tonsillitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An upper respiratory tract disease which involves inflammation of the tonsils resulting from bacterial (Group A streptococcus) and viral (Epstein-Barr virus, adenovirus) infections. Symptoms include a severe sore throat (which may be experienced as referred pain to the ears), painful/difficult swallowing, coughing, headache, myalgia (muscle aches), fever and chills. Tonsillitis is characterized by signs of red, swollen tonsils which may have a purulent exudative coating of white patches (i.e. pus). Swelling of the cheeks and neck may occur. (Human Disease Ontology, DOID_10456)
Similar Terms
Downloads & Tools

Genes

146 genes co-occuring with the disease tonsillitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
KSR1 kinase suppressor of ras 1 1.66015
CD79A CD79a molecule, immunoglobulin-associated alpha 1.58849
HSF4 heat shock transcription factor 4 1.48252
DEFB113 defensin, beta 113 1.44913
PDZD11 PDZ domain containing 11 1.21262
CRP C-reactive protein, pentraxin-related 1.19014
PGPEP1 pyroglutamyl-peptidase I 1.17937
DEFA4 defensin, alpha 4, corticostatin 1.17421
C1GALT1C1 C1GALT1-specific chaperone 1 1.13882
DNPEP aspartyl aminopeptidase 1.02735
LEAP2 liver expressed antimicrobial peptide 2 0.981373
CD4 CD4 molecule 0.95996
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.951187
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 0.921736
HTRA3 HtrA serine peptidase 3 0.918848
CD19 CD19 molecule 0.901978
SKA2 spindle and kinetochore associated complex subunit 2 0.88393
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 0.872462
ETV2 ets variant 2 0.853631
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.850354
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 0.846259
TRIM39 tripartite motif containing 39 0.832329
ZNF410 zinc finger protein 410 0.825358
NBPF1 neuroblastoma breakpoint family, member 1 0.815924
FLNA filamin A, alpha 0.76921
EDC3 enhancer of mRNA decapping 3 0.754934
TLR10 toll-like receptor 10 0.731786
ANPEP alanyl (membrane) aminopeptidase 0.715618
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.706754
LYZ lysozyme 0.681096
LTA lymphotoxin alpha 0.677903
CXCL6 chemokine (C-X-C motif) ligand 6 0.675909
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like 0.663578
SKA1 spindle and kinetochore associated complex subunit 1 0.659611
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 0.650903
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.631205
PRCP prolylcarboxypeptidase (angiotensinase C) 0.580439
SPEG SPEG complex locus 0.567609
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.565277
DEFB1 defensin, beta 1 0.561392
CFP complement factor properdin 0.556732
CD48 CD48 molecule 0.556732
IL1A interleukin 1, alpha 0.553239
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 0.551686
CYSLTR2 cysteinyl leukotriene receptor 2 0.540829
CLDN14 claudin 14 0.538893
PREP prolyl endopeptidase 0.533861
RXRB retinoid X receptor, beta 0.520731
PDZD4 PDZ domain containing 4 0.519961
STPG1 sperm-tail PG-rich repeat containing 1 0.508808
PSPH phosphoserine phosphatase 0.506507
LOR loricrin 0.483224
SOD2 superoxide dismutase 2, mitochondrial 0.477909
GAN gigaxonin 0.477151
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 0.474877
HIPK2 homeodomain interacting protein kinase 2 0.473361
EPRS glutamyl-prolyl-tRNA synthetase 0.456355
HP haptoglobin 0.451454
HPR haptoglobin-related protein 0.445052
TPI1 triosephosphate isomerase 1 0.412779
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.40904
PER3 period circadian clock 3 0.405305
NUP153 nucleoporin 153kDa 0.401199
DPEP1 dipeptidase 1 (renal) 0.392257
NCAM1 neural cell adhesion molecule 1 0.390025
