| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the tolnaftate-4805 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide |
| AIDA | axin interactor, dorsalization associated |
| AKAP10 | A kinase (PRKA) anchor protein 10 |
| AKTIP | AKT interacting protein |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ATG5 | autophagy related 5 |
| ATM | ATM serine/threonine kinase |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CA4 | carbonic anhydrase IV |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CALU | calumenin |
| CAPRIN1 | cell cycle associated protein 1 |
| CCNG2 | cyclin G2 |
| CD46 | CD46 molecule, complement regulatory protein |
| CDC25C | cell division cycle 25C |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLDND1 | claudin domain containing 1 |
| CLGN | calmegin |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CTBS | chitobiase, di-N-acetyl- |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 |
| EFNA3 | ephrin-A3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPOR | erythropoietin receptor |
| ETNK1 | ethanolamine kinase 1 |
| EXOC5 | exocyst complex component 5 |
| FAS | Fas cell surface death receptor |
| FDX1 | ferredoxin 1 |
| FFAR3 | free fatty acid receptor 3 |
| FH | fumarate hydratase |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GPNMB | glycoprotein (transmembrane) nmb |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HSPA4 | heat shock 70kDa protein 4 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KLF13 | Kruppel-like factor 13 |
| LINC00094 | long intergenic non-protein coding RNA 94 |
| LOC440434 | aminopeptidase puromycin sensitive pseudogene |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPK1 | mitogen-activated protein kinase 1 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 |
| MCL1 | myeloid cell leukemia 1 |
| MCM4 | minichromosome maintenance complex component 4 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MTM1 | myotubularin 1 |
| NCKAP1 | NCK-associated protein 1 |
| NEK3 | NIMA-related kinase 3 |
| NOTCH2 | notch 2 |
| NPR3 | natriuretic peptide receptor 3 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| PARD6B | par-6 family cell polarity regulator beta |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| POT1 | protection of telomeres 1 |
| PRPF4B | pre-mRNA processing factor 4B |
| PSEN2 | presenilin 2 |
| PTCH1 | patched 1 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RAB35 | RAB35, member RAS oncogene family |
| RAB5A | RAB5A, member RAS oncogene family |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| RARG | retinoic acid receptor, gamma |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RNF146 | ring finger protein 146 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPS14 | ribosomal protein S14 |
| RRM1 | ribonucleotide reductase M1 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SIRT4 | sirtuin 4 |
| SKI | SKI proto-oncogene |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SNX13 | sorting nexin 13 |
| SNX2 | sorting nexin 2 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SQLE | squalene epoxidase |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| STC1 | stanniocalcin 1 |
| SYCE1L | synaptonemal complex central element protein 1-like |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFDP1 | transcription factor Dp-1 |
| TMEM230 | transmembrane protein 230 |
| TRIM23 | tripartite motif containing 23 |
| VAMP3 | vesicle-associated membrane protein 3 |
| VAMP4 | vesicle-associated membrane protein 4 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF675 | zinc finger protein 675 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACTL8 | actin-like 8 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARRB2 | arrestin, beta 2 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BBC3 | BCL2 binding component 3 |
| CD82 | CD82 molecule |
| CTNNBL1 | catenin, beta like 1 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM46C | family with sequence similarity 46, member C |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FHOD1 | formin homology 2 domain containing 1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMOX1 | heme oxygenase 1 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT54 | intraflagellar transport 54 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KIAA0319L | KIAA0319-like |
| KIF13A | kinesin family member 13A |
| KLHL21 | kelch-like family member 21 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAMA3 | laminin, alpha 3 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MANBA | mannosidase, beta A, lysosomal |
| MAP2 | microtubule-associated protein 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MED24 | mediator complex subunit 24 |
| MFAP2 | microfibrillar-associated protein 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MUC3B | mucin 3B, cell surface associated |
| MVD | mevalonate (diphospho) decarboxylase |
| NEUROD4 | neuronal differentiation 4 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| ONECUT2 | one cut homeobox 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE12 | phosphodiesterase 12 |
| PDE8B | phosphodiesterase 8B |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLD2 | phospholipase D2 |
| PLD3 | phospholipase D family, member 3 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB36 | RAB36, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBM19 | RNA binding motif protein 19 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RIN1 | Ras and Rab interactor 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF39 | ring finger protein 39 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH2D4A | SH2 domain containing 4A |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| STEAP4 | STEAP family member 4 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TPCN1 | two pore segment channel 1 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTBK2 | tau tubulin kinase 2 |
| TWF2 | twinfilin actin binding protein 2 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UBQLN4 | ubiquilin 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR91 | WD repeat domain 91 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF34 | zinc finger protein 34 |
| ZNF747 | zinc finger protein 747 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
