torc2 Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p. (Gene Ontology, GO_0031932)
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Genes

10 genes co-occuring with the biological term torc2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
AKT1	v-akt murine thymoma viral oncogene homolog 1
CREB1	cAMP responsive element binding protein 1
CRTC2	CREB regulated transcription coactivator 2
MAPKAP1	mitogen-activated protein kinase associated protein 1
MTOR	mechanistic target of rapamycin (serine/threonine kinase)
NONO	non-POU domain containing, octamer-binding
PTEN	phosphatase and tensin homolog
RICTOR	RPTOR independent companion of MTOR, complex 2
TAF5L	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TCL1A	T-cell leukemia/lymphoma 1A