| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tolnaftate-4221 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AFF2 | AF4/FMR2 family, member 2 |
| AGTR1 | angiotensin II receptor, type 1 |
| AGXT | alanine-glyoxylate aminotransferase |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALPI | alkaline phosphatase, intestinal |
| ALPP | alkaline phosphatase, placental |
| B3GALT2 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha |
| CATR1 | CATR tumorigenicity conversion 1 |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD163 | CD163 molecule |
| CD177 | CD177 molecule |
| CD52 | CD52 molecule |
| CDKL5 | cyclin-dependent kinase-like 5 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLEC4A | C-type lectin domain family 4, member A |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CRH | corticotropin releasing hormone |
| CST5 | cystatin D |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DAB1 | Dab, reelin signal transducer, homolog 1 (Drosophila) |
| DENND1C | DENN/MADD domain containing 1C |
| DICER1 | dicer 1, ribonuclease type III |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DLX2 | distal-less homeobox 2 |
| DOCK9 | dedicator of cytokinesis 9 |
| DRP2 | dystrophin related protein 2 |
| EDDM3B | epididymal protein 3B |
| ELK1 | ELK1, member of ETS oncogene family |
| EPHA1 | EPH receptor A1 |
| EPO | erythropoietin |
| FAM149A | family with sequence similarity 149, member A |
| FOXB1 | forkhead box B1 |
| FPR1 | formyl peptide receptor 1 |
| GDF10 | growth differentiation factor 10 |
| GLP1R | glucagon-like peptide 1 receptor |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| HES2 | hes family bHLH transcription factor 2 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| IAPP | islet amyloid polypeptide |
| IFNA2 | interferon, alpha 2 |
| IGL | immunoglobulin lambda locus |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KLK13 | kallikrein-related peptidase 13 |
| LARGE | like-glycosyltransferase |
| LILRA5 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LST1 | leukocyte specific transcript 1 |
| LY6G6D | lymphocyte antigen 6 complex, locus G6D |
| LZTS1 | leucine zipper, putative tumor suppressor 1 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MBNL1 | muscleblind-like splicing regulator 1 |
| MSLN | mesothelin |
| MYOZ1 | myozenin 1 |
| NCR1 | natural cytotoxicity triggering receptor 1 |
| NMUR1 | neuromedin U receptor 1 |
| NPC1L1 | NPC1-like 1 |
| OPRL1 | opiate receptor-like 1 |
| OR1A2 | olfactory receptor, family 1, subfamily A, member 2 |
| POU6F1 | POU class 6 homeobox 1 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PTTG2 | pituitary tumor-transforming 2 |
| PYY | peptide YY |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBM12B-AS1 | RBM12B antisense RNA 1 |
| RBP3 | retinol binding protein 3, interstitial |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RHO | rhodopsin |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SIRT4 | sirtuin 4 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SPI1 | Spi-1 proto-oncogene |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| STMN2 | stathmin 2 |
| SYNPO2L | synaptopodin 2-like |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TEK | TEK tyrosine kinase, endothelial |
| TMEM176B | transmembrane protein 176B |
| TRAPPC9 | trafficking protein particle complex 9 |
| TRPC7 | transient receptor potential cation channel, subfamily C, member 7 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSHR | thyroid stimulating hormone receptor |
| TUBB2B | tubulin, beta 2B class IIb |
| UBASH3A | ubiquitin associated and SH3 domain containing A |
| VAMP5 | vesicle-associated membrane protein 5 |
| VTN | vitronectin |
| ZNRF4 | zinc and ring finger 4 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADCY6 | adenylate cyclase 6 |
| AFAP1 | actin filament associated protein 1 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BAG4 | BCL2-associated athanogene 4 |
| BNC1 | basonuclin 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CDK3 | cyclin-dependent kinase 3 |
| CEP112 | centrosomal protein 112kDa |
| CEP131 | centrosomal protein 131kDa |
| CHM | choroideremia (Rab escort protein 1) |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CRYGC | crystallin, gamma C |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DMTN | dematin actin binding protein |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| EGF | epidermal growth factor |
| ERF | Ets2 repressor factor |
| FAM69A | family with sequence similarity 69, member A |
| FANCC | Fanconi anemia, complementation group C |
| FLCN | folliculin |
| FUZ | fuzzy planar cell polarity protein |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GMPR | guanosine monophosphate reductase |
| GPR176 | G protein-coupled receptor 176 |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H3F | histone cluster 1, H3f |
| ICOS | inducible T-cell co-stimulator |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| INCENP | inner centromere protein antigens 135/155kDa |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIAA0319L | KIAA0319-like |
| KLF3 | Kruppel-like factor 3 (basic) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LRRC6 | leucine rich repeat containing 6 |
| LTC4S | leukotriene C4 synthase |
| METTL16 | methyltransferase like 16 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTCP1 | mature T-cell proliferation 1 |
| NDP | Norrie disease (pseudoglioma) |
| NLGN1 | neuroligin 1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| ONECUT2 | one cut homeobox 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PAX9 | paired box 9 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE8B | phosphodiesterase 8B |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| POM121 | POM121 transmembrane nucleoporin |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAI2 | retinoic acid induced 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF123 | ring finger protein 123 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SIX1 | SIX homeobox 1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SLN | sarcolipin |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SPEG | SPEG complex locus |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TAGLN3 | transgelin 3 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM242 | transmembrane protein 242 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TXLNG | taxilin gamma |
| ULBP2 | UL16 binding protein 2 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VGLL3 | vestigial-like family member 3 |
| WDR76 | WD repeat domain 76 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF227 | zinc finger protein 227 |
| ZNF254 | zinc finger protein 254 |
| ZNF34 | zinc finger protein 34 |
| ZNF391 | zinc finger protein 391 |
