tonsillitis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An upper respiratory tract disease which involves inflammation of the tonsils resulting from bacterial (Group A streptococcus) and viral (Epstein-Barr virus, adenovirus) infections. Symptoms include a severe sore throat (which may be experienced as referred pain to the ears), painful/difficult swallowing, coughing, headache, myalgia (muscle aches), fever and chills. Tonsillitis is characterized by signs of red, swollen tonsils which may have a purulent exudative coating of white patches (i.e. pus). Swelling of the cheeks and neck may occur. (Human Disease Ontology, DOID_10456)
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Genes

13 genes co-occuring with the biological term tonsillitis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADA adenosine deaminase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CX3CR1 chemokine (C-X3-C motif) receptor 1
DPP4 dipeptidyl-peptidase 4
FASLG Fas ligand (TNF superfamily, member 6)
GPX1 glutathione peroxidase 1
ICAM1 intercellular adhesion molecule 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
RXRB retinoid X receptor, beta
S100A7 S100 calcium binding protein A7
SOD2 superoxide dismutase 2, mitochondrial