| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tolfenamic acid-6354 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATP10B | ATPase, class V, type 10B |
| BDKRB1 | bradykinin receptor B1 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC40 | coiled-coil domain containing 40 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD82 | CD82 molecule |
| CD8B | CD8b molecule |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEP250 | centrosomal protein 250kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CIB2 | calcium and integrin binding family member 2 |
| CISH | cytokine inducible SH2-containing protein |
| CLIC5 | chloride intracellular channel 5 |
| CLTB | clathrin, light chain B |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| ELMO2 | engulfment and cell motility 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FADS3 | fatty acid desaturase 3 |
| FAM13A | family with sequence similarity 13, member A |
| FMOD | fibromodulin |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GOLGA2 | golgin A2 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GPX2 | glutathione peroxidase 2 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXB2 | homeobox B2 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFFO1 | intermediate filament family orphan 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INO80B | INO80 complex subunit B |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KHK | ketohexokinase (fructokinase) |
| KRT15 | keratin 15, type I |
| KRT24 | keratin 24, type I |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MED25 | mediator complex subunit 25 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MMP25 | matrix metallopeptidase 25 |
| MORN1 | MORN repeat containing 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| N4BP1 | NEDD4 binding protein 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NF2 | neurofibromin 2 (merlin) |
| NLGN1 | neuroligin 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRF1 | nuclear respiratory factor 1 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| PALM | paralemmin |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PLD2 | phospholipase D2 |
| PQBP1 | polyglutamine binding protein 1 |
| PTCD1 | pentatricopeptide repeat domain 1 |
| RAB36 | RAB36, member RAS oncogene family |
| REST | RE1-silencing transcription factor |
| RIN3 | Ras and Rab interactor 3 |
| RPL10L | ribosomal protein L10-like |
| RPS28 | ribosomal protein S28 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SERTAD3 | SERTA domain containing 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAB2 | stabilin 2 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| TBX1 | T-box 1 |
| TBX2 | T-box 2 |
| UBOX5 | U-box domain containing 5 |
| UBQLN4 | ubiquilin 4 |
| USB1 | U6 snRNA biogenesis 1 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase |
| ZNF428 | zinc finger protein 428 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ABHD8 | abhydrolase domain containing 8 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFAP1 | actin filament associated protein 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BEX1 | brain expressed, X-linked 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLEC2B | C-type lectin domain family 2, member B |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CORO2A | coronin, actin binding protein, 2A |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EGF | epidermal growth factor |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPHA4 | EPH receptor A4 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EXOC5 | exocyst complex component 5 |
| FADS2 | fatty acid desaturase 2 |
| FAM169A | family with sequence similarity 169, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GTF2I | general transcription factor IIi |
| HDAC5 | histone deacetylase 5 |
| HHLA3 | HERV-H LTR-associating 3 |
| HOXA4 | homeobox A4 |
| HOXC5 | homeobox C5 |
| IL4R | interleukin 4 receptor |
| IREB2 | iron-responsive element binding protein 2 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LMBR1L | limb development membrane protein 1-like |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MPI | mannose phosphate isomerase |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MYL5 | myosin, light chain 5, regulatory |
| NDRG4 | NDRG family member 4 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OLFML2A | olfactomedin-like 2A |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDZD2 | PDZ domain containing 2 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLH | polymerase (DNA directed), eta |
| POMT2 | protein-O-mannosyltransferase 2 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRPH | peripherin |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SESN1 | sestrin 1 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SREK1IP1 | SREK1-interacting protein 1 |
| STAC | SH3 and cysteine rich domain |
| SYTL2 | synaptotagmin-like 2 |
| TCTN1 | tectonic family member 1 |
| TMEM209 | transmembrane protein 209 |
| TNS2 | tensin 2 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TSPAN1 | tetraspanin 1 |
| TTC26 | tetratricopeptide repeat domain 26 |
| WDR18 | WD repeat domain 18 |
| WDR37 | WD repeat domain 37 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF571 | zinc finger protein 571 |
