transforming Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

371 genes co-occuring with the biological term transforming in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACVR1 activin A receptor, type I
ACVRL1 activin A receptor type II-like 1
ADAM17 ADAM metallopeptidase domain 17
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
AHI1 Abelson helper integration site 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAS2 5'-aminolevulinate synthase 2
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPTL4 angiopoietin-like 4
APOA1 apolipoprotein A-I
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARID1A AT rich interactive domain 1A (SWI-like)
ARRB2 arrestin, beta 2
ASPN asporin
BAG1 BCL2-associated athanogene
BAMBI BMP and activin membrane-bound inhibitor
BBC3 BCL2 binding component 3
BCAR1 breast cancer anti-estrogen resistance 1
BCAR4 breast cancer anti-estrogen resistance 4 (non-protein coding)
BCL2 B-cell CLL/lymphoma 2
BCR breakpoint cluster region
BGN biglycan
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSG basigin (Ok blood group)
BTK Bruton agammaglobulinemia tyrosine kinase
C5 complement component 5
C8ORF4 chromosome 8 open reading frame 4
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CD24 CD24 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CENPW centromere protein W
CKAP5 cytoskeleton associated protein 5
CLDN4 claudin 4
CNN1 calponin 1, basic, smooth muscle
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
CPD carboxypeptidase D
CREB1 cAMP responsive element binding protein 1
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSNK1D casein kinase 1, delta
CST3 cystatin C
CTCF CCCTC-binding factor (zinc finger protein)
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CUX1 cut-like homeobox 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAXX death-domain associated protein
DCN decorin
DEFA1 defensin, alpha 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDN1 endothelin 1
EED embryonic ectoderm development
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EHD1 EH-domain containing 1
EIF4E eukaryotic translation initiation factor 4E
ENG endoglin
EP300 E1A binding protein p300
ERAS ES cell expressed Ras
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERRFI1 ERBB receptor feedback inhibitor 1
ETV1 ets variant 1
EWSR1 EWS RNA-binding protein 1
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FAM134B family with sequence similarity 134, member B
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FBN1 fibrillin 1
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
FOXO3 forkhead box O3
FOXP1 forkhead box P1
FOXP3 forkhead box P3
FOXQ1 forkhead box Q1
FRS2 fibroblast growth factor receptor substrate 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GAEC1 gene amplified in esophageal cancer 1
GDF11 growth differentiation factor 11
GDF15 growth differentiation factor 15
GH1 growth hormone 1
GH2 growth hormone 2
GIPC1 GIPC PDZ domain containing family, member 1
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GOLM1 golgi membrane protein 1
GPC3 glypican 3
GPX1 glutathione peroxidase 1
GREM1 gremlin 1, DAN family BMP antagonist
GSK3B glycogen synthase kinase 3 beta
H2AFX H2A histone family, member X
HAS2 hyaluronan synthase 2
HAVCR2 hepatitis A virus cellular receptor 2
HDAC1 histone deacetylase 1
HDAC3 histone deacetylase 3
HEXIM1 hexamethylene bis-acetamide inducible 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
HNF4A hepatocyte nuclear factor 4, alpha
HOXA9 homeobox A9
HOXB9 homeobox B9
HRAS Harvey rat sarcoma viral oncogene homolog
HRH4 histamine receptor H4
HTRA2 HtrA serine peptidase 2
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL12A interleukin 12A
IL15 interleukin 15
IL17A interleukin 17A
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL2 interleukin 2
IL22 interleukin 22
IL27RA interleukin 27 receptor, alpha
IL2RA interleukin 2 receptor, alpha
IL6 interleukin 6
IL7 interleukin 7
INHA inhibin, alpha
INHBA inhibin, beta A
ITCH itchy E3 ubiquitin protein ligase
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
ITGB6 integrin, beta 6
ITGB8 integrin, beta 8
ITK IL2-inducible T-cell kinase
JAK3 Janus kinase 3
JUN jun proto-oncogene
KAT2B K(lysine) acetyltransferase 2B
KAT5 K(lysine) acetyltransferase 5
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KL klotho
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMA5 laminin, alpha 5
