trail Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

189 genes co-occuring with the biological term trail in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADAM17 ADAM metallopeptidase domain 17
AFP alpha-fetoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
BAD BCL2-associated agonist of cell death
BAG3 BCL2-associated athanogene 3
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCR breakpoint cluster region
BID BH3 interacting domain death agonist
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BNIPL BCL2/adenovirus E1B 19kD interacting protein like
BRCA1 breast cancer 1, early onset
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCDC26 CCDC26 long non-coding RNA
CCL8 chemokine (C-C motif) ligand 8
CCND3 cyclin D3
CD34 CD34 molecule
CD4 CD4 molecule
CDA cytidine deaminase
CDK15 cyclin-dependent kinase 15
CDK4 cyclin-dependent kinase 4
CFLAR CASP8 and FADD-like apoptosis regulator
CHEK2 checkpoint kinase 2
COMT catechol-O-methyltransferase
CREBBP CREB binding protein
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CYCS cytochrome c, somatic
CYLD cylindromatosis (turban tumor syndrome)
DDIT3 DNA-damage-inducible transcript 3
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DIABLO diablo, IAP-binding mitochondrial protein
EGR1 early growth response 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ERBB2 erb-b2 receptor tyrosine kinase 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGF2 fibroblast growth factor 2 (basic)
FOXO3 forkhead box O3
GMDS GDP-mannose 4,6-dehydratase
GSTP1 glutathione S-transferase pi 1
H2AFX H2A histone family, member X
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HOMER1 homer scaffolding protein 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSF1 heat shock transcription factor 1
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IFI6 interferon, alpha-inducible protein 6
IFN1@ interferon, type 1, cluster
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IFT57 intraflagellar transport 57
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL12A interleukin 12A
IL18 interleukin 18
IL21 interleukin 21
IL27 interleukin 27
IL3RA interleukin 3 receptor, alpha (low affinity)
IRF1 interferon regulatory factor 1
IRF7 interferon regulatory factor 7
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
JUN jun proto-oncogene
KIF2C kinesin family member 2C
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KPNB1 karyopherin (importin) beta 1
KRT8 keratin 8, type II
LGALS3 lectin, galactoside-binding, soluble, 3
MADD MAP-kinase activating death domain
MAGED2 melanoma antigen family D2
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MIR130A microRNA 130a
MIR137 microRNA 137
MIR182 microRNA 182
MIR221 microRNA 221
MIR222 microRNA 222
MIR34A microRNA 34a
MMP2 matrix metallopeptidase 2
MTDH metadherin
MUC16 mucin 16, cell surface associated
MVP major vault protein
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCAM1 neural cell adhesion molecule 1
NCOA3 nuclear receptor coactivator 3
NCOR2 nuclear receptor corepressor 2
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS1 nitric oxide synthase 1 (neuronal)
NT5E 5'-nucleotidase, ecto (CD73)
PACS2 phosphofurin acidic cluster sorting protein 2
PARP1 poly (ADP-ribose) polymerase 1
PAWR PRKC, apoptosis, WT1, regulator
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFB platelet-derived growth factor beta polypeptide
PEBP1 phosphatidylethanolamine binding protein 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAU plasminogen activator, urokinase
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRAME preferentially expressed antigen in melanoma
PRDX1 peroxiredoxin 1
PRDX4 peroxiredoxin 4
PRDX6 peroxiredoxin 6
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCQ protein kinase C, theta
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PUS10 pseudouridylate synthase 10
PVR poliovirus receptor
RBM5 RNA binding motif protein 5
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SOCS3 suppressor of cytokine signaling 3
SP1 Sp1 transcription factor
SPI1 Spi-1 proto-oncogene
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
TCF3 transcription factor 3
TERT telomerase reverse transcriptase
TF transferrin
TGFA transforming growth factor, alpha
TIMP3 TIMP metallopeptidase inhibitor 3
TLR3 toll-like receptor 3
TLR7 toll-like receptor 7
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TP53 tumor protein p53
UBE2C ubiquitin-conjugating enzyme E2C
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1
XAF1 XIAP associated factor 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YY1 YY1 transcription factor