| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
196 genes differentially expressed following the tolmetin-4167 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABI2 | abl-interactor 2 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ATP10B | ATPase, class V, type 10B |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| BUD31 | BUD31 homolog (S. cerevisiae) |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CALB1 | calbindin 1, 28kDa |
| CALCR | calcitonin receptor |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC181 | coiled-coil domain containing 181 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHI3L2 | chitinase 3-like 2 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 |
| COL13A1 | collagen, type XIII, alpha 1 |
| CST4 | cystatin S |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DMPK | dystrophia myotonica-protein kinase |
| EDN1 | endothelin 1 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ESR1 | estrogen receptor 1 |
| FAM153A | family with sequence similarity 153, member A |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FCMR | Fc fragment of IgM receptor |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GPR85 | G protein-coupled receptor 85 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HDAC7 | histone deacetylase 7 |
| HES2 | hes family bHLH transcription factor 2 |
| HIST1H2BM | histone cluster 1, H2bm |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL23A | interleukin 23, alpha subunit p19 |
| IL33R | interleukin 33 receptor |
| ITGA7 | integrin, alpha 7 |
| ITM2C | integral membrane protein 2C |
| KALRN | kalirin, RhoGEF kinase |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| LCMT2 | leucine carboxyl methyltransferase 2 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MED18 | mediator complex subunit 18 |
| MED25 | mediator complex subunit 25 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MPZ | myelin protein zero |
| NPR2 | natriuretic peptide receptor 2 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| PCDH1 | protocadherin 1 |
| PCDHA9 | protocadherin alpha 9 |
| PDE10A | phosphodiesterase 10A |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PLSCR2 | phospholipid scramblase 2 |
| PML | promyelocytic leukemia |
| POFUT1 | protein O-fucosyltransferase 1 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRDX2 | peroxiredoxin 2 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RBBP4 | retinoblastoma binding protein 4 |
| REEP2 | receptor accessory protein 2 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| S100A8 | S100 calcium binding protein A8 |
| SATB2 | SATB homeobox 2 |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC5A12 | solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SYMPK | symplekin |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TBX6 | T-box 6 |
| TRBC1 | T cell receptor beta constant 1 |
| USP29 | ubiquitin specific peptidase 29 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF44 | zinc finger protein 44 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATG10 | autophagy related 10 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC71 | coiled-coil domain containing 71 |
| CFAP70 | cilia and flagella associated protein 70 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CPB2 | carboxypeptidase B2 (plasma) |
| CRY2 | cryptochrome circadian clock 2 |
| CUL9 | cullin 9 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EFNA3 | ephrin-A3 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC2 | excision repair cross-complementation group 2 |
| FAM169A | family with sequence similarity 169, member A |
| FLJ22184 | |
| FOXI1 | forkhead box I1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GFI1 | growth factor independent 1 transcription repressor |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GSPT2 | G1 to S phase transition 2 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXC4 | homeobox C4 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IL18 | interleukin 18 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIAA0319L | KIAA0319-like |
| KLHL29 | kelch-like family member 29 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT83 | keratin 83, type II |
| LATS1 | large tumor suppressor kinase 1 |
| LEFTY2 | left-right determination factor 2 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAGEA3 | melanoma antigen family A3 |
| MDM4 | MDM4, p53 regulator |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTCP1 | mature T-cell proliferation 1 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NEUROD1 | neuronal differentiation 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| OCA2 | oculocutaneous albinism II |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCDHB3 | protocadherin beta 3 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POM121 | POM121 transmembrane nucleoporin |
| PQLC2 | PQ loop repeat containing 2 |
| PRAMEF11 | PRAME family member 11 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| RPH3A | rabphilin 3A |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SGCE | sarcoglycan, epsilon |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SNTA1 | syntrophin, alpha 1 |
| SP1 | Sp1 transcription factor |
| SYCE1L | synaptonemal complex central element protein 1-like |
| TAS2R4 | taste receptor, type 2, member 4 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TLR2 | toll-like receptor 2 |
| TMEM242 | transmembrane protein 242 |
| TRIM25 | tripartite motif containing 25 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VIM | vimentin |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR62 | WD repeat domain 62 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF197 | zinc finger protein 197 |
| ZNF23 | zinc finger protein 23 |
| ZNF480 | zinc finger protein 480 |