CXCL5 chemokine (C-X-C motif) ligand 5 0.387423
SHF Src homology 2 domain containing F 0.378885
TLR1 toll-like receptor 1 0.374809
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.366301
ARF1 ADP-ribosylation factor 1 0.364824
TGFB1 transforming growth factor, beta 1 0.34384
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.339073
IL1B interleukin 1, beta 0.338341
MYBPC1 myosin binding protein C, slow type 0.337975
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 0.334315
DPP4 dipeptidyl-peptidase 4 0.331391
IGLV3-10 immunoglobulin lambda variable 3-10 0.323002
PDLIM7 PDZ and LIM domain 7 (enigma) 0.318999
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.313552
CGB7 chorionic gonadotropin, beta polypeptide 7 0.301615
CGB5 chorionic gonadotropin, beta polypeptide 5 0.300173
NUTM1 NUT midline carcinoma, family member 1 0.294053
LTA4H leukotriene A4 hydrolase 0.28616
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.283297
TLR9 toll-like receptor 9 0.28294
FRS2 fibroblast growth factor receptor substrate 2 0.280082
CGB chorionic gonadotropin, beta polypeptide 0.277227
CGB8 chorionic gonadotropin, beta polypeptide 8 0.276514
LY75 lymphocyte antigen 75 0.276158
IL7R interleukin 7 receptor 0.27153
CD40 CD40 molecule, TNF receptor superfamily member 5 0.267267
TOB1 transducer of ERBB2, 1 0.261599
THEM4 thioesterase superfamily member 4 0.257005
NPEPPS aminopeptidase puromycin sensitive 0.249257
MASP2 mannan-binding lectin serine peptidase 2 0.248554
YME1L1 YME1-like 1 ATPase 0.246799
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.245046
PIGR polymeric immunoglobulin receptor 0.241196
IL4 interleukin 4 0.238054
KMT2A lysine (K)-specific methyltransferase 2A 0.237357
CRYGD crystallin, gamma D 0.236312
C5 complement component 5 0.23492
ASPH aspartate beta-hydroxylase 0.234225
LTC4S leukotriene C4 synthase 0.233183
LTF lactotransferrin 0.231102
CYSLTR1 cysteinyl leukotriene receptor 1 0.230063
ADGRV1 adhesion G protein-coupled receptor V1 0.227297
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.224196
ALB albumin 0.222479
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 0.213959
MID2 midline 2 0.212608
CAT catalase 0.210925
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.208579
CAV2 caveolin 2 0.208245
NT5E 5'-nucleotidase, ecto (CD73) 0.207245
TNF tumor necrosis factor 0.205585
BRD4 bromodomain containing 4 0.204593
CAMP cathelicidin antimicrobial peptide 0.203604
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.202946
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.201635
DEFB4A defensin, beta 4A 0.199681
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.197742
NELFCD negative elongation factor complex member C/D 0.196459
CD68 CD68 molecule 0.195183
SIK1 salt-inducible kinase 1 0.1936
LAP3 leucine aminopeptidase 3 0.191097
NOVA2 neuro-oncological ventral antigen 2 0.188022
GPX1 glutathione peroxidase 1 0.185612
CD27 CD27 molecule 0.183248
MAP2K3 mitogen-activated protein kinase kinase 3 0.182375
TLR2 toll-like receptor 2 0.181222
S100A7 S100 calcium binding protein A7 0.177576
CD38 CD38 molecule 0.173832
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.173057
CD59 CD59 molecule, complement regulatory protein 0.172799
RER1 retention in endoplasmic reticulum sorting receptor 1 0.170789
BIN1 bridging integrator 1 0.170544
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.167452
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.167224
IRAK1 interleukin-1 receptor-associated kinase 1 0.167224
CD8B CD8b molecule 0.166095
IL2RA interleukin 2 receptor, alpha 0.165217
PLG plasminogen 0.163523
PRRC2A proline-rich coiled-coil 2A 0.162908
WARS tryptophanyl-tRNA synthetase 0.162306
CD70 CD70 molecule 0.158778