| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the tolbutamide-4362 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ADRB3 | adrenoceptor beta 3 |
| AJAP1 | adherens junctions associated protein 1 |
| APOC1 | apolipoprotein C-I |
| AUTS2 | autism susceptibility candidate 2 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BST2 | bone marrow stromal cell antigen 2 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CDK19 | cyclin-dependent kinase 19 |
| CFAP70 | cilia and flagella associated protein 70 |
| CFP | complement factor properdin |
| CLCA1 | chloride channel accessory 1 |
| CLDN17 | claudin 17 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| EDNRA | endothelin receptor type A |
| EIF5A | eukaryotic translation initiation factor 5A |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FRMD1 | FERM domain containing 1 |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HAS1 | hyaluronan synthase 1 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H4C | histone cluster 1, H4c |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LRRC75B | leucine rich repeat containing 75B |
| LYZL6 | lysozyme-like 6 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MORN1 | MORN repeat containing 1 |
| MR1 | major histocompatibility complex, class I-related |
| MTA2 | metastasis associated 1 family, member 2 |
| MUC3B | mucin 3B, cell surface associated |
| MXD4 | MAX dimerization protein 4 |
| MYBPC3 | myosin binding protein C, cardiac |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NMUR1 | neuromedin U receptor 1 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OGG1 | 8-oxoguanine DNA glycosylase |
| OR1E1 | olfactory receptor, family 1, subfamily E, member 1 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRSS50 | protease, serine, 50 |
| PTCRA | pre T-cell antigen receptor alpha |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RAP2B | RAP2B, member of RAS oncogene family |
| RASIP1 | Ras interacting protein 1 |
| RGCC | regulator of cell cycle |
| RORB | RAR-related orphan receptor B |
| RUNX1 | runt-related transcription factor 1 |
| SAPCD1 | suppressor APC domain containing 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SHOX2 | short stature homeobox 2 |
| SLC19A3 | solute carrier family 19 (thiamine transporter), member 3 |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SNX13 | sorting nexin 13 |
| SPATA1 | spermatogenesis associated 1 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| TAGLN3 | transgelin 3 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TPM3 | tropomyosin 3 |
| TRIM15 | tripartite motif containing 15 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| USP22 | ubiquitin specific peptidase 22 |
| UTS2 | urotensin 2 |
| VCAN | versican |
| XIST | X inactive specific transcript (non-protein coding) |
| XPNPEP2 | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZNF415 | zinc finger protein 415 |
| Symbol | Name |
|---|---|
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALPK1 | alpha-kinase 1 |
| AMT | aminomethyltransferase |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARMC4 | armadillo repeat containing 4 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLDN1 | claudin 1 |
| CLGN | calmegin |
| CRBN | cereblon |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DAPK3 | death-associated protein kinase 3 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DEXI | Dexi homolog (mouse) |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| DNASE1L2 | deoxyribonuclease I-like 2 |
| DYSF | dysferlin |
| EFNA3 | ephrin-A3 |
| FADS2 | fatty acid desaturase 2 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXI1 | forkhead box I1 |
| FUZ | fuzzy planar cell polarity protein |
| G6PD | glucose-6-phosphate dehydrogenase |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H2AK | histone cluster 1, H2ak |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL22 | interleukin 22 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| KIF13B | kinesin family member 13B |
| KRT83 | keratin 83, type II |
| LPXN | leupaxin |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGEF1 | melanoma antigen family F1 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAP6D1 | MAP6 domain containing 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTCP1 | mature T-cell proliferation 1 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PADI3 | peptidyl arginine deiminase, type III |
| PCDH17 | protocadherin 17 |
| PCDHB8 | protocadherin beta 8 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PEX26 | peroxisomal biogenesis factor 26 |
| PICK1 | protein interacting with PRKCA 1 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLD3 | phospholipase D family, member 3 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PMCH | pro-melanin-concentrating hormone |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PPT2 | palmitoyl-protein thioesterase 2 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB5C | RAB5C, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RFXAP | regulatory factor X-associated protein |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF146 | ring finger protein 146 |
| RNF208 | ring finger protein 208 |
| RPL10L | ribosomal protein L10-like |
| RRAGB | Ras-related GTP binding B |
| S100A7 | S100 calcium binding protein A7 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SKI | SKI proto-oncogene |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SPIN1 | spindlin 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| TMEM209 | transmembrane protein 209 |
| TMEM242 | transmembrane protein 242 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TRAF4 | TNF receptor-associated factor 4 |
| UBXN6 | UBX domain protein 6 |
| WWC2 | WW and C2 domain containing 2 |
| ZNF10 | zinc finger protein 10 |
| ZNF532 | zinc finger protein 532 |
| ZNF750 | zinc finger protein 750 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
