Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the tolfenamic acid-1437 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACTC1 | actin, alpha, cardiac muscle 1 |
ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
ARHGAP1 | Rho GTPase activating protein 1 |
ATG4B | autophagy related 4B, cysteine peptidase |
ATN1 | atrophin 1 |
BCL6 | B-cell CLL/lymphoma 6 |
BMP15 | bone morphogenetic protein 15 |
BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 |
CA5BP1 | carbonic anhydrase VB pseudogene 1 |
CASP8 | caspase 8, apoptosis-related cysteine peptidase |
CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
CCDC64 | coiled-coil domain containing 64 |
CD151 | CD151 molecule (Raph blood group) |
CD3E | CD3e molecule, epsilon (CD3-TCR complex) |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
COL5A3 | collagen, type V, alpha 3 |
COPS2 | COP9 signalosome subunit 2 |
CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
EGR4 | early growth response 4 |
FOS | FBJ murine osteosarcoma viral oncogene homolog |
GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
GLRA2 | glycine receptor, alpha 2 |
GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
GPR107 | G protein-coupled receptor 107 |
GPR27 | G protein-coupled receptor 27 |
GPRC5D | G protein-coupled receptor, class C, group 5, member D |
GRB7 | growth factor receptor-bound protein 7 |
HFE | hemochromatosis |
HIST1H1D | histone cluster 1, H1d |
HLA-DOA | major histocompatibility complex, class II, DO alpha |
HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
HTRA1 | HtrA serine peptidase 1 |
IL27RA | interleukin 27 receptor, alpha |
IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
IQCK | IQ motif containing K |
KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
KIAA1045 | KIAA1045 |
KLF6 | Kruppel-like factor 6 |
LAD1 | ladinin 1 |
LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
LPPR3 | lipid phosphate phosphatase-related protein type 3 |
LYZL6 | lysozyme-like 6 |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
MAP2K6 | mitogen-activated protein kinase kinase 6 |
MED16 | mediator complex subunit 16 |
MED18 | mediator complex subunit 18 |
MEF2C | myocyte enhancer factor 2C |
MICALL2 | MICAL-like 2 |
MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
MPDU1 | mannose-P-dolichol utilization defect 1 |
MYL10 | myosin, light chain 10, regulatory |
MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
NADK | NAD kinase |
NOL12 | nucleolar protein 12 |
OCRL | oculocerebrorenal syndrome of Lowe |
OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
ORC3 | origin recognition complex, subunit 3 |
PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
PLK4 | polo-like kinase 4 |
PNPLA4 | patatin-like phospholipase domain containing 4 |
PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
PXDN | peroxidasin |
RAB30 | RAB30, member RAS oncogene family |
RAD51D | RAD51 paralog D |
RHOD | ras homolog family member D |
RHOH | ras homolog family member H |
RNF39 | ring finger protein 39 |
RPS14 | ribosomal protein S14 |
SFTPC | surfactant protein C |
SLC17A4 | solute carrier family 17, member 4 |
SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
SORT1 | sortilin 1 |
SP140L | SP140 nuclear body protein-like |
ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
STAC | SH3 and cysteine rich domain |
SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
TCAF1 | TRPM8 channel-associated factor 1 |
TCF20 | transcription factor 20 (AR1) |
TCF3 | transcription factor 3 |
TCL1A | T-cell leukemia/lymphoma 1A |
TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
TK2 | thymidine kinase 2, mitochondrial |
TM7SF2 | transmembrane 7 superfamily member 2 |
TMEM74B | transmembrane protein 74B |
TMEM97 | transmembrane protein 97 |
TMPRSS6 | transmembrane protease, serine 6 |
TRIB2 | tribbles pseudokinase 2 |
TSPYL2 | TSPY-like 2 |
VARS | valyl-tRNA synthetase |
XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
ZNF236 | zinc finger protein 236 |
ZNF337 | zinc finger protein 337 |
ZNF518A | zinc finger protein 518A |
Symbol | Name |
---|---|
ABHD3 | abhydrolase domain containing 3 |
