| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the tracazolate-7339 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| AP3S2 | adaptor-related protein complex 3, sigma 2 subunit |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATF3 | activating transcription factor 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC28B | coiled-coil domain containing 28B |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DUSP1 | dual specificity phosphatase 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EGR1 | early growth response 1 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| ETV5 | ets variant 5 |
| FAM120C | family with sequence similarity 120C |
| FAM184A | family with sequence similarity 184, member A |
| FAM214B | family with sequence similarity 214, member B |
| FASTKD2 | FAST kinase domains 2 |
| FBXL8 | F-box and leucine-rich repeat protein 8 |
| FRK | fyn-related Src family tyrosine kinase |
| GAMT | guanidinoacetate N-methyltransferase |
| GM2A | GM2 ganglioside activator |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GOSR1 | golgi SNAP receptor complex member 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HBEGF | heparin-binding EGF-like growth factor |
| HBS1L | HBS1-like translational GTPase |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HLA-C | major histocompatibility complex, class I, C |
| HMOX1 | heme oxygenase 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INHBE | inhibin, beta E |
| IQCG | IQ motif containing G |
| KLF6 | Kruppel-like factor 6 |
| KRT13 | keratin 13, type I |
| LMBR1L | limb development membrane protein 1-like |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MSI1 | musashi RNA-binding protein 1 |
| NF1 | neurofibromin 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PCGF3 | polycomb group ring finger 3 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PML | promyelocytic leukemia |
| POLL | polymerase (DNA directed), lambda |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRDM12 | PR domain containing 12 |
| PTK6 | protein tyrosine kinase 6 |
| PXN | paxillin |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB30 | RAB30, member RAS oncogene family |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RFPL2 | ret finger protein-like 2 |
| RHBDD3 | rhomboid domain containing 3 |
| RND1 | Rho family GTPase 1 |
| RRAGD | Ras-related GTP binding D |
| RTN2 | reticulon 2 |
| SBF1 | SET binding factor 1 |
| SECTM1 | secreted and transmembrane 1 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SRCAP | Snf2-related CREBBP activator protein |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SUGP1 | SURP and G patch domain containing 1 |
| TBC1D5 | TBC1 domain family, member 5 |
| TBKBP1 | TBK1 binding protein 1 |
| TMCO3 | transmembrane and coiled-coil domains 3 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| USP22 | ubiquitin specific peptidase 22 |
| VEGFA | vascular endothelial growth factor A |
| WAS | Wiskott-Aldrich syndrome |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ABHD17B | abhydrolase domain containing 17B |
| ACYP2 | acylphosphatase 2, muscle type |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARMC6 | armadillo repeat containing 6 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATP11B | ATPase, class VI, type 11B |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMP4 | bone morphogenetic protein 4 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| CCDC85C | coiled-coil domain containing 85C |
| CCDC94 | coiled-coil domain containing 94 |
| CDCA8 | cell division cycle associated 8 |
| CIC | capicua transcriptional repressor |
| CRBN | cereblon |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DACH1 | dachshund family transcription factor 1 |
| DYSF | dysferlin |
| EAF2 | ELL associated factor 2 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM131A | family with sequence similarity 131, member A |
| FGGY | FGGY carbohydrate kinase domain containing |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXA1 | forkhead box A1 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXC13 | homeobox C13 |
| HPN | hepsin |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| LHX1 | LIM homeobox 1 |
| LMNB1 | lamin B1 |
| MANEA | mannosidase, endo-alpha |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL44 | mitochondrial ribosomal protein L44 |
| NEK11 | NIMA-related kinase 11 |
| NPY1R | neuropeptide Y receptor Y1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NXPH4 | neurexophilin 4 |
| OLFML2A | olfactomedin-like 2A |
| OTUD3 | OTU deubiquitinase 3 |
| PCDHB3 | protocadherin beta 3 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDZK1 | PDZ domain containing 1 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PMM1 | phosphomannomutase 1 |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| PRKX | protein kinase, X-linked |
| RAB32 | RAB32, member RAS oncogene family |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RANGRF | RAN guanine nucleotide release factor |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCHIP1 | schwannomin interacting protein 1 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC38A10 | solute carrier family 38, member 10 |
| SLC46A3 | solute carrier family 46, member 3 |
| SNAI2 | snail family zinc finger 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMC7 | transmembrane channel-like 7 |
| TMEM121 | transmembrane protein 121 |
| TMEM209 | transmembrane protein 209 |
| TSPAN1 | tetraspanin 1 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USP36 | ubiquitin specific peptidase 36 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WWC2 | WW and C2 domain containing 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF16 | zinc finger protein 16 |
| ZNF205 | zinc finger protein 205 |
| ZNF219 | zinc finger protein 219 |
| ZNF324 | zinc finger protein 324 |
| ZNF432 | zinc finger protein 432 |
| ZNF506 | zinc finger protein 506 |
| ZNF573 | zinc finger protein 573 |
| ZNF574 | zinc finger protein 574 |
| ZNF701 | zinc finger protein 701 |
| ZNF747 | zinc finger protein 747 |