tranexamic-acid Gene Set
Genes
55 genes differentially expressed following the tranexamic-acid small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TATDN2
|
TatD DNase domain containing 2
|
4.73491
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
4.2715
|
|
HDHD3
|
haloacid dehalogenase-like hydrolase domain containing 3
|
4.14514
|
|
ATP2B2
|
ATPase, Ca++ transporting, plasma membrane 2
|
3.99041
|
|
PRPF4
|
pre-mRNA processing factor 4
|
3.74774
|
|
VTCN1
|
V-set domain containing T cell activation inhibitor 1
|
3.62692
|
|
DSCAM
|
Down syndrome cell adhesion molecule
|
3.49256
|
|
BSPRY
|
B-box and SPRY domain containing
|
3.47686
|
|
WDR45B
|
WD repeat domain 45B
|
3.46848
|
|
FSD1
|
fibronectin type III and SPRY domain containing 1
|
3.40912
|
|
MTMR1
|
myotubularin related protein 1
|
3.39732
|
|
SERPINA4
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
|
3.32982
|
|
ARHGEF9
|
Cdc42 guanine nucleotide exchange factor (GEF) 9
|
3.20798
|
|
UGT8
|
UDP glycosyltransferase 8
|
3.18
|
|
CUEDC1
|
CUE domain containing 1
|
3.15768
|
|
ITIH1
|
inter-alpha-trypsin inhibitor heavy chain 1
|
3.13678
|
|
TOR1B
|
torsin family 1, member B (torsin B)
|
3.12476
|
|
PLPPR1
|
phospholipid phosphatase related 1
|
3.06884
|
|
POLE3
|
polymerase (DNA directed), epsilon 3, accessory subunit
|
3.06436
|
|
GPR17
|
G protein-coupled receptor 17
|
3.05995
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
RPL6
|
ribosomal protein L6
|
-4.40736
|
|
HSPD1
|
heat shock 60kDa protein 1 (chaperonin)
|
-4.32807
|
|
GLI2
|
GLI family zinc finger 2
|
-4.08815
|
|
EPHB2
|
EPH receptor B2
|
-3.89111
|
|
CCDC181
|
coiled-coil domain containing 181
|
-3.69515
|
|
DNAI2
|
dynein, axonemal, intermediate chain 2
|
-3.62333
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-3.52335
|
|
ZNF480
|
zinc finger protein 480
|
-3.52331
|
|
BBS7
|
Bardet-Biedl syndrome 7
|
-3.41339
|
|
RPS25
|
ribosomal protein S25
|
-3.41101
|
|
TTTY15
|
testis-specific transcript, Y-linked 15 (non-protein coding)
|
-3.40815
|
|
FAT4
|
FAT atypical cadherin 4
|
-3.3004
|
|
CCDC33
|
coiled-coil domain containing 33
|
-3.28139
|
|
SPAG6
|
sperm associated antigen 6
|
-3.25619
|
|
OSGIN2
|
oxidative stress induced growth inhibitor family member 2
|
-3.25417
|
|
ZNF214
|
zinc finger protein 214
|
-3.23734
|
|
RPL4
|
ribosomal protein L4
|
-3.2146
|
|
RRAD
|
Ras-related associated with diabetes
|
-3.19539
|
|
USP9Y
|
ubiquitin specific peptidase 9, Y-linked
|
-3.17407
|
|
MTAP
|
methylthioadenosine phosphorylase
|
-3.16216
|
|
EIF1AY
|
eukaryotic translation initiation factor 1A, Y-linked
|
-3.15203
|
|
NLGN4Y
|
neuroligin 4, Y-linked
|
-3.14828
|
|
ME1
|
malic enzyme 1, NADP(+)-dependent, cytosolic
|
-3.12532
|
|
CNGB1
|
cyclic nucleotide gated channel beta 1
|
-3.10821
|
|
NACA
|
nascent polypeptide-associated complex alpha subunit
|
-3.1005
|
|
ADGB
|
androglobin
|
-3.09841
|
|
MTUS2
|
microtubule associated tumor suppressor candidate 2
|
-3.08928
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-3.07587
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-3.06628
|
|
RPS27A
|
ribosomal protein S27a
|
-3.06381
|
|
TBX1
|
T-box 1
|
-3.06291
|
|
ABHD6
|
abhydrolase domain containing 6
|
-3.04813
|
|
ATP2C2
|
ATPase, Ca++ transporting, type 2C, member 2
|
-3.04447
|
|
RPL11
|
ribosomal protein L11
|
-3.03372
|
|
TTLL5
|
tubulin tyrosine ligase-like family member 5
|
-3.02697
|
