trachoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A commensal bacterial infectious disease that results_in infection located_in eye, has_material_basis_in Chlamydia trachomatis (A, B, Ba and C serovars), which is transmitted_by contact with eye discharge from the infected person and transmitted_by congenital method. The infection causes eyelid to turn inward which makes eyelashes to scratch the cornea. (Human Disease Ontology, DOID_11265)
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Genes

96 genes co-occuring with the disease trachoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.37512
TEPP testis, prostate and placenta expressed 1.19704
S100A7 S100 calcium binding protein A7 1.11561
GOLGA5 golgin A5 1.08244
IER2 immediate early response 2 1.05303
CD79A CD79a molecule, immunoglobulin-associated alpha 1.01427
RAB6A RAB6A, member RAS oncogene family 0.989379
CXCL5 chemokine (C-X-C motif) ligand 5 0.983479
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 0.962891
WARS tryptophanyl-tRNA synthetase 0.962472
SFMBT1 Scm-like with four mbt domains 1 0.910199
DERA deoxyribose-phosphate aldolase (putative) 0.876557
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.812232
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.805257
GYG1 glycogenin 1 0.804436
ALLC allantoicase 0.800744
OVGP1 oviductal glycoprotein 1, 120kDa 0.800744
GPR148 G protein-coupled receptor 148 0.77575
DSTN destrin (actin depolymerizing factor) 0.770435
SIAE sialic acid acetylesterase 0.753306
RAB11A RAB11A, member RAS oncogene family 0.743141
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.731786
WASH7P WAS protein family homolog 7 pseudogene 0.725716
WASH1 WAS protein family homolog 1 0.721673
CPN1 carboxypeptidase N, polypeptide 1 0.719654
WASH6P WAS protein family homolog 6 pseudogene 0.71925
CEP104 centrosomal protein 104kDa 0.711183
OAZ1 ornithine decarboxylase antizyme 1 0.706351
TAS1R1 taste receptor, type 1, member 1 0.690694
MMP9 matrix metallopeptidase 9 0.673518
IL1B interleukin 1, beta 0.66914
RFX5 regulatory factor X, 5 (influences HLA class II expression) 0.66914
MMP12 matrix metallopeptidase 12 0.666358
MCHR1 melanin-concentrating hormone receptor 1 0.656046
GLS2 glutaminase 2 (liver, mitochondrial) 0.640645
IL13RA2 interleukin 13 receptor, alpha 2 0.61162
LYZ lysozyme 0.559062
WDFY2 WD repeat and FYVE domain containing 2 0.55712
HAS3 hyaluronan synthase 3 0.550134
PLCH2 phospholipase C, eta 2 0.533088
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 0.506507
HES2 hes family bHLH transcription factor 2 0.505356
OXT oxytocin/neurophysin I prepropeptide 0.498849
CTGF connective tissue growth factor 0.485505
TNF tumor necrosis factor 0.468819
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.463527
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.455978
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.443171
ANXA4 annexin A4 0.428891
IPP intracisternal A particle-promoted polypeptide 0.426265
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 0.406798
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.406798
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.406051
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.399334
TFG TRK-fused gene 0.392257
APOLD1 apolipoprotein L domain containing 1 0.378514
CXCL9 chemokine (C-X-C motif) ligand 9 0.369628
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.353395
MMP1 matrix metallopeptidase 1 0.341639
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.33651
IL1A interleukin 1, alpha 0.332121
PKN1 protein kinase N1 0.331756
ADD1 adducin 1 (alpha) 0.331025
NOS2 nitric oxide synthase 2, inducible 0.325187
NOD1 nucleotide-binding oligomerization domain containing 1 0.311377
FOSL1 FOS-like antigen 1 0.309928
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.30631
MMP7 matrix metallopeptidase 7 0.305948
PHB prohibitin 0.301615
ENG endoglin 0.290462
HLA-A major histocompatibility complex, class I, A 0.277584
FABP4 fatty acid binding protein 4, adipocyte 0.274732
CD4 CD4 molecule 0.274021
HSF4 heat shock transcription factor 4 0.269753
PER3 period circadian clock 3 0.26266
CENPV centromere protein V 0.25983
CCNE1 cyclin E1 0.246098
LPO lactoperoxidase 0.244345
TLR1 toll-like receptor 1 0.233878
TES testin LIM domain protein 0.223509
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.222479
GPANK1 G patch domain and ankyrin repeats 1 0.217352
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.215653
HLA-E major histocompatibility complex, class I, E 0.211934
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.211597
ANPEP alanyl (membrane) aminopeptidase 0.208579
HSPG2 heparan sulfate proteoglycan 2 0.192344
EPX eosinophil peroxidase 0.18651
CXCL10 chemokine (C-X-C motif) ligand 10 0.180937
CCL11 chemokine (C-C motif) ligand 11 0.177851
TLR2 toll-like receptor 2 0.174617
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.168381
LAMP1 lysosomal-associated membrane protein 1 0.167224
MGAM maltase-glucoamylase 0.166095
IRF6 interferon regulatory factor 6 0.159302
HSPA4 heat shock 70kDa protein 4 0.158266