tramp complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control. (Gene Ontology, GO_0031499)
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18 proteins co-occuring with the tramp complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ZCCHC7 zinc finger, CCHC domain containing 7 2.16759
PAPD7 PAP associated domain containing 7 1.67386
PAPD5 PAP associated domain containing 5 1.5017
NRD1 nardilysin (N-arginine dibasic convertase) 1.42993
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 1.39294
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 1.32005
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 1.17311
XRN2 5'-3' exoribonuclease 2 1.0934
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.969848
PRPF3 pre-mRNA processing factor 3 0.937377
ARNT aryl hydrocarbon receptor nuclear translocator 0.727047
PABPN1 poly(A) binding protein, nuclear 1 0.633732
NXF1 nuclear RNA export factor 1 0.594753
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.422389
AHR aryl hydrocarbon receptor 0.277038
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.235607
TOP1 topoisomerase (DNA) I 0.233459
RNASEH2A ribonuclease H2, subunit A 0.182122