| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the topiramate-915 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ADCK2 | aarF domain containing kinase 2 |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APC | adenomatous polyposis coli |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| BCORL1 | BCL6 corepressor-like 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CCNT2 | cyclin T2 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDC25C | cell division cycle 25C |
| CEP131 | centrosomal protein 131kDa |
| CEP290 | centrosomal protein 290kDa |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DCX | doublecortin |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DIAPH1 | diaphanous-related formin 1 |
| FANCA | Fanconi anemia, complementation group A |
| FAS | Fas cell surface death receptor |
| FOXJ3 | forkhead box J3 |
| FZD1 | frizzled class receptor 1 |
| GID4 | GID complex subunit 4 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GOLGA2 | golgin A2 |
| GOLGA4 | golgin A4 |
| GON4L | gon-4-like (C. elegans) |
| GSK3A | glycogen synthase kinase 3 alpha |
| HFE | hemochromatosis |
| HIST1H4H | histone cluster 1, H4h |
| INADL | InaD-like (Drosophila) |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0894 | KIAA0894 protein |
| KLF11 | Kruppel-like factor 11 |
| KLHL21 | kelch-like family member 21 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC399491 | |
| MAP4 | microtubule-associated protein 4 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MUC1 | mucin 1, cell surface associated |
| NAAA | N-acylethanolamine acid amidase |
| NCAM2 | neural cell adhesion molecule 2 |
| NEBL | nebulette |
| NF1 | neurofibromin 1 |
| NFATC2IP | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein |
| NFIB | nuclear factor I/B |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPEPPS | aminopeptidase puromycin sensitive |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLK4 | polo-like kinase 4 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 |
| RABGAP1 | RAB GTPase activating protein 1 |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF216 | ring finger protein 216 |
| RPS28 | ribosomal protein S28 |
| SCAI | suppressor of cancer cell invasion |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STK11 | serine/threonine kinase 11 |
| SUMO1 | small ubiquitin-like modifier 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| THBS3 | thrombospondin 3 |
| TM2D1 | TM2 domain containing 1 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| URGCP | upregulator of cell proliferation |
| VLDLR | very low density lipoprotein receptor |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WNK1 | WNK lysine deficient protein kinase 1 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF14 | zinc finger protein 14 |
| ZNF227 | zinc finger protein 227 |
| ZNF268 | zinc finger protein 268 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ACTL8 | actin-like 8 |
| AGO1 | argonaute RISC catalytic component 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKRD40 | ankyrin repeat domain 40 |
| ANPEP | alanyl (membrane) aminopeptidase |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5AR2 | complement component 5a receptor 2 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK20 | cyclin-dependent kinase 20 |
| CENPO | centromere protein O |
| CHML | choroideremia-like (Rab escort protein 2) |
| CORT | cortistatin |
| CPTP | ceramide-1-phosphate transfer protein |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTC1 | CTS telomere maintenance complex component 1 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DMTN | dematin actin binding protein |
| DNM1 | dynamin 1 |
| DSE | dermatan sulfate epimerase |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| FAM53B | family with sequence similarity 53, member B |
| FBRS | fibrosin |
| FLJ22184 | |
| FLT4 | fms-related tyrosine kinase 4 |
| FOSL1 | FOS-like antigen 1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| HDAC7 | histone deacetylase 7 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| IFT81 | intraflagellar transport 81 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KDM8 | lysine (K)-specific demethylase 8 |
| KRT15 | keratin 15, type I |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LRRC49 | leucine rich repeat containing 49 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MCOLN1 | mucolipin 1 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| NAG18 | NAG18 mRNA |
| NLRX1 | NLR family member X1 |
| OFD1 | oral-facial-digital syndrome 1 |
| PCDHB3 | protocadherin beta 3 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PMP22 | peripheral myelin protein 22 |
| POLH | polymerase (DNA directed), eta |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRPH | peripherin |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB33B | RAB33B, member RAS oncogene family |
| RAPSN | receptor-associated protein of the synapse |
| RBL1 | retinoblastoma-like 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF39 | ring finger protein 39 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STX5 | syntaxin 5 |
| TDRD1 | tudor domain containing 1 |
| TGFB3 | transforming growth factor, beta 3 |
| TMEM51 | transmembrane protein 51 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USB1 | U6 snRNA biogenesis 1 |
| VEGFC | vascular endothelial growth factor C |
| WDR91 | WD repeat domain 91 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF34 | zinc finger protein 34 |
| ZNF551 | zinc finger protein 551 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
