | IL2-inducible T-cell kinase |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KIAA0754 | KIAA0754 |
| KLC2 | kinesin light chain 2 |
| KLF13 | Kruppel-like factor 13 |
| KLHL36 | kelch-like family member 36 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LRRC15 | leucine rich repeat containing 15 |
| MAGEF1 | melanoma antigen family F1 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MITF | microphthalmia-associated transcription factor |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| NDNF | neuron-derived neurotrophic factor |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| ONECUT2 | one cut homeobox 2 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAQR5 | progestin and adipoQ receptor family member V |
| PDE12 | phosphodiesterase 12 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PLBD1 | phospholipase B domain containing 1 |
| PLD2 | phospholipase D2 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| POM121 | POM121 transmembrane nucleoporin |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RNF43 | ring finger protein 43 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCIN | scinderin |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLAMF7 | SLAM family member 7 |
| SLC16A6 | solute carrier family 16, member 6 |
| SYCP2 | synaptonemal complex protein 2 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM19 | transmembrane protein 19 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TUBA3D | tubulin, alpha 3d |
| WDR19 | WD repeat domain 19 |
| WDR4 | WD repeat domain 4 |
| WDR91 | WD repeat domain 91 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF329 | zinc finger protein 329 |
| ZNF408 | zinc finger protein 408 |
| ZNF415 | zinc finger protein 415 |
| ZNF702P | zinc finger protein 702, pseudogene |
