translocon complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins. (Gene Ontology, GO_0071256)
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Genes

153 proteins co-occuring with the translocon complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 2.49596
SEC63 SEC63 homolog (S. cerevisiae) 1.4559
SEC62 SEC62 homolog (S. cerevisiae) 1.3412
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 1.31789
SAMM50 SAMM50 sorting and assembly machinery component 1.30121
SRPR signal recognition particle receptor (docking protein) 1.17517
HSPA4 heat shock 70kDa protein 4 1.13727
DERL1 derlin 1 1.08272
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 1.0238
TRAM1 translocation associated membrane protein 1 0.929363
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 0.920449
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.90321
CANX calnexin 0.890245
SERP1 stress-associated endoplasmic reticulum protein 1 0.866746
RPN1 ribophorin I 0.863988
CHRDL1 chordin-like 1 0.859852
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 0.85388
DNAH8 dynein, axonemal, heavy chain 8 0.848369
TRAM2 translocation associated membrane protein 2 0.844696
LHFPL5 lipoma HMGIC fusion partner-like 5 0.827712
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 0.824959
SRP54 signal recognition particle 54kDa 0.8089
RPL23 ribosomal protein L23 0.732422
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.713682
ERP27 endoplasmic reticulum protein 27 0.711022
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 0.707482
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.664664
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.639717
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.601066
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 0.600223
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.596435
CKAP4 cytoskeleton-associated protein 4 0.588456
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 0.586361
DERL3 derlin 3 0.584268
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.578833
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 0.573411
ESX1 ESX homeobox 1 0.567169
FSD1 fibronectin type III and SPRY domain containing 1 0.567169
KRTCAP2 keratinocyte associated protein 2 0.566754
EXOC5 exocyst complex component 5 0.564677
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.562187
TSPAN16 tetraspanin 16 0.559285
HM13 histocompatibility (minor) 13 0.546885
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.545648
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.544411
DAD1 defender against cell death 1 0.541529
PEX14 peroxisomal biogenesis factor 14 0.527569
CALR calreticulin 0.523476
PRNP prion protein 0.523067
ASB14 ankyrin repeat and SOCS box containing 14 0.50107
TBX22 T-box 22 0.499042
LRMP lymphoid-restricted membrane protein 0.4958
EXOC6 exocyst complex component 6 0.475625
NRM nurim (nuclear envelope membrane protein) 0.475223
OPCML opioid binding protein/cell adhesion molecule-like 0.474018
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.463598
COX18 COX18 cytochrome c oxidase assembly factor 0.459203
BCAP31 B-cell receptor-associated protein 31 0.457208
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 0.451233
FAF2 Fas associated factor family member 2 0.44052
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 0.41221
SDPR serum deprivation response 0.405582
HIF3A hypoxia inducible factor 3, alpha subunit 0.398587
P4HB prolyl 4-hydroxylase, beta polypeptide 0.394323
NTM neurotrimin 0.392775
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.391228
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 0.387365
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.383895
YME1L1 YME1-like 1 ATPase 0.381969
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 0.374666
MIPEP mitochondrial intermediate peptidase 0.364331
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.357086
PRKCSH protein kinase C substrate 80K-H 0.355183
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.352901
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast) 0.351002
PEX12 peroxisomal biogenesis factor 12 0.351002
CHIA chitinase, acidic 0.347967
PEX10 peroxisomal biogenesis factor 10 0.337751
SRPRB signal recognition particle receptor, B subunit 0.329461
STATH statherin 0.329084
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.326829
ERO1L ERO1-like (S. cerevisiae) 0.318579
CRHR1 corticotropin releasing hormone receptor 1 0.310732
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 0.309613
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 0.30924
PEX13 peroxisomal biogenesis factor 13 0.308494
RPN2 ribophorin II 0.305143
EDNRB endothelin receptor type B 0.302168
CARD17 caspase recruitment domain family, member 17 0.29994
CABP1 calcium binding protein 1 0.294378
TRIM25 tripartite motif containing 25 0.293637
GFER growth factor, augmenter of liver regeneration 0.281821
CCDC130 coiled-coil domain containing 130 0.281453
HRC histidine rich calcium binding protein 0.279245
AACS acetoacetyl-CoA synthetase 0.278141
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 0.2708
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.268237
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 0.256561
TSPO translocator protein (18kDa) 0.253653
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 0.252202
REEP5 receptor accessory protein 5 0.24894
PRL prolactin 0.24894
GZMK granzyme K (granzyme 3; tryptase II) 0.245323
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 0.243519
ATOX1 antioxidant 1 copper chaperone 0.240276
PPID peptidylprolyl isomerase D 0.239197
FLAD1 flavin adenine dinucleotide synthetase 1 0.235249
KLK4 kallikrein-related peptidase 4 0.233817
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.227752
HLA-B major histocompatibility complex, class I, B 0.225976
SSH1 slingshot protein phosphatase 1 0.22385
MTTP microsomal triglyceride transfer protein 0.222083
PLXNA1 plexin A1 0.22173
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.220673
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.214017
AQP1 aquaporin 1 (Colton blood group) 0.209858
CLEC3B C-type lectin domain family 3, member B 0.208481
PEX2 peroxisomal biogenesis factor 2 0.201672
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.198658
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.197993
HSF4 heat shock transcription factor 4 0.195681
PEX6 peroxisomal biogenesis factor 6 0.193394
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.1921
METTL13 methyltransferase like 13 0.191777
SFTPA1 surfactant protein A1 0.188274
LAP3 leucine aminopeptidase 3 0.184853
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.183328
ERVW-1 endogenous retrovirus group W, member 1 0.182422
LOXL1 lysyl oxidase-like 1 0.180339
ASIC1 acid sensing (proton gated) ion channel 1 0.175188
PEX1 peroxisomal biogenesis factor 1 0.172201
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.165231
NLRC4 NLR family, CARD domain containing 4 0.162546
TRAC T cell receptor alpha constant 0.162117
ERF Ets2 repressor factor 0.161693
AQP4 aquaporin 4 0.159462
TXNDC9 thioredoxin domain containing 9 0.156863
MOGS mannosyl-oligosaccharide glucosidase 0.156688
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.156688
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 0.13974
XBP1 X-box binding protein 1 0.138852
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 0.138332
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 0.137843
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 0.137808
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 0.13779
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 0.137773
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 0.137773
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 0.137614
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.136317
UBE2K ubiquitin-conjugating enzyme E2K 0.136234
CLDN4 claudin 4 0.135938
UBE2S ubiquitin-conjugating enzyme E2S 0.135611
UBE2H ubiquitin-conjugating enzyme E2H 0.133006