| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the tomatidine-5808 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| AMDHD2 | amidohydrolase domain containing 2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BDKRB1 | bradykinin receptor B1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BRSK2 | BR serine/threonine kinase 2 |
| CDK17 | cyclin-dependent kinase 17 |
| CDON | cell adhesion associated, oncogene regulated |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CNTN5 | contactin 5 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CTSF | cathepsin F |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| EMC3 | ER membrane protein complex subunit 3 |
| EPS8L1 | EPS8-like 1 |
| EZR | ezrin |
| FAM134B | family with sequence similarity 134, member B |
| FAM184A | family with sequence similarity 184, member A |
| FAM50B | family with sequence similarity 50, member B |
| FNDC3A | fibronectin type III domain containing 3A |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 |
| GPATCH4 | G patch domain containing 4 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GRM4 | glutamate receptor, metabotropic 4 |
| HAL | histidine ammonia-lyase |
| HOXA4 | homeobox A4 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| IQCK | IQ motif containing K |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIF5C | kinesin family member 5C |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT86 | keratin 86, type II |
| LAMA4 | laminin, alpha 4 |
| LIFR | leukemia inhibitory factor receptor alpha |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MT1M | metallothionein 1M |
| MTM1 | myotubularin 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NID2 | nidogen 2 (osteonidogen) |
| NIPAL2 | NIPA-like domain containing 2 |
| NPTXR | neuronal pentraxin receptor |
| PDLIM5 | PDZ and LIM domain 5 |
| PEX10 | peroxisomal biogenesis factor 10 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PRPF18 | pre-mRNA processing factor 18 |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| PURA | purine-rich element binding protein A |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB3B | RAB3B, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAD51 | RAD51 recombinase |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RNF122 | ring finger protein 122 |
| RUNX3 | runt-related transcription factor 3 |
| RYK | receptor-like tyrosine kinase |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMC1A | structural maintenance of chromosomes 1A |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNTG1 | syntrophin, gamma 1 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SYN2 | synapsin II |
| SYT1 | synaptotagmin I |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TBX2 | T-box 2 |
| TPMT | thiopurine S-methyltransferase |
| TSFM | Ts translation elongation factor, mitochondrial |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| TXNRD3 | thioredoxin reductase 3 |
| WDR1 | WD repeat domain 1 |
| WDR62 | WD repeat domain 62 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| YY1 | YY1 transcription factor |
| ZNF358 | zinc finger protein 358 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ATG9A | autophagy related 9A |
| ATP13A2 | ATPase type 13A2 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BMP15 | bone morphogenetic protein 15 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDH7 | cadherin 7, type 2 |
| CHKB | choline kinase beta |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CNPY3 | canopy FGF signaling regulator 3 |
| COBL | cordon-bleu WH2 repeat protein |
| COMMD9 | COMM domain containing 9 |
| COQ4 | coenzyme Q4 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DUSP8 | dual specificity phosphatase 8 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGF | epidermal growth factor |
| ERF | Ets2 repressor factor |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FADS2 | fatty acid desaturase 2 |
| FAM193B | family with sequence similarity 193, member B |
| FAM53B | family with sequence similarity 53, member B |
| FGGY | FGGY carbohydrate kinase domain containing |
| FOXA1 | forkhead box A1 |
| GAB2 | GRB2-associated binding protein 2 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AI | histone cluster 1, H2ai |
| HMOX1 | heme oxygenase 1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL17RB | interleukin 17 receptor B |
| IRF9 | interferon regulatory factor 9 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LOC100127972 | uncharacterized LOC100127972 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRRC42 | leucine rich repeat containing 42 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MED22 | mediator complex subunit 22 |
| MOB3B | MOB kinase activator 3B |
| MPHOSPH6 | M-phase phosphoprotein 6 |
| MST1R | macrophage stimulating 1 receptor |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NAG18 | NAG18 mRNA |
| NARFL | nuclear prelamin A recognition factor-like |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORC1 | origin recognition complex, subunit 1 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PYCARD | PYD and CARD domain containing |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| S100P | S100 calcium binding protein P |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SPAG4 | sperm associated antigen 4 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| THAP4 | THAP domain containing 4 |
| TMEM104 | transmembrane protein 104 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TNNI3 | troponin I type 3 (cardiac) |
| TNRC6B | trinucleotide repeat containing 6B |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TTC17 | tetratricopeptide repeat domain 17 |
| TTI2 | TELO2 interacting protein 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VEGFB | vascular endothelial growth factor B |
| VWA9 | von Willebrand factor A domain containing 9 |
| WDR76 | WD repeat domain 76 |
| ZNF552 | zinc finger protein 552 |
| ZXDC | ZXD family zinc finger C |
