| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tolbutamide-4540 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACOT11 | acyl-CoA thioesterase 11 |
| ACRV1 | acrosomal vesicle protein 1 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| ADPRH | ADP-ribosylarginine hydrolase |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL2 | B-cell CLL/lymphoma 2 |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit |
| CCDC71 | coiled-coil domain containing 71 |
| CCNO | cyclin O |
| CDK10 | cyclin-dependent kinase 10 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CISH | cytokine inducible SH2-containing protein |
| COL10A1 | collagen, type X, alpha 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| CUL5 | cullin 5 |
| CYTH1 | cytohesin 1 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| ELAC2 | elaC ribonuclease Z 2 |
| EMC3 | ER membrane protein complex subunit 3 |
| EML3 | echinoderm microtubule associated protein like 3 |
| EPS8L1 | EPS8-like 1 |
| ETV6 | ets variant 6 |
| FAM110B | family with sequence similarity 110, member B |
| FBXO31 | F-box protein 31 |
| FGF5 | fibroblast growth factor 5 |
| FH | fumarate hydratase |
| FHIT | fragile histidine triad |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GYG2 | glycogenin 2 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| IFNA14 | interferon, alpha 14 |
| IL36RN | interleukin 36 receptor antagonist |
| ING4 | inhibitor of growth family, member 4 |
| INO80D | INO80 complex subunit D |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IQCK | IQ motif containing K |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| LAMC3 | laminin, gamma 3 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LEPROT | leptin receptor overlapping transcript |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LIPE | lipase, hormone-sensitive |
| LMNB1 | lamin B1 |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC157562 | uncharacterized LOC157562 |
| MMP10 | matrix metallopeptidase 10 |
| MRAS | muscle RAS oncogene homolog |
| MTUS1 | microtubule associated tumor suppressor 1 |
| NCBP1 | nuclear cap binding protein subunit 1, 80kDa |
| NIPAL2 | NIPA-like domain containing 2 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
| PLEK | pleckstrin |
| PLXND1 | plexin D1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRY | PTPN13-like, Y-linked |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RAD51 | RAD51 recombinase |
| RARB | retinoic acid receptor, beta |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RRH | retinal pigment epithelium-derived rhodopsin homolog |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SCARB1 | scavenger receptor class B, member 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SP1 | Sp1 transcription factor |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SPRR2B | small proline-rich protein 2B |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TACR1 | tachykinin receptor 1 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMPRSS2 | transmembrane protease, serine 2 |
| TRIM2 | tripartite motif containing 2 |
| TUBA3C | tubulin, alpha 3c |
| TXK | TXK tyrosine kinase |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZCCHC4 | zinc finger, CCHC domain containing 4 |
| ZNF219 | zinc finger protein 219 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMC6 | armadillo repeat containing 6 |
| ARRB2 | arrestin, beta 2 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| AXIN1 | axin 1 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BAHD1 | bromo adjacent homology domain containing 1 |
| C3 | complement component 3 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC85C | coiled-coil domain containing 85C |
| CD101 | CD101 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDH7 | cadherin 7, type 2 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| EFNB1 | ephrin-B1 |
| EN2 | engrailed homeobox 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM186A | family with sequence similarity 186, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FHOD1 | formin homology 2 domain containing 1 |
| FKRP | fukutin related protein |
| FMO4 | flavin containing monooxygenase 4 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GPATCH3 | G patch domain containing 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC5 | histone deacetylase 5 |
| HIST1H2BO | histone cluster 1, H2bo |
| HOXA1 | homeobox A1 |
| JUNB | jun B proto-oncogene |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLF3 | Kruppel-like factor 3 (basic) |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC390998 | ribosomal protein L10 pseudogene |
| LOC729164 | hCG1732469 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MX1 | MX dynamin-like GTPase 1 |
| MXRA8 | matrix-remodelling associated 8 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NCS1 | neuronal calcium sensor 1 |
| NOL12 | nucleolar protein 12 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| ODF2 | outer dense fiber of sperm tails 2 |
| OLFML3 | olfactomedin-like 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PDZK1 | PDZ domain containing 1 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PORCN | porcupine homolog (Drosophila) |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF122 | ring finger protein 122 |
| RUNDC3B | RUN domain containing 3B |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SETD1A | SET domain containing 1A |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SYNPO | synaptopodin |
| TCTN2 | tectonic family member 2 |
| TMEM209 | transmembrane protein 209 |
| TMEM53 | transmembrane protein 53 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TPCN1 | two pore segment channel 1 |
| TRAIP | TRAF interacting protein |
| WDR33 | WD repeat domain 33 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YEATS2 | YEATS domain containing 2 |
| ZFHX3 | zinc finger homeobox 3 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF510 | zinc finger protein 510 |
| ZNF669 | zinc finger protein 669 |
| ZNF816 | zinc finger protein 816 |
