transmembrane receptor protein tyrosine kinase activity Gene Set

Dataset GO Molecular Function Annotations 2023
Category structural or functional annotations
Type biological process
Description Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. (Gene Ontology, GO_0004714)
External Link http://amigo.geneontology.org/amigo/term/GO:0004714
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Genes

51 genes performing the transmembrane receptor protein tyrosine kinase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

Symbol Name
ALK anaplastic lymphoma receptor tyrosine kinase
AXL AXL receptor tyrosine kinase
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CSF1R colony stimulating factor 1 receptor
DDR1 discoidin domain receptor tyrosine kinase 1
DDR2 discoidin domain receptor tyrosine kinase 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFR epidermal growth factor receptor
EPHA1 EPH receptor A1
EPHA2 EPH receptor A2
EPHA3 EPH receptor A3
EPHA5 EPH receptor A5
EPHB3 EPH receptor B3
EPHB4 EPH receptor B4
EPHB6 EPH receptor B6
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FGFRL1 fibroblast growth factor receptor-like 1
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
IGF1R insulin-like growth factor 1 receptor
IGF2R insulin-like growth factor 2 receptor
INSR insulin receptor
INSRR insulin receptor-related receptor
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LTK leukocyte receptor tyrosine kinase
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MST1R macrophage stimulating 1 receptor
MUSK muscle, skeletal, receptor tyrosine kinase
NELL1 NEL-like 1 (chicken)
NELL2 NEL-like 2 (chicken)
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
RET ret proto-oncogene
ROR1 receptor tyrosine kinase-like orphan receptor 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RYK receptor-like tyrosine kinase
TEK TEK tyrosine kinase, endothelial
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TYRO3 TYRO3 protein tyrosine kinase