| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the tolmetin-3347 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ABCC8 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
| ACVR1B | activin A receptor, type IB |
| AHCYL1 | adenosylhomocysteinase-like 1 |
| AHNAK | AHNAK nucleoprotein |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| AQP1 | aquaporin 1 (Colton blood group) |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BMP15 | bone morphogenetic protein 15 |
| CACNG2 | calcium channel, voltage-dependent, gamma subunit 2 |
| CALD1 | caldesmon 1 |
| CAV2 | caveolin 2 |
| CCKAR | cholecystokinin A receptor |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNJL | cyclin J-like |
| CD70 | CD70 molecule |
| CDK12 | cyclin-dependent kinase 12 |
| CDK6 | cyclin-dependent kinase 6 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CEP41 | centrosomal protein 41kDa |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CNTNAP2 | contactin associated protein-like 2 |
| CSF1R | colony stimulating factor 1 receptor |
| CYLD | cylindromatosis (turban tumor syndrome) |
| EHD1 | EH-domain containing 1 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ERCC2 | excision repair cross-complementation group 2 |
| FHL1 | four and a half LIM domains 1 |
| FLJ11292 | |
| FOXO4 | forkhead box O4 |
| FRMD1 | FERM domain containing 1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GCKR | glucokinase (hexokinase 4) regulator |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GOLGA8A | golgin A8 family, member A |
| GPC1 | glypican 1 |
| HMOX1 | heme oxygenase 1 |
| IFNW1 | interferon, omega 1 |
| IL1B | interleukin 1, beta |
| INHBA | inhibin, beta A |
| IQCA1 | IQ motif containing with AAA domain 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| LAMB2 | laminin, beta 2 (laminin S) |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| NCOR2 | nuclear receptor corepressor 2 |
| NEUROG2 | neurogenin 2 |
| NF1 | neurofibromin 1 |
| NME5 | NME/NM23 family member 5 |
| NRG2 | neuregulin 2 |
| NUP188 | nucleoporin 188kDa |
| ONECUT2 | one cut homeobox 2 |
| PAX5 | paired box 5 |
| PCDH1 | protocadherin 1 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLK4 | polo-like kinase 4 |
| PLXNA2 | plexin A2 |
| PODNL1 | podocan-like 1 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| RAB3B | RAB3B, member RAS oncogene family |
| RAB6A | RAB6A, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| RND1 | Rho family GTPase 1 |
| RNF39 | ring finger protein 39 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RUNX1 | runt-related transcription factor 1 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAFB2 | scaffold attachment factor B2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPRR1B | small proline-rich protein 1B |
| STAB2 | stabilin 2 |
| STC1 | stanniocalcin 1 |
| STOML1 | stomatin (EPB72)-like 1 |
| STRN | striatin, calmodulin binding protein |
| TEX40 | testis expressed 40 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TPP1 | tripeptidyl peptidase I |
| TYRO3 | TYRO3 protein tyrosine kinase |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WDR55 | WD repeat domain 55 |
| WSB1 | WD repeat and SOCS box containing 1 |
| WTAP | Wilms tumor 1 associated protein |
| YY2 | YY2 transcription factor |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| AFAP1 | actin filament associated protein 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BMP4 | bone morphogenetic protein 4 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC69 | coiled-coil domain containing 69 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ETNK2 | ethanolamine kinase 2 |
| FAM188A | family with sequence similarity 188, member A |
| FAM53B | family with sequence similarity 53, member B |
| FBXO22 | F-box protein 22 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FER | fer (fps/fes related) tyrosine kinase |
| FOXN2 | forkhead box N2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GFI1 | growth factor independent 1 transcription repressor |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR27 | G protein-coupled receptor 27 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC5 | histone deacetylase 5 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BO | histone cluster 1, H2bo |
| HOXA4 | homeobox A4 |
| IQCG | IQ motif containing G |
| KAT2A | K(lysine) acetyltransferase 2A |
| KIAA1107 | KIAA1107 |
| KIF13B | kinesin family member 13B |
| KLHL21 | kelch-like family member 21 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMBR1L | limb development membrane protein 1-like |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL2B | methyltransferase like 2B |
| MITF | microphthalmia-associated transcription factor |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MTCP1 | mature T-cell proliferation 1 |
| MYOZ3 | myozenin 3 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARVA | parvin, alpha |
| PCDHB3 | protocadherin beta 3 |
| PCDHB8 | protocadherin beta 8 |
| PDE8B | phosphodiesterase 8B |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLD2 | phospholipase D2 |
| POPDC3 | popeye domain containing 3 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| RAB3D | RAB3D, member RAS oncogene family |
| RCAN3 | RCAN family member 3 |
| RLN1 | relaxin 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIRAL2 | SIR2 antiphage like 2 |
| SKI | SKI proto-oncogene |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPATA2L | spermatogenesis associated 2-like |
| TCTA | T-cell leukemia translocation altered |
| TESC | tescalcin |
| TFF2 | trefoil factor 2 |
| THRB | thyroid hormone receptor, beta |
| TLR5 | toll-like receptor 5 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TPTE | transmembrane phosphatase with tensin homology |
| TRIM36 | tripartite motif containing 36 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| VASH2 | vasohibin 2 |
| VLDLR | very low density lipoprotein receptor |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS9D1 | VPS9 domain containing 1 |
| WDR19 | WD repeat domain 19 |
| WDR25 | WD repeat domain 25 |
| ZFHX2 | zinc finger homeobox 2 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF16 | zinc finger protein 16 |
| ZNF324 | zinc finger protein 324 |
| ZNF358 | zinc finger protein 358 |
| ZNF428 | zinc finger protein 428 |
| ZNF446 | zinc finger protein 446 |
| ZNF778 | zinc finger protein 778 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
