tranylcypromine-2101 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the tranylcypromine-2101 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTSL3 ADAMTS-like 3
ADGRE2 adhesion G protein-coupled receptor E2
ADRBK1 adrenergic, beta, receptor kinase 1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALPK3 alpha-kinase 3
APC adenomatous polyposis coli
ARHGAP26 Rho GTPase activating protein 26
ARMC4 armadillo repeat containing 4
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATXN7L3B ataxin 7-like 3B
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCR breakpoint cluster region
BTF3P11 basic transcription factor 3 pseudogene 11
C17ORF80 chromosome 17 open reading frame 80
C1ORF54 chromosome 1 open reading frame 54
CCDC88A coiled-coil domain containing 88A
CGA glycoprotein hormones, alpha polypeptide
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COBL cordon-bleu WH2 repeat protein
CORO2B coronin, actin binding protein, 2B
CSF1R colony stimulating factor 1 receptor
CYLD cylindromatosis (turban tumor syndrome)
DEPDC5 DEP domain containing 5
DGKE diacylglycerol kinase, epsilon 64kDa
ENG endoglin
ERC1 ELKS/RAB6-interacting/CAST family member 1
FAS Fas cell surface death receptor
FGF1 fibroblast growth factor 1 (acidic)
FLJ22184
GOLGA2 golgin A2
HIST1H2AJ histone cluster 1, H2aj
HOXB5 homeobox B5
ING1 inhibitor of growth family, member 1
IQCE IQ motif containing E
JUN jun proto-oncogene
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD14 potassium channel tetramerization domain containing 14
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KRT86 keratin 86, type II
LAT2 linker for activation of T cells family, member 2
LEFTY2 left-right determination factor 2
LINC00341 long intergenic non-protein coding RNA 341
LRRC40 leucine rich repeat containing 40
LRRK1 leucine-rich repeat kinase 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD3 LY6/PLAUR domain containing 3
MAGOH2P mago-nashi homolog 2, pseudogene
MKL1 megakaryoblastic leukemia (translocation) 1
MRPL41 mitochondrial ribosomal protein L41
MSL3 male-specific lethal 3 homolog (Drosophila)
MTUS1 microtubule associated tumor suppressor 1
MUC3B mucin 3B, cell surface associated
MYOZ3 myozenin 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NEBL nebulette
NF2 neurofibromin 2 (merlin)
NOL12 nucleolar protein 12
NPR1 natriuretic peptide receptor 1
NTF3 neurotrophin 3
NUP160 nucleoporin 160kDa
OVOL2 ovo-like zinc finger 2
PARVA parvin, alpha
PCDHGA10 protocadherin gamma subfamily A, 10
PCLO piccolo presynaptic cytomatrix protein
PDGFB platelet-derived growth factor beta polypeptide
PDLIM7 PDZ and LIM domain 7 (enigma)
PEX11A peroxisomal biogenesis factor 11 alpha
PLCH1 phospholipase C, eta 1
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRPF18 pre-mRNA processing factor 18
PTGFR prostaglandin F receptor (FP)
RNF2 ring finger protein 2
RNFT2 ring finger protein, transmembrane 2
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SETD2 SET domain containing 2
SH3BP2 SH3-domain binding protein 2
SIKE1 suppressor of IKBKE 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLITRK5 SLIT and NTRK-like family, member 5
SND1-IT1 SND1 intronic transcript 1
SOCS6 suppressor of cytokine signaling 6
SPRR1A small proline-rich protein 1A
STK17A serine/threonine kinase 17a
SUGCT succinyl-CoA:glutarate-CoA transferase
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBD thrombomodulin
TMEM57 transmembrane protein 57
TMEM63A transmembrane protein 63A
VASH1 vasohibin 1
ZBTB22 zinc finger and BTB domain containing 22
ZBTB43 zinc finger and BTB domain containing 43
ZNF287 zinc finger protein 287
ZNF385D zinc finger protein 385D
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM15 ADAM metallopeptidase domain 15
AEN apoptosis enhancing nuclease
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AMDHD2 amidohydrolase domain containing 2
ANXA2P3 annexin A2 pseudogene 3
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ATP7B ATPase, Cu++ transporting, beta polypeptide
BNC1 basonuclin 1
C16ORF62 chromosome 16 open reading frame 62
C1ORF105 chromosome 1 open reading frame 105
CCDC85C coiled-coil domain containing 85C
CDK3 cyclin-dependent kinase 3
CHMP6 charged multivesicular body protein 6
CLCN5 chloride channel, voltage-sensitive 5
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
DEAF1 DEAF1 transcription factor
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DTWD1 DTW domain containing 1
EGLN2 egl-9 family hypoxia-inducible factor 2
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FANCC Fanconi anemia, complementation group C
FBXL15 F-box and leucine-rich repeat protein 15
FLCN folliculin
FOXJ2 forkhead box J2
GDAP2 ganglioside induced differentiation associated protein 2
GID4 GID complex subunit 4
GMIP GEM interacting protein
HIRA histone cell cycle regulator
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HMGB3P1 high mobility group box 3 pseudogene 1
HSF2BP heat shock transcription factor 2 binding protein
INPP5K inositol polyphosphate-5-phosphatase K
INPPL1 inositol polyphosphate phosphatase-like 1
IQCG IQ motif containing G
IREB2 iron-responsive element binding protein 2
JAM3 junctional adhesion molecule 3
JUNB jun B proto-oncogene
KDM5C lysine (K)-specific demethylase 5C
KIAA0513 KIAA0513
KRI1 KRI1 homolog (S. cerevisiae)
LIAS lipoic acid synthetase
LOC100127972 uncharacterized LOC100127972
MACROD1 MACRO domain containing 1
MAMLD1 mastermind-like domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MICALL2 MICAL-like 2
MTERF1 mitochondrial transcription termination factor 1
MXD3 MAX dimerization protein 3
MYNN myoneurin
NDRG4 NDRG family member 4
NID2 nidogen 2 (osteonidogen)
NOD1 nucleotide-binding oligomerization domain containing 1
OCEL1 occludin/ELL domain containing 1
OSMR oncostatin M receptor
PBLD phenazine biosynthesis-like protein domain containing
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PRAME preferentially expressed antigen in melanoma
PRKX protein kinase, X-linked
PTGES2 prostaglandin E synthase 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RIN1 Ras and Rab interactor 1
RNF31 ring finger protein 31
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPEG SPEG complex locus
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
SYNPO synaptopodin
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TNRC6B trinucleotide repeat containing 6B
TNS2 tensin 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSKU tsukushi, small leucine rich proteoglycan
TSPAN8 tetraspanin 8
TWF2 twinfilin actin binding protein 2
TWISTNB TWIST neighbor
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF107 zinc finger protein 107
ZNF250 zinc finger protein 250
ZNF254 zinc finger protein 254
ZNF34 zinc finger protein 34
ZSCAN26 zinc finger and SCAN domain containing 26