tracazolate-7339 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the tracazolate-7339 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARR3 arrestin 3, retinal (X-arrestin)
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATF3 activating transcription factor 3
BTF3P11 basic transcription factor 3 pseudogene 11
C2ORF27A chromosome 2 open reading frame 27A
C8ORF60 chromosome 8 open reading frame 60
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC28B coiled-coil domain containing 28B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL1A1 collagen, type I, alpha 1
CRELD1 cysteine-rich with EGF-like domains 1
CTNS cystinosin, lysosomal cystine transporter
CYLD cylindromatosis (turban tumor syndrome)
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DUSP1 dual specificity phosphatase 1
EGFL7 EGF-like-domain, multiple 7
EGR1 early growth response 1
EHBP1L1 EH domain binding protein 1-like 1
ERCC2 excision repair cross-complementation group 2
ETV5 ets variant 5
FAM120C family with sequence similarity 120C
FAM184A family with sequence similarity 184, member A
FAM214B family with sequence similarity 214, member B
FASTKD2 FAST kinase domains 2
FBXL8 F-box and leucine-rich repeat protein 8
FRK fyn-related Src family tyrosine kinase
GAMT guanidinoacetate N-methyltransferase
GM2A GM2 ganglioside activator
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOSR1 golgi SNAP receptor complex member 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HBEGF heparin-binding EGF-like growth factor
HBS1L HBS1-like translational GTPase
HCRP1 hepatocellular carcinoma-related HCRP1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HLA-C major histocompatibility complex, class I, C
HMOX1 heme oxygenase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INHBE inhibin, beta E
IQCG IQ motif containing G
KLF6 Kruppel-like factor 6
KRT13 keratin 13, type I
LMBR1L limb development membrane protein 1-like
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MSI1 musashi RNA-binding protein 1
NF1 neurofibromin 1
OASL 2'-5'-oligoadenylate synthetase-like
OSGIN1 oxidative stress induced growth inhibitor 1
PCGF3 polycomb group ring finger 3
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRDM12 PR domain containing 12
PTK6 protein tyrosine kinase 6
PXN paxillin
PYCRL pyrroline-5-carboxylate reductase-like
RAB30 RAB30, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RFPL2 ret finger protein-like 2
RHBDD3 rhomboid domain containing 3
RND1 Rho family GTPase 1
RRAGD Ras-related GTP binding D
RTN2 reticulon 2
SBF1 SET binding factor 1
SECTM1 secreted and transmembrane 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOS2 son of sevenless homolog 2 (Drosophila)
SPATS2L spermatogenesis associated, serine-rich 2-like
SRCAP Snf2-related CREBBP activator protein
SRSF7 serine/arginine-rich splicing factor 7
SUGP1 SURP and G patch domain containing 1
TBC1D5 TBC1 domain family, member 5
TBKBP1 TBK1 binding protein 1
TMCO3 transmembrane and coiled-coil domains 3
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNK1 tyrosine kinase, non-receptor, 1
TRAK1 trafficking protein, kinesin binding 1
USP22 ubiquitin specific peptidase 22
VEGFA vascular endothelial growth factor A
WAS Wiskott-Aldrich syndrome
XYLB xylulokinase homolog (H. influenzae)
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD17B abhydrolase domain containing 17B
ACYP2 acylphosphatase 2, muscle type
ARHGAP11A Rho GTPase activating protein 11A
ARMC6 armadillo repeat containing 6
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD3A ATPase family, AAA domain containing 3A
ATP11B ATPase, class VI, type 11B
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BACE1 beta-site APP-cleaving enzyme 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMP4 bone morphogenetic protein 4
BTF3P12 basic transcription factor 3 pseudogene 12
CCDC85C coiled-coil domain containing 85C
CCDC94 coiled-coil domain containing 94
CDCA8 cell division cycle associated 8
CIC capicua transcriptional repressor
CRBN cereblon
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DACH1 dachshund family transcription factor 1
DYSF dysferlin
EAF2 ELL associated factor 2
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EFHC1 EF-hand domain (C-terminal) containing 1
EXD3 exonuclease 3'-5' domain containing 3
FAM131A family with sequence similarity 131, member A
FGGY FGGY carbohydrate kinase domain containing
FKBP10 FK506 binding protein 10, 65 kDa
FLT4 fms-related tyrosine kinase 4
FOXA1 forkhead box A1
GAREM GRB2 associated, regulator of MAPK1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC13 homeobox C13
HPN hepsin
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
LHX1 LIM homeobox 1
LMNB1 lamin B1
MANEA mannosidase, endo-alpha
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBIP MAP3K12 binding inhibitory protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFSD11 major facilitator superfamily domain containing 11
MFSD12 major facilitator superfamily domain containing 12
MORC3 MORC family CW-type zinc finger 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL44 mitochondrial ribosomal protein L44
NEK11 NIMA-related kinase 11
NPY1R neuropeptide Y receptor Y1
NT5DC3 5'-nucleotidase domain containing 3
NXPH4 neurexophilin 4
OLFML2A olfactomedin-like 2A
OTUD3 OTU deubiquitinase 3
PCDHB3 protocadherin beta 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PDZK1 PDZ domain containing 1
PELI1 pellino E3 ubiquitin protein ligase 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PMM1 phosphomannomutase 1
POLR1E polymerase (RNA) I polypeptide E, 53kDa
PRKX protein kinase, X-linked
RAB32 RAB32, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RANGRF RAN guanine nucleotide release factor
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCHIP1 schwannomin interacting protein 1
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC38A10 solute carrier family 38, member 10
SLC46A3 solute carrier family 46, member 3
SNAI2 snail family zinc finger 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMC7 transmembrane channel-like 7
TMEM121 transmembrane protein 121
TMEM209 transmembrane protein 209
TSPAN1 tetraspanin 1
TUBGCP5 tubulin, gamma complex associated protein 5
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP36 ubiquitin specific peptidase 36
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WWC2 WW and C2 domain containing 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZMAT5 zinc finger, matrin-type 5
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF324 zinc finger protein 324
ZNF432 zinc finger protein 432
ZNF506 zinc finger protein 506
ZNF573 zinc finger protein 573
ZNF574 zinc finger protein 574
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747