tomatidine-2746 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the tomatidine-2746 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADRB2 adrenoceptor beta 2, surface
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF6B activating transcription factor 6 beta
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CA4 carbonic anhydrase IV
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CAPN5 calpain 5
CCDC57 coiled-coil domain containing 57
CCDC69 coiled-coil domain containing 69
CD160 CD160 molecule
CD70 CD70 molecule
CDC14B cell division cycle 14B
CDRT1 CMT1A duplicated region transcript 1
CERS4 ceramide synthase 4
CLCA1 chloride channel accessory 1
COL5A1 collagen, type V, alpha 1
CRAT carnitine O-acetyltransferase
CRTC1 CREB regulated transcription coactivator 1
CTSF cathepsin F
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DENND5B DENN/MADD domain containing 5B
DICER1 dicer 1, ribonuclease type III
DMTN dematin actin binding protein
DOK4 docking protein 4
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FAM184A family with sequence similarity 184, member A
FBXO41 F-box protein 41
FN1 fibronectin 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GIMAP6 GTPase, IMAP family member 6
GPC3 glypican 3
GPR15 G protein-coupled receptor 15
HAB1 B1 for mucin
HCRP1 hepatocellular carcinoma-related HCRP1
HIST1H3F histone cluster 1, H3f
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXB2 homeobox B2
ICA1 islet cell autoantigen 1, 69kDa
IL11 interleukin 11
IL1RN interleukin 1 receptor antagonist
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF4 interferon regulatory factor 4
KANK1 KN motif and ankyrin repeat domains 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
LHX2 LIM homeobox 2
LRRC14 leucine rich repeat containing 14
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK14 mitogen-activated protein kinase 14
MARK4 MAP/microtubule affinity-regulating kinase 4
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MR1 major histocompatibility complex, class I-related
MST1 macrophage stimulating 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYL10 myosin, light chain 10, regulatory
MZF1 myeloid zinc finger 1
NCR2 natural cytotoxicity triggering receptor 2
NME5 NME/NM23 family member 5
NRN1 neuritin 1
OXCT2 3-oxoacid CoA transferase 2
PCDH12 protocadherin 12
PCDHGA10 protocadherin gamma subfamily A, 10
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIGR polymeric immunoglobulin receptor
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLL polymerase (DNA directed), lambda
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIMS3 regulating synaptic membrane exocytosis 3
RORC RAR-related orphan receptor C
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
RUNX1 runt-related transcription factor 1
S100A12 S100 calcium binding protein A12
S100A9 S100 calcium binding protein A9
SH2D3A SH2 domain containing 3A
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
ST7L suppression of tumorigenicity 7 like
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYNC syncoilin, intermediate filament protein
TBX19 T-box 19
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TMC6 transmembrane channel-like 6
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TPM2 tropomyosin 2 (beta)
TRBC1 T cell receptor beta constant 1
UPK3B uroplakin 3B
VIM vimentin
XDH xanthine dehydrogenase
ZC3H7B zinc finger CCCH-type containing 7B
ZER1 zyg-11 related, cell cycle regulator
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF592 zinc finger protein 592

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
AEN apoptosis enhancing nuclease
AHDC1 AT hook, DNA binding motif, containing 1
ASB6 ankyrin repeat and SOCS box containing 6
AUNIP aurora kinase A and ninein interacting protein
BMP4 bone morphogenetic protein 4
C10ORF88 chromosome 10 open reading frame 88
C1ORF109 chromosome 1 open reading frame 109
C1ORF159 chromosome 1 open reading frame 159
CALCOCO1 calcium binding and coiled-coil domain 1
CASD1 CAS1 domain containing 1
CBX7 chromobox homolog 7
CCNE1 cyclin E1
CLASP1 cytoplasmic linker associated protein 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAL4 dynein, axonemal, light chain 4
E2F8 E2F transcription factor 8
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EPHA2 EPH receptor A2
ERCC3 excision repair cross-complementation group 3
FAM172A family with sequence similarity 172, member A
FBXL2 F-box and leucine-rich repeat protein 2
FMO4 flavin containing monooxygenase 4
FPGS folylpolyglutamate synthase
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GBP2 guanylate binding protein 2, interferon-inducible
GLCE glucuronic acid epimerase
GLTSCR1 glioma tumor suppressor candidate region gene 1
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
HIRA histone cell cycle regulator
HOXC11 homeobox C11
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IRF6 interferon regulatory factor 6
KATNBL1 katanin p80 subunit B-like 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KLHL26 kelch-like family member 26
LRP3 low density lipoprotein receptor-related protein 3
LYPD1 LY6/PLAUR domain containing 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MANBA mannosidase, beta A, lysosomal
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MFSD11 major facilitator superfamily domain containing 11
MITF microphthalmia-associated transcription factor
MNS1 meiosis-specific nuclear structural 1
MPI mannose phosphate isomerase
MYO19 myosin XIX
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NHEJ1 nonhomologous end-joining factor 1
NPY1R neuropeptide Y receptor Y1
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PARD6A par-6 family cell polarity regulator alpha
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHA6 protocadherin alpha 6
PCDHB3 protocadherin beta 3
PGPEP1 pyroglutamyl-peptidase I
PHACTR4 phosphatase and actin regulator 4
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PMCH pro-melanin-concentrating hormone
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB23 RAB23, member RAS oncogene family
RAB32 RAB32, member RAS oncogene family
RAD51AP1 RAD51 associated protein 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM7 RNA binding motif protein 7
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIC8B RIC8 guanine nucleotide exchange factor B
RPIA ribose 5-phosphate isomerase A
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH3YL1 SH3 and SYLF domain containing 1
SLC25A40 solute carrier family 25, member 40
SLC35F6 solute carrier family 35, member F6
SMAD7 SMAD family member 7
SNHG3 small nucleolar RNA host gene 3
SQRDL sulfide quinone reductase-like (yeast)
STK16 serine/threonine kinase 16
STRN striatin, calmodulin binding protein
TBC1D12 TBC1 domain family, member 12
TCTA T-cell leukemia translocation altered
TDP1 tyrosyl-DNA phosphodiesterase 1
THBS3 thrombospondin 3
TMSB15B thymosin beta 15B
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UBQLN4 ubiquilin 4
VASH2 vasohibin 2
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR76 WD repeat domain 76
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF282 zinc finger protein 282
ZNF324 zinc finger protein 324
ZNF668 zinc finger protein 668
ZNRD1-AS1 ZNRD1 antisense RNA 1