torc1 Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p. (Gene Ontology, GO_0031931)
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Genes

18 genes co-occuring with the biological term torc1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
AKT1	v-akt murine thymoma viral oncogene homolog 1
BRAF	B-Raf proto-oncogene, serine/threonine kinase
BRSK2	BR serine/threonine kinase 2
CRTC1	CREB regulated transcription coactivator 1
EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1
FLCN	folliculin
LDHB	lactate dehydrogenase B
MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPKAP1	mitogen-activated protein kinase associated protein 1
MTOR	mechanistic target of rapamycin (serine/threonine kinase)
PTEN	phosphatase and tensin homolog
RAB5A	RAB5A, member RAS oncogene family
RHEB	Ras homolog enriched in brain
RICTOR	RPTOR independent companion of MTOR, complex 2
RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1
TSC1	tuberous sclerosis 1
TSC2	tuberous sclerosis 2
WIPI1	WD repeat domain, phosphoinositide interacting 1