tranylcypromine-5996 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tranylcypromine-5996 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRA2 adhesion G protein-coupled receptor A2
AEBP1 AE binding protein 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
CEP162 centrosomal protein 162kDa
CFAP70 cilia and flagella associated protein 70
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLGN calmegin
COL11A2 collagen, type XI, alpha 2
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAGLA diacylglycerol lipase, alpha
DIEXF digestive organ expansion factor homolog (zebrafish)
DIO2 deiodinase, iodothyronine, type II
DKFZP434L187 uncharacterized LOC26082
DMPK dystrophia myotonica-protein kinase
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOCK6 dedicator of cytokinesis 6
DUOX1 dual oxidase 1
DUSP9 dual specificity phosphatase 9
ELOVL2 ELOVL fatty acid elongase 2
FADS3 fatty acid desaturase 3
FBXL7 F-box and leucine-rich repeat protein 7
FGFR1 fibroblast growth factor receptor 1
FGL2 fibrinogen-like 2
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FSCN1 fascin actin-bundling protein 1
FST follistatin
GGT1 gamma-glutamyltransferase 1
GJA4 gap junction protein, alpha 4, 37kDa
GJB3 gap junction protein, beta 3, 31kDa
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GP1BB glycoprotein Ib (platelet), beta polypeptide
GPR107 G protein-coupled receptor 107
GRM2 glutamate receptor, metabotropic 2
GRM6 glutamate receptor, metabotropic 6
GYPB glycophorin B (MNS blood group)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HDAC6 histone deacetylase 6
HLA-J major histocompatibility complex, class I, J (pseudogene)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF5 interferon regulatory factor 5
JAG1 jagged 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LIME1 Lck interacting transmembrane adaptor 1
LINC00260 long intergenic non-protein coding RNA 260
MMP25 matrix metallopeptidase 25
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NNAT neuronatin
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSBPL10 oxysterol binding protein-like 10
OVOL2 ovo-like zinc finger 2
PADI1 peptidyl arginine deiminase, type I
PEAK1 pseudopodium-enriched atypical kinase 1
PGAP1 post-GPI attachment to proteins 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKNOX2 PBX/knotted 1 homeobox 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNA2 plexin A2
PODNL1 podocan-like 1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PQLC2 PQ loop repeat containing 2
PTPRM protein tyrosine phosphatase, receptor type, M
QPCT glutaminyl-peptide cyclotransferase
R3HDM1 R3H domain containing 1
RAB33A RAB33A, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RFTN1 raftlin, lipid raft linker 1
RPL35A ribosomal protein L35a
S100A8 S100 calcium binding protein A8
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SIGLEC6 sialic acid binding Ig-like lectin 6
SIGLEC7 sialic acid binding Ig-like lectin 7
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNED1 sushi, nidogen and EGF-like domains 1
STK11 serine/threonine kinase 11
TAL1 T-cell acute lymphocytic leukemia 1
TDRD12 tudor domain containing 12
THY1 Thy-1 cell surface antigen
TMEM53 transmembrane protein 53
TRD T cell receptor delta locus
TRIM3 tripartite motif containing 3
WNT5A wingless-type MMTV integration site family, member 5A
ZEB1 zinc finger E-box binding homeobox 1
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF280A zinc finger protein 280A

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
APLP1 amyloid beta (A4) precursor-like protein 1
ATG2A autophagy related 2A
ATG9A autophagy related 9A
B9D2 B9 protein domain 2
C19ORF40 chromosome 19 open reading frame 40
C4ORF29 chromosome 4 open reading frame 29
CALCOCO1 calcium binding and coiled-coil domain 1
CCNO cyclin O
CDON cell adhesion associated, oncogene regulated
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRM3 cholinergic receptor, muscarinic 3
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN15 claudin 15
CORT cortistatin
CSF1R colony stimulating factor 1 receptor
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DNMBP dynamin binding protein
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DRD1 dopamine receptor D1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FAN1 FANCD2/FANCI-associated nuclease 1
FBXL6 F-box and leucine-rich repeat protein 6
FGF23 fibroblast growth factor 23
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GID4 GID complex subunit 4
GPATCH3 G patch domain containing 3
HELZ helicase with zinc finger
HIST1H4D histone cluster 1, H4d
IFT22 intraflagellar transport 22
IL17RA interleukin 17 receptor A
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0125 KIAA0125
KIAA0319L KIAA0319-like
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LOC100272216 uncharacterized LOC100272216
MAGEF1 melanoma antigen family F1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MBNL3 muscleblind-like splicing regulator 3
MYL5 myosin, light chain 5, regulatory
NAG18 NAG18 mRNA
NPFFR1 neuropeptide FF receptor 1
OGFRL1 opioid growth factor receptor-like 1
ONECUT2 one cut homeobox 2
OSMR oncostatin M receptor
PCDHA6 protocadherin alpha 6
PCDHB3 protocadherin beta 3
PDE12 phosphodiesterase 12
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PITX2 paired-like homeodomain 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PMCH pro-melanin-concentrating hormone
POMT2 protein-O-mannosyltransferase 2
PQLC1 PQ loop repeat containing 1
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTPRG protein tyrosine phosphatase, receptor type, G
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RUFY2 RUN and FYVE domain containing 2
SAMD9 sterile alpha motif domain containing 9
SCN1B sodium channel, voltage gated, type I beta subunit
SETD1A SET domain containing 1A
SGK1 serum/glucocorticoid regulated kinase 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC35F5 solute carrier family 35, member F5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNX16 sorting nexin 16
STAG3 stromal antigen 3
TBX19 T-box 19
THBS3 thrombospondin 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TRAF2 TNF receptor-associated factor 2
TRAPPC13 trafficking protein particle complex 13
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP19 ubiquitin specific peptidase 19
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBED1 zinc finger, BED-type containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZBTB48 zinc finger and BTB domain containing 48
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF107 zinc finger protein 107
ZNF212 zinc finger protein 212
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF324 zinc finger protein 324
ZNF329 zinc finger protein 329
ZNF510 zinc finger protein 510
ZNF747 zinc finger protein 747
ZNF768 zinc finger protein 768
ZNF770 zinc finger protein 770