tranylcypromine-1417 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the tranylcypromine-1417 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIM1 absent in melanoma 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANXA2 annexin A2
ANXA2P2 annexin A2 pseudogene 2
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ATXN2 ataxin 2
BAHCC1 BAH domain and coiled-coil containing 1
BCL3 B-cell CLL/lymphoma 3
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CAPN2 calpain 2, (m/II) large subunit
CAST calpastatin
CD84 CD84 molecule
CHKB choline kinase beta
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCAF15 DDB1 and CUL4 associated factor 15
DLX2 distal-less homeobox 2
DMBT1 deleted in malignant brain tumors 1
DSCR3 Down syndrome critical region 3
DUS2 dihydrouridine synthase 2
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EMILIN2 elastin microfibril interfacer 2
EML2 echinoderm microtubule associated protein like 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM102A family with sequence similarity 102, member A
FAM134B family with sequence similarity 134, member B
FBXL18 F-box and leucine-rich repeat protein 18
FBXO21 F-box protein 21
FBXO42 F-box protein 42
FLJ42627 uncharacterized LOC645644
FNBP1 formin binding protein 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLIPR1 GLI pathogenesis-related 1
GPR65 G protein-coupled receptor 65
GRK6 G protein-coupled receptor kinase 6
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTT huntingtin
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFI16 interferon, gamma-inducible protein 16
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL1RN interleukin 1 receptor antagonist
ITGB1BP1 integrin beta 1 binding protein 1
KCTD12 potassium channel tetramerization domain containing 12
KIAA0226 KIAA0226
KLF4 Kruppel-like factor 4 (gut)
LRRK1 leucine-rich repeat kinase 1
LY96 lymphocyte antigen 96
MAST2 microtubule associated serine/threonine kinase 2
MLH3 mutL homolog 3
MPZL1 myelin protein zero-like 1
MYOF myoferlin
NEBL nebulette
OCRL oculocerebrorenal syndrome of Lowe
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OGFRL1 opioid growth factor receptor-like 1
OSBPL11 oxysterol binding protein-like 11
PFKM phosphofructokinase, muscle
PIAS4 protein inhibitor of activated STAT, 4
PLD2 phospholipase D2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLIN2 perilipin 2
PPAP2A phosphatidic acid phosphatase type 2A
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PTMA prothymosin, alpha
RBM47 RNA binding motif protein 47
RNASE6 ribonuclease, RNase A family, k6
RPL10 ribosomal protein L10
S1PR4 sphingosine-1-phosphate receptor 4
SCPEP1 serine carboxypeptidase 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMAD3 SMAD family member 3
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNORA21 small nucleolar RNA, H/ACA box 21
SP140L SP140 nuclear body protein-like
SPEF1 sperm flagellar 1
STAT4 signal transducer and activator of transcription 4
SURF2 surfeit 2
TFR2 transferrin receptor 2
TIGAR TP53 induced glycolysis regulatory phosphatase
TMEM243 transmembrane protein 243, mitochondrial
TMPRSS6 transmembrane protease, serine 6
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TRIB2 tribbles pseudokinase 2
TRIM68 tripartite motif containing 68
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSSC4 tumor suppressing subtransferable candidate 4
USP20 ubiquitin specific peptidase 20
VCAN versican
WDR44 WD repeat domain 44
ZC2HC1A zinc finger, C2HC-type containing 1A
ZC4H2 zinc finger, C4H2 domain containing
ZER1 zyg-11 related, cell cycle regulator
ZNF426 zinc finger protein 426
ZNF451 zinc finger protein 451

decreased expression

Symbol Name
ALPK1 alpha-kinase 1
ASB8 ankyrin repeat and SOCS box containing 8
ATF3 activating transcription factor 3
AZI2 5-azacytidine induced 2
BCORL1 BCL6 corepressor-like 1
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CD1A CD1a molecule
CD38 CD38 molecule
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
CDK6 cyclin-dependent kinase 6
CDK8 cyclin-dependent kinase 8
CETN1 centrin, EF-hand protein, 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN15 claudin 15
DIABLO diablo, IAP-binding mitochondrial protein
DTX4 deltex 4, E3 ubiquitin ligase
DUSP2 dual specificity phosphatase 2
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EDAR ectodysplasin A receptor
ELOVL6 ELOVL fatty acid elongase 6
FADS2 fatty acid desaturase 2
FAM57A family with sequence similarity 57, member A
FUBP3 far upstream element (FUSE) binding protein 3
GJD2 gap junction protein, delta 2, 36kDa
GRM4 glutamate receptor, metabotropic 4
GSR glutathione reductase
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HMGB3P1 high mobility group box 3 pseudogene 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFT20 intraflagellar transport 20
ITPKC inositol-trisphosphate 3-kinase C
KIFC1 kinesin family member C1
LIAS lipoic acid synthetase
LMNB1 lamin B1
MAGOHB mago-nashi homolog B (Drosophila)
MAGT1 magnesium transporter 1
MICA MHC class I polypeptide-related sequence A
MOB3B MOB kinase activator 3B
MORC3 MORC family CW-type zinc finger 3
MRGBP MRG/MORF4L binding protein
MT1HL1 metallothionein 1H-like 1
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NFE2L2 nuclear factor, erythroid 2-like 2
NMD3 NMD3 ribosome export adaptor
NOL6 nucleolar protein 6 (RNA-associated)
NUBP2 nucleotide binding protein 2
NUBPL nucleotide binding protein-like
NXPH3 neurexophilin 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PCSK7 proprotein convertase subtilisin/kexin type 7
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POMT1 protein-O-mannosyltransferase 1
PRPF39 pre-mRNA processing factor 39
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSAT1 phosphoserine aminotransferase 1
PTER phosphotriesterase related
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGES2 prostaglandin E synthase 2
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RECQL4 RecQ protein-like 4
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF144A ring finger protein 144A
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPS14P3 ribosomal protein S14 pseudogene 3
S100P S100 calcium binding protein P
SDHAF3 succinate dehydrogenase complex assembly factor 3
SIPA1 signal-induced proliferation-associated 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC25A40 solute carrier family 25, member 40
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SMC2 structural maintenance of chromosomes 2
SPIN1 spindlin 1
SPON2 spondin 2, extracellular matrix protein
SSBP3 single stranded DNA binding protein 3
SSFA2 sperm specific antigen 2
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TET3 tet methylcytosine dioxygenase 3
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
TMEM38B transmembrane protein 38B
TOM1L1 target of myb1 (chicken)-like 1
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
TWIST1 twist family bHLH transcription factor 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
WRN Werner syndrome, RecQ helicase-like
XAF1 XIAP associated factor 1
YAF2 YY1 associated factor 2
ZBED1 zinc finger, BED-type containing 1
ZBTB39 zinc finger and BTB domain containing 39
ZEB2 zinc finger E-box binding homeobox 2
ZNF140 zinc finger protein 140
ZNF23 zinc finger protein 23
ZNF250 zinc finger protein 250
ZNF264 zinc finger protein 264
ZNHIT2 zinc finger, HIT-type containing 2
ZNRD1-AS1 ZNRD1 antisense RNA 1