LBX1 ladybird homeobox 1
LDHA lactate dehydrogenase A
LEMD3 LEM domain containing 3
LEP leptin
LEPR leptin receptor
LOXL1 lysyl oxidase-like 1
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
LTBP3 latent transforming growth factor beta binding protein 3
LTBP4 latent transforming growth factor beta binding protein 4
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MECOM MDS1 and EVI1 complex locus
MED12 mediator complex subunit 12
MEN1 multiple endocrine neoplasia I
MERTK MER proto-oncogene, tyrosine kinase
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MIR106A microRNA 106a
MIR141 microRNA 141
MIR143 microRNA 143
MIR145 microRNA 145
MIR155 microRNA 155
MIR21 microRNA 21
MIR29A microRNA 29a
MIR365A microRNA 365a
MKI67 marker of proliferation Ki-67
MKL1 megakaryoblastic leukemia (translocation) 1
MKL2 MKL/myocardin-like 2
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MN1 meningioma (disrupted in balanced translocation) 1
MSN moesin
MTA1 metastasis associated 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYOCD myocardin
NANOG Nanog homeobox
NCOA3 nuclear receptor coactivator 3
NET1 neuroepithelial cell transforming 1
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFYA nuclear transcription factor Y, alpha
NKX2-1 NK2 homeobox 1
NODAL nodal growth differentiation factor
NOTCH1 notch 1
NOTCH3 notch 3
NOX1 NADPH oxidase 1
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR2C2 nuclear receptor subfamily 2, group C, member 2
NUP214 nucleoporin 214kDa
NUP98 nucleoporin 98kDa
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PARP1 poly (ADP-ribose) polymerase 1
PAX5 paired box 5
PCSK5 proprotein convertase subtilisin/kexin type 5
PDGFA platelet-derived growth factor alpha polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PELI2 pellino E3 ubiquitin protein ligase family member 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PML promyelocytic leukemia
POSTN periostin, osteoblast specific factor
POU5F1 POU class 5 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCD protein kinase C, delta
PRKCQ protein kinase C, theta
PROM1 prominin 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTK7 protein tyrosine kinase 7 (inactive)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTTG1 pituitary tumor-transforming 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RARA retinoic acid receptor, alpha
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RET ret proto-oncogene
RGL4 ral guanine nucleotide dissociation stimulator-like 4
RHOA ras homolog family member A
RNF11 ring finger protein 11
RNF111 ring finger protein 111
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNX2 runt-related transcription factor 2
SAP30L SAP30-like
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPA1 surfactant protein A1
SFTPC surfactant protein C
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHH sonic hedgehog
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD5 SMAD family member 5
SMAD7 SMAD family member 7
SMAD9 SMAD family member 9
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SOAT1 sterol O-acyltransferase 1
SOX4 SRY (sex determining region Y)-box 4
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPHK1 sphingosine kinase 1
SPHKAP SPHK1 interactor, AKAP domain containing
SPINK1 serine peptidase inhibitor, Kazal type 1
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11 serine/threonine kinase 11
SYK spleen tyrosine kinase
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TACC1 transforming, acidic coiled-coil containing protein 1
TACC3 transforming, acidic coiled-coil containing protein 3
TARDBP TAR DNA binding protein
TERT telomerase reverse transcriptase
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TGIF1 TGFB-induced factor homeobox 1
TGM2 transglutaminase 2
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TRADD TNFRSF1A-associated via death domain
TRIM29 tripartite motif containing 29
USP17L2 ubiquitin specific peptidase 17-like family member 2
VAV1 vav 1 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WISP2 WNT1 inducible signaling pathway protein 2
WWTR1 WW domain containing transcription regulator 1
YEATS4 YEATS domain containing 4
YIPF5 Yip1 domain family, member 5
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2
ZFP36 ZFP36 ring finger protein
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF580 zinc finger protein 580
ZYX zyxin