transmembrane receptor protein tyrosine kinase adaptor activity Gene Set

Dataset	GO Molecular Function Annotations 2025
Category	structural or functional annotations
Type	molecular function
Description	The binding activity of a molecule that brings together a transmembrane receptor protein tyrosine kinase and one or more other molecules, permitting them to function in a coordinated way. (Gene Ontology, GO_0005068)
External Link	http://amigo.geneontology.org/amigo/term/GO:0005068
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Genes

14 genes performing the transmembrane receptor protein tyrosine kinase adaptor activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol	Name
BLNK	B-cell linker
FRS2	fibroblast growth factor receptor substrate 2
FRS3	fibroblast growth factor receptor substrate 3
GAB2	GRB2-associated binding protein 2
GAB4	GRB2-associated binding protein family, member 4
IRS1	insulin receptor substrate 1
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
SH2B1	SH2B adaptor protein 1
SH2B2	SH2B adaptor protein 2
SH2B3	SH2B adaptor protein 3
SHC1	SHC (Src homology 2 domain containing) transforming protein 1
STAP1	signal transducing adaptor family member 1
TRADD	TNFRSF1A-associated via death domain
TRAT1	T cell receptor associated transmembrane adaptor 1