| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the tolnaftate-2001 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANKRD12 | ankyrin repeat domain 12 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOC4 | apolipoprotein C-IV |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ART1 | ADP-ribosyltransferase 1 |
| AZI2 | 5-azacytidine induced 2 |
| BCLAF1 | BCL2-associated transcription factor 1 |
| CCPG1 | cell cycle progression 1 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CIAO1 | cytosolic iron-sulfur assembly component 1 |
| CLCN3 | chloride channel, voltage-sensitive 3 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COX5B | cytochrome c oxidase subunit Vb |
| CPA4 | carboxypeptidase A4 |
| CRCP | CGRP receptor component |
| CTSS | cathepsin S |
| CUL4A | cullin 4A |
| CYB561 | cytochrome b561 |
| DUSP2 | dual specificity phosphatase 2 |
| EFNA5 | ephrin-A5 |
| EFNB3 | ephrin-B3 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| EIF4E | eukaryotic translation initiation factor 4E |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 |
| ERLIN2 | ER lipid raft associated 2 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAM3C | family with sequence similarity 3, member C |
| FKTN | fukutin |
| GDF11 | growth differentiation factor 11 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPALPP1 | GPALPP motifs containing 1 |
| GPR12 | G protein-coupled receptor 12 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 |
| IRF2 | interferon regulatory factor 2 |
| ITM2B | integral membrane protein 2B |
| KLHL20 | kelch-like family member 20 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) |
| KTN1 | kinectin 1 (kinesin receptor) |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LIN7C | lin-7 homolog C (C. elegans) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| LTN1 | listerin E3 ubiquitin protein ligase 1 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase |
| MICALL1 | MICAL-like 1 |
| MPHOSPH9 | M-phase phosphoprotein 9 |
| NAAA | N-acylethanolamine acid amidase |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NHLRC2 | NHL repeat containing 2 |
| NRBP1 | nuclear receptor binding protein 1 |
| PLCD1 | phospholipase C, delta 1 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
| RIF1 | replication timing regulatory factor 1 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RPL14 | ribosomal protein L14 |
| RPL37A | ribosomal protein L37a |
| RPL38 | ribosomal protein L38 |
| RPS11 | ribosomal protein S11 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SEC23B | Sec23 homolog B (S. cerevisiae) |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SRSF11 | serine/arginine-rich splicing factor 11 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit |
| SUGP1 | SURP and G patch domain containing 1 |
| SUMO1 | small ubiquitin-like modifier 1 |
| TANK | TRAF family member-associated NFKB activator |
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMPRSS6 | transmembrane protease, serine 6 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBXN2B | UBX domain protein 2B |
| USF2 | upstream transcription factor 2, c-fos interacting |
| USP12 | ubiquitin specific peptidase 12 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| WIZ | widely interspaced zinc finger motifs |
| YIPF4 | Yip1 domain family, member 4 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF160 | zinc finger protein 160 |
| Symbol | Name |
|---|---|
| AATF | apoptosis antagonizing transcription factor |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ADM | adrenomedullin |
| AGO3 | argonaute RISC catalytic component 3 |
| ANXA2P2 | annexin A2 pseudogene 2 |
| ANXA6 | annexin A6 |
| APH1A | APH1A gamma secretase subunit |
| APOBR | apolipoprotein B receptor |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATF3 | activating transcription factor 3 |
| ATG4A | autophagy related 4A, cysteine peptidase |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCAP31 | B-cell receptor-associated protein 31 |
| BIN2 | bridging integrator 2 |
| BST1 | bone marrow stromal cell antigen 1 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNA1 | cyclin A1 |
| CCNL2 | cyclin L2 |
| CDC45 | cell division cycle 45 |
| CDIP1 | cell death-inducing p53 target 1 |
| CDK5 | cyclin-dependent kinase 5 |
| CLDN15 | claudin 15 |
| CLDND1 | claudin domain containing 1 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| COG7 | component of oligomeric golgi complex 7 |
| CPNE1 | copine I |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CYBA | cytochrome b-245, alpha polypeptide |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| DOK3 | docking protein 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ERO1L | ERO1-like (S. cerevisiae) |
| GOLM1 | golgi membrane protein 1 |
| GPN2 | GPN-loop GTPase 2 |
| GSR | glutathione reductase |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| HS1BP3 | HCLS1 binding protein 3 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 |
| KDM1A | lysine (K)-specific demethylase 1A |
| KIZ | kizuna centrosomal protein |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LGALS1 | lectin, galactoside-binding, soluble, 1 |
| LIMD2 | LIM domain containing 2 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LMAN2L | lectin, mannose-binding 2-like |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LUC7L | LUC7-like (S. cerevisiae) |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| NAGK | N-acetylglucosamine kinase |
| NCF2 | neutrophil cytosolic factor 2 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PCTP | phosphatidylcholine transfer protein |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 |
| PEF1 | penta-EF-hand domain containing 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| RAB4B | RAB4B, member RAS oncogene family |
| RNF113A | ring finger protein 113A |
| RNF130 | ring finger protein 130 |
| RNF146 | ring finger protein 146 |
| S100A10 | S100 calcium binding protein A10 |
| SAP30L | SAP30-like |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SRRD | SRR1 domain containing |
| STAU2 | staufen double-stranded RNA binding protein 2 |
| STK25 | serine/threonine kinase 25 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 |
| TDRD7 | tudor domain containing 7 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| VILL | villin-like |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR46 | WD repeat domain 46 |
| ZNF263 | zinc finger protein 263 |
