trapidil-3136 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the trapidil-3136 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
ANGPTL2 angiopoietin-like 2
ANKH ANKH inorganic pyrophosphate transport regulator
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
BCAS3 breast carcinoma amplified sequence 3
BMP1 bone morphogenetic protein 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1ORF68 chromosome 1 open reading frame 68
CA5B carbonic anhydrase VB, mitochondrial
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD79B CD79b molecule, immunoglobulin-associated beta
COL10A1 collagen, type X, alpha 