topiramate Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine. (Chemical Entities of Biological Interest Ontology, CHEBI_63631)
External Link http://ctdbase.org/detail.go?type=chem&acc=C052342
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Genes

25 genes/proteins interacting with the chemical topiramate from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADIPOQ adiponectin, C1Q and collagen domain containing
CA1 carbonic anhydrase I
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CA3 carbonic anhydrase III
CALCA calcitonin-related polypeptide alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GLUL glutamate-ammonia ligase
GRIK1 glutamate receptor, ionotropic, kainate 1
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
NOS2 nitric oxide synthase 2, inducible
NPY neuropeptide Y
NR1I2 nuclear receptor subfamily 1, group I, member 2
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7