tp63_16885358_squamous_epithelia_lof_human_gpl570_gds2088 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS2088
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Genes

173 genes differentially expressed following the tp63_16885358_squamous_epithelia_lof_human_gpl570_gds2088 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
PSG1 pregnancy specific beta-1-glycoprotein 1 0.219484
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.216083
BCAS1 breast carcinoma amplified sequence 1 0.205046
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 0.203998
MAATS1 MYCBP-associated, testis expressed 1 0.20232
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta 0.20088
MFSD7 major facilitator superfamily domain containing 7 0.198219
RIF1 replication timing regulatory factor 1 0.194531
MYH11 myosin, heavy chain 11, smooth muscle 0.19268
UNC13C unc-13 homolog C (C. elegans) 0.183673
EVX1 even-skipped homeobox 1 0.180104
CLEC4D C-type lectin domain family 4, member D 0.179629
CCDC85A coiled-coil domain containing 85A 0.171165
PTCHD2 patched domain containing 2 0.167106
HIST1H2AJ histone cluster 1, H2aj 0.161669
AFP alpha-fetoprotein 0.16093
RAB11FIP4 RAB11 family interacting protein 4 (class II) 0.159253
HLA-F-AS1 HLA-F antisense RNA 1 0.153089
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16 0.152915
TAT tyrosine aminotransferase 0.148378
HIST1H2BD histone cluster 1, H2bd 0.146093
C6ORF165 chromosome 6 open reading frame 165 0.14472
BAIAP2-AS1 BAIAP2 antisense RNA 1 (head to head) 0.14152
SEPT2 septin 2 0.138118
ZSWIM8 zinc finger, SWIM-type containing 8 0.130289
NOL7 nucleolar protein 7, 27kDa 0.129285
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.125794
HCRTR2 hypocretin (orexin) receptor 2 0.121333
ALB albumin 0.119639
TMEM51-AS1 TMEM51 antisense RNA 1 0.114696
SNORA65 small nucleolar RNA, H/ACA box 65 0.109479
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 0.109096
MDS2 myelodysplastic syndrome 2 translocation associated 0.105216
FAM182A family with sequence similarity 182, member A 0.103148
VASH2 vasohibin 2 0.102708
TESK2 testis-specific kinase 2 0.102435
GPM6B glycoprotein M6B 0.102193
PCDHB4 protocadherin beta 4 0.101422
RNF175 ring finger protein 175 0.099503
SLC26A11 solute carrier family 26 (anion exchanger), member 11 0.095345
ESRG embryonic stem cell related (non-protein coding) 0.094523
FOXJ2 forkhead box J2 0.090347
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.082489
KIF1C kinesin family member 1C 0.078889
PNPLA2 patatin-like phospholipase domain containing 2 0.078631
MIB2 mindbomb E3 ubiquitin protein ligase 2 0.077281
ISYNA1 inositol-3-phosphate synthase 1 0.074071
PCAT4 prostate cancer associated transcript 4 (non-protein coding) 0.073148
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.070003
BHLHE22 basic helix-loop-helix family, member e22 0.065219
TMEM26 transmembrane protein 26 0.062269
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.060069
CLEC10A C-type lectin domain family 10, member A 0.057761
PPP1R3B protein phosphatase 1, regulatory subunit 3B 0.052712
SH3BP2 SH3-domain binding protein 2 0.048912
ADAMTSL5 ADAMTS-like 5 0.048736
ERBB3 erb-b2 receptor tyrosine kinase 3 0.047163
WDTC1 WD and tetratricopeptide repeats 1 0.042321
SIRPA signal-regulatory protein alpha 0.04104
WDR1 WD repeat domain 1 0.030599
TMC6 transmembrane channel-like 6 0.029973
SHISA9 shisa family member 9 0.024386
ADH6 alcohol dehydrogenase 6 (class V) 0.023434
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.021225
NMRAL1 NmrA-like family domain containing 1 0.020287
CADM3 cell adhesion molecule 3 0.019871
DNAH1 dynein, axonemal, heavy chain 1 0.018238
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 0.017288
IFNA6 interferon, alpha 6 0.012488
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 0.005322
CELF5 CUGBP, Elav-like family member 5 0.004189
CTBP1-AS2 CTBP1 antisense RNA 2 (head to head) 0.003065
ADAMTSL1 ADAMTS-like 1 0.003017
TMEM108 transmembrane protein 108 0.002634
AKAP12 A kinase (PRKA) anchor protein 12 0.001188

