| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the tranexamic acid-5762 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ABHD8 | abhydrolase domain containing 8 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| AHNAK | AHNAK nucleoprotein |
| APOC4 | apolipoprotein C-IV |
| ATP9A | ATPase, class II, type 9A |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2CD2L | C2CD2-like |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CA14 | carbonic anhydrase XIV |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CA9 | carbonic anhydrase IX |
| CCDC71 | coiled-coil domain containing 71 |
| CD34 | CD34 molecule |
| CD48 | CD48 molecule |
| CHI3L2 | chitinase 3-like 2 |
| CLCA1 | chloride channel accessory 1 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNTN6 | contactin 6 |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CRH | corticotropin releasing hormone |
| CRMP1 | collapsin response mediator protein 1 |
| CROCCP3 | ciliary rootlet coiled-coil, rootletin pseudogene 3 |
| CTSG | cathepsin G |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DENND2A | DENN/MADD domain containing 2A |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| EPS8L1 | EPS8-like 1 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| FAM65B | family with sequence similarity 65, member B |
| FAT4 | FAT atypical cadherin 4 |
| GPM6A | glycoprotein M6A |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GREM2 | gremlin 2, DAN family BMP antagonist |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GYG2 | glycogenin 2 |
| HAP1 | huntingtin-associated protein 1 |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HIST1H1D | histone cluster 1, H1d |
| HOXD11 | homeobox D11 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL36RN | interleukin 36 receptor antagonist |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KIAA1549L | KIAA1549-like |
| LAG3 | lymphocyte-activation gene 3 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| MEGF8 | multiple EGF-like-domains 8 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MLANA | melan-A |
| MPZ | myelin protein zero |
| MYEF2 | myelin expression factor 2 |
| NAGLU | N-acetylglucosaminidase, alpha |
| NKX3-1 | NK3 homeobox 1 |
| NRXN3 | neurexin 3 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| QPRT | quinolinate phosphoribosyltransferase |
| RRH | retinal pigment epithelium-derived rhodopsin homolog |
| RUNX2 | runt-related transcription factor 2 |
| SAFB | scaffold attachment factor B |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SEPP1 | selenoprotein P, plasma, 1 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMAD7 | SMAD family member 7 |
| SMC1A | structural maintenance of chromosomes 1A |
| SOCS3 | suppressor of cytokine signaling 3 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| T | T, brachyury homolog (mouse) |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TNS1 | tensin 1 |
| TNS4 | tensin 4 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 |
| TSC22D4 | TSC22 domain family, member 4 |
| TULP2 | tubby like protein 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WTAP | Wilms tumor 1 associated protein |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YIPF2 | Yip1 domain family, member 2 |
| ZCCHC11 | zinc finger, CCHC domain containing 11 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| AMT | aminomethyltransferase |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BMP15 | bone morphogenetic protein 15 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CES3 | carboxylesterase 3 |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLEC2B | C-type lectin domain family 2, member B |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CRLF1 | cytokine receptor-like factor 1 |
| DDN | dendrin |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| FGL1 | fibrinogen-like 1 |
| FOXN2 | forkhead box N2 |
| FUZ | fuzzy planar cell polarity protein |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GALK1 | galactokinase 1 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GRB7 | growth factor receptor-bound protein 7 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H4D | histone cluster 1, H4d |
| HOXA2 | homeobox A2 |
| HOXA7 | homeobox A7 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IFNA14 | interferon, alpha 14 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL12A | interleukin 12A |
| IL7 | interleukin 7 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRF6 | interferon regulatory factor 6 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT31 | keratin 31, type I |
| LIPG | lipase, endothelial |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MRAS | muscle RAS oncogene homolog |
| MXRA8 | matrix-remodelling associated 8 |
| MYH15 | myosin, heavy chain 15 |
| NAG18 | NAG18 mRNA |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OSMR | oncostatin M receptor |
| PER3 | period circadian clock 3 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRAMEF11 | PRAME family member 11 |
| PVRL3 | poliovirus receptor-related 3 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| S100A3 | S100 calcium binding protein A3 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SHPK | sedoheptulokinase |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIGD6 | tigger transposable element derived 6 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| UGT8 | UDP glycosyltransferase 8 |
| ZNF205 | zinc finger protein 205 |
| ZNF230 | zinc finger protein 230 |
| ZNF41 | zinc finger protein 41 |
| ZNF671 | zinc finger protein 671 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
