transmembrane receptor protein serine/threonine kinase signaling pathway Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0007178)
External Link http://amigo.geneontology.org/amigo/term/GO_0007178
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Genes

131 genes participating in the transmembrane receptor protein serine/threonine kinase signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ACVR1 activin A receptor, type I
ACVR1B activin A receptor, type IB
ACVR1C activin A receptor, type IC
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
ACVRL1 activin A receptor type II-like 1
ADAM9 ADAM metallopeptidase domain 9
AMH anti-Mullerian hormone
AMHR2 anti-Mullerian hormone receptor, type II
APLP2 amyloid beta (A4) precursor-like protein 2
APOA1 apolipoprotein A-I
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARRB2 arrestin, beta 2
ATOH8 atonal homolog 8 (Drosophila)
BAMBI BMP and activin membrane-bound inhibitor
BMP10 bone morphogenetic protein 10
BMP15 bone morphogenetic protein 15
BMP2 bone morphogenetic protein 2
BMP3 bone morphogenetic protein 3
BMP4 bone morphogenetic protein 4
BMP5 bone morphogenetic protein 5
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BMP8A bone morphogenetic protein 8a
BMP8B bone morphogenetic protein 8b
BMPR1A bone morphogenetic protein receptor, type IA
BMPR1B bone morphogenetic protein receptor, type IB
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BTBD11 BTB (POZ) domain containing 11
CDH5 cadherin 5, type 2 (vascular endothelium)
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLDN5 claudin 5
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DLX5 distal-less homeobox 5
EID2 EP300 interacting inhibitor of differentiation 2
ENG endoglin
FAM83G family with sequence similarity 83, member G
FERMT2 fermitin family member 2
FKBP1A FK506 binding protein 1A, 12kDa
FNTA farnesyltransferase, CAAX box, alpha
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXH1 forkhead box H1
FSHB follicle stimulating hormone, beta polypeptide
FURIN furin (paired basic amino acid cleaving enzyme)
GARS1 glycyl-tRNA synthetase 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDF1 growth differentiation factor 1
GDF10 growth differentiation factor 10
GDF11 growth differentiation factor 11
GDF15 growth differentiation factor 15
GDF2 growth differentiation factor 2
GDF3 growth differentiation factor 3
GDF5 growth differentiation factor 5
GDF6 growth differentiation factor 6
GDF7 growth differentiation factor 7
GDF9 growth differentiation factor 9
GPI glucose-6-phosphate isomerase
HFE hemochromatosis
HFE2 hemochromatosis type 2 (juvenile)
HIPK2 homeodomain interacting protein kinase 2
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
INHA inhibin, alpha
INHBA inhibin, beta A
INHBB inhibin, beta B
INHBC inhibin, beta C
INHBE inhibin, beta E
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB5 integrin, beta 5
JUN jun proto-oncogene
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LPXN leupaxin
LRRC32 leucine rich repeat containing 32
LTBP2 latent transforming growth factor beta binding protein 2
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK3 mitogen-activated protein kinase 3
MEGF8 multiple EGF-like-domains 8
MSTN myostatin
NODAL nodal growth differentiation factor
NRROS negative regulator of reactive oxygen species
NUP93 nucleoporin 93kDa
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PPARG peroxisome proliferator-activated receptor gamma
PSG4 pregnancy specific beta-1-glycoprotein 4
PTK2 protein tyrosine kinase 2
PTPRK protein tyrosine phosphatase, receptor type, K
PXN paxillin
RGMA repulsive guidance molecule family member a
RGMB repulsive guidance molecule family member b
RNF111 ring finger protein 111
RUNX2 runt-related transcription factor 2
SCX scleraxis basic helix-loop-helix transcription factor
SIRT1 sirtuin 1
SKI SKI proto-oncogene
SLC39A5 solute carrier family 39 (zinc transporter), member 5
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD5 SMAD family member 5
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMAD9 SMAD family member 9
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM100 transmembrane protein 100
TWSG1 twisted gastrulation BMP signaling modulator 1
USP15 ubiquitin specific peptidase 15
USP9X ubiquitin specific peptidase 9, X-linked
USP9Y ubiquitin specific peptidase 9, Y-linked
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
ZFYVE9 zinc finger, FYVE domain containing 9
ZMIZ1 zinc finger, MIZ-type containing 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZYX zyxin