decreased expression

Symbol Name Standardized Value
WDR73 WD repeat domain 73 -1.28631
WDR55 WD repeat domain 55 -1.27935
ENOPH1 enolase-phosphatase 1 -1.19598
PLA2G1B phospholipase A2, group IB (pancreas) -1.18022
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 -1.14954
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 -1.12809
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -1.09988
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 -1.09791
C20ORF196 chromosome 20 open reading frame 196 -1.07637
SEPT7 septin 7 -1.03964
SPRYD3 SPRY domain containing 3 -1.03767
TERF2 telomeric repeat binding factor 2 -1.02527
FAHD2A fumarylacetoacetate hydrolase domain containing 2A -1.0106
GINS3 GINS complex subunit 3 (Psf3 homolog) -0.993273
NOX1 NADPH oxidase 1 -0.990241
EGLN2 egl-9 family hypoxia-inducible factor 2 -0.965005
SIM1 single-minded family bHLH transcription factor 1 -0.947431
LATS1 large tumor suppressor kinase 1 -0.937593
ARHGAP22 Rho GTPase activating protein 22 -0.936507
FBXO30 F-box protein 30 -0.932547
HTRA2 HtrA serine peptidase 2 -0.91745
LINC00923 long intergenic non-protein coding RNA 923 -0.909418
METTL5 methyltransferase like 5 -0.903715
PECR peroxisomal trans-2-enoyl-CoA reductase -0.881739
LRP11 low density lipoprotein receptor-related protein 11 -0.854621
FAM63B family with sequence similarity 63, member B -0.848415
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 -0.831513
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.803579
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 -0.787805
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.750252
LOC100133862 -0.74742
CCDC61 coiled-coil domain containing 61 -0.711616
FAM92A1 family with sequence similarity 92, member A1 -0.700605
DKC1 dyskeratosis congenita 1, dyskerin -0.659867
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -0.645415
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.625505
LOC283112 uncharacterized LOC283112 -0.617697
TIAM1 T-cell lymphoma invasion and metastasis 1 -0.616428
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 -0.578082
KRTAP19-1 keratin associated protein 19-1 -0.568285
SF3B5 splicing factor 3b, subunit 5, 10kDa -0.556178
TACC2 transforming, acidic coiled-coil containing protein 2 -0.556071
SPATS2 spermatogenesis associated, serine-rich 2 -0.539831
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) -0.537274
FBXO2 F-box protein 2 -0.533707
FAM109A family with sequence similarity 109, member A -0.533364
TBC1D24 TBC1 domain family, member 24 -0.529516
PDE4DIP phosphodiesterase 4D interacting protein -0.529037
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) -0.525652
VWA8 von Willebrand factor A domain containing 8 -0.519119
LAG3 lymphocyte-activation gene 3 -0.518071
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) -0.517798
ACBD6 acyl-CoA binding domain containing 6 -0.513776
DUSP9 dual specificity phosphatase 9 -0.512314
MTTP microsomal triglyceride transfer protein -0.508791
GKAP1 G kinase anchoring protein 1 -0.504528
HELB helicase (DNA) B -0.49074
RGR retinal G protein coupled receptor -0.473733
IL21R interleukin 21 receptor -0.470274
SFSWAP splicing factor, suppressor of white-apricot family -0.467478
TECTA tectorin alpha -0.459347
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.454544
C1ORF86 chromosome 1 open reading frame 86 -0.449543
HLA-DOB major histocompatibility complex, class II, DO beta -0.44904
HPS4 Hermansky-Pudlak syndrome 4 -0.446866
MIER3 mesoderm induction early response 1, family member 3 -0.439503
INPP1 inositol polyphosphate-1-phosphatase -0.4379
CEP120 centrosomal protein 120kDa -0.436154
ARL15 ADP-ribosylation factor-like 15 -0.058287
STAMBP STAM binding protein -0.05793
SIRPB1 signal-regulatory protein beta 1 -0.055632
RGS22 regulator of G-protein signaling 22 -0.054484
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.050343
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 -0.049523
COL4A5 collagen, type IV, alpha 5 -0.048311
MCAM melanoma cell adhesion molecule -0.046502
INTS4 integrator complex subunit 4 -0.044882
TM9SF3 transmembrane 9 superfamily member 3 -0.044261
CXCR2 chemokine (C-X-C motif) receptor 2 -0.04134
APOA2 apolipoprotein A-II -0.03904
LINC00052 long intergenic non-protein coding RNA 52 -0.034476
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.031299
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 -0.028221
LARGE like-glycosyltransferase -0.019568
OPRM1 opioid receptor, mu 1 -0.019318
NUP88 nucleoporin 88kDa -0.018481
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 -0.013817
POSTN periostin, osteoblast specific factor -0.011515
ARG1 arginase 1 -0.010733
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 -0.010245
TMEM19 transmembrane protein 19 -0.009457
DENND1B DENN/MADD domain containing 1B -0.009134
FAM178A family with sequence similarity 178, member A -0.007371
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 -0.007324
TRPV2 transient receptor potential cation channel, subfamily V, member 2 -0.007091
XPO1 exportin 1 -0.007068
TWIST2 twist family bHLH transcription factor 2 -0.006301
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.004716