AHR | aryl hydrocarbon receptor |
ANPEP | alanyl (membrane) aminopeptidase |
AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
AP1G1 | adaptor-related protein complex 1, gamma 1 subunit |
ASCC2 | activating signal cointegrator 1 complex subunit 2 |
ATAT1 | alpha tubulin acetyltransferase 1 |
ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
AZI2 | 5-azacytidine induced 2 |
BANP | BTG3 associated nuclear protein |
BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 |
BRIX1 | BRX1, biogenesis of ribosomes |
C5ORF28 | chromosome 5 open reading frame 28 |
CASZ1 | castor zinc finger 1 |
CCDC6 | coiled-coil domain containing 6 |
CDC37L1 | cell division cycle 37-like 1 |
CENPT | centromere protein T |
CFAP74 | cilia and flagella associated protein 74 |
CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
CHSY1 | chondroitin sulfate synthase 1 |
CLTCL1 | clathrin, heavy chain-like 1 |
CMTR1 | cap methyltransferase 1 |
CRYBG3 | beta-gamma crystallin domain containing 3 |
DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
DENND4A | DENN/MADD domain containing 4A |
DMXL1 | Dmx-like 1 |
EP300 | E1A binding protein p300 |
EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
ERO1L | ERO1-like (S. cerevisiae) |
FANCF | Fanconi anemia, complementation group F |
FKBP2 | FK506 binding protein 2, 13kDa |
GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
GOLM1 | golgi membrane protein 1 |
GRPR | gastrin-releasing peptide receptor |
GRWD1 | glutamate-rich WD repeat containing 1 |
GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
GUSBP3 | glucuronidase, beta pseudogene 3 |
HOMER1 | homer scaffolding protein 1 |
KCTD3 | potassium channel tetramerization domain containing 3 |
KDELC1 | KDEL (Lys-Asp-Glu-Leu) containing 1 |
KLHL21 | kelch-like family member 21 |
KPTN | kaptin (actin binding protein) |
LOC642236 | FSHD region gene 1 pseudogene |
MAGOHB | mago-nashi homolog B (Drosophila) |
MAGT1 | magnesium transporter 1 |
MAPK10 | mitogen-activated protein kinase 10 |
MCTP1 | multiple C2 domains, transmembrane 1 |
MEX3C | mex-3 RNA binding family member C |
MORC3 | MORC family CW-type zinc finger 3 |
NIP7 | NIP7, nucleolar pre-rRNA processing protein |
NUCB2 | nucleobindin 2 |
NXPH3 | neurexophilin 3 |
ORC6 | origin recognition complex, subunit 6 |
PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
PCNXL4 | pecanex-like 4 (Drosophila) |
PCSK7 | proprotein convertase subtilisin/kexin type 7 |
PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
PLA2G12A | phospholipase A2, group XIIA |
PNRC1 | proline-rich nuclear receptor coactivator 1 |
PRKX | protein kinase, X-linked |
PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 |
QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
RBMS3 | RNA binding motif, single stranded interacting protein 3 |
RECQL4 | RecQ protein-like 4 |
RP2 | retinitis pigmentosa 2 (X-linked recessive) |
RPL26 | ribosomal protein L26 |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
RUFY2 | RUN and FYVE domain containing 2 |
RWDD3 | RWD domain containing 3 |
SETD1B | SET domain containing 1B |
SETD8 | SET domain containing (lysine methyltransferase) 8 |
SETMAR | SET domain and mariner transposase fusion gene |
SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
SLMO2 | slowmo homolog 2 (Drosophila) |
SNX10 | sorting nexin 10 |
SNX15 | sorting nexin 15 |
SPC25 | SPC25, NDC80 kinetochore complex component |
SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
STK25 | serine/threonine kinase 25 |
TMEM104 | transmembrane protein 104 |
TMEM80 | transmembrane protein 80 |
TRAC | T cell receptor alpha constant |
TRAPPC11 | trafficking protein particle complex 11 |
TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
TSSC4 | tumor suppressing subtransferable candidate 4 |
TTF2 | transcription termination factor, RNA polymerase II |
UNC93B1 | unc-93 homolog B1 (C. elegans) |
WDR11 | WD repeat domain 11 |
WT1-AS | WT1 antisense RNA |
XYLT1 | xylosyltransferase I |
ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
ZCCHC10 | zinc finger, CCHC domain containing 10 |
ZNF160 | zinc finger protein 160 |