| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tolbutamide-3886 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACVR1B | activin A receptor, type IB |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ARL3 | ADP-ribosylation factor-like 3 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BIN1 | bridging integrator 1 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 |
| CD58 | CD58 molecule |
| CD70 | CD70 molecule |
| CDC25C | cell division cycle 25C |
| CELF2 | CUGBP, Elav-like family member 2 |
| CLSTN3 | calsyntenin 3 |
| CNTNAP1 | contactin associated protein 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CPQ | carboxypeptidase Q |
| CTSZ | cathepsin Z |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| EFNA5 | ephrin-A5 |
| ELMO1 | engulfment and cell motility 1 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPN2 | epsin 2 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 |
| FAM188A | family with sequence similarity 188, member A |
| FAM63B | family with sequence similarity 63, member B |
| FFAR2 | free fatty acid receptor 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GIPR | gastric inhibitory polypeptide receptor |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GYG2 | glycogenin 2 |
| HBB | hemoglobin, beta |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIST1H3F | histone cluster 1, H3f |
| HIST1H4A | histone cluster 1, H4a |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| KAT6A | K(lysine) acetyltransferase 6A |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KLHL28 | kelch-like family member 28 |
| KRT8 | keratin 8, type II |
| LRRC15 | leucine rich repeat containing 15 |
| MAPT | microtubule-associated protein tau |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED16 | mediator complex subunit 16 |
| MED25 | mediator complex subunit 25 |
| MEGF6 | multiple EGF-like-domains 6 |
| METTL16 | methyltransferase like 16 |
| MMP13 | matrix metallopeptidase 13 |
| MYOZ3 | myozenin 3 |
| NFIB | nuclear factor I/B |
| NIPAL3 | NIPA-like domain containing 3 |
| NYX | nyctalopin |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PAX8 | paired box 8 |
| PEG3 | paternally expressed 3 |
| PITX1 | paired-like homeodomain 1 |
| PKP2 | plakophilin 2 |
| PRSS3 | protease, serine, 3 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAB40C | RAB40C, member RAS oncogene family |
| RAB6A | RAB6A, member RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SDC2 | syndecan 2 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SFTPB | surfactant protein B |
| SIRT5 | sirtuin 5 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SNX13 | sorting nexin 13 |
| SPPL2B | signal peptide peptidase like 2B |
| SPRR1A | small proline-rich protein 1A |
| STAC | SH3 and cysteine rich domain |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TGM4 | transglutaminase 4 |
| TRIM38 | tripartite motif containing 38 |
| TRPV4 | transient receptor potential cation channel, subfamily V, member 4 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VCL | vinculin |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZNF750 | zinc finger protein 750 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ARMC4 | armadillo repeat containing 4 |
| ATG2A | autophagy related 2A |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCO1 | beta-carotene oxygenase 1 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C3 | complement component 3 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CBX8 | chromobox homolog 8 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORO7 | coronin 7 |
| COX8A | cytochrome c oxidase subunit VIIIA (ubiquitous) |
| CSTA | cystatin A (stefin A) |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGKZ | diacylglycerol kinase, zeta |
| DNM1 | dynamin 1 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM120C | family with sequence similarity 120C |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FLJ22184 | |
| FMOD | fibromodulin |
| FRMD1 | FERM domain containing 1 |
| GALE | UDP-galactose-4-epimerase |
| GFI1 | growth factor independent 1 transcription repressor |
| GLB1L | galactosidase, beta 1-like |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H4D | histone cluster 1, H4d |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL22 | interleukin 22 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| JMJD4 | jumonji domain containing 4 |
| KIAA0319L | KIAA0319-like |
| KIAA1107 | KIAA1107 |
| KIF13B | kinesin family member 13B |
| KLHL25 | kelch-like family member 25 |
| MAP2 | microtubule-associated protein 2 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MEFV | Mediterranean fever |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MYO1F | myosin IF |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPTX1 | neuronal pentraxin I |
| ONECUT2 | one cut homeobox 2 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| POM121 | POM121 transmembrane nucleoporin |
| POMT2 | protein-O-mannosyltransferase 2 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RGS19 | regulator of G-protein signaling 19 |
| RIPPLY3 | ripply transcriptional repressor 3 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCAI | suppressor of cancer cell invasion |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| ST5 | suppression of tumorigenicity 5 |
| STAB2 | stabilin 2 |
| TMC5 | transmembrane channel-like 5 |
| TMEM121 | transmembrane protein 121 |
| TMEM38B | transmembrane protein 38B |
| TRIM21 | tripartite motif containing 21 |
| TSC22D4 | TSC22 domain family, member 4 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBTD1 | ubiquitin domain containing 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| WDR33 | WD repeat domain 33 |
| XAB2 | XPA binding protein 2 |
| ZNF286A | zinc finger protein 286A |
| ZNF329 | zinc finger protein 329 |
| ZNF74 | zinc finger protein 74 |
| ZW10 | zw10 kinetochore protein |
| ZXDC | ZXD family zinc finger C |
