A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0007185)
7 genes participating in the transmembrane receptor protein tyrosine phosphatase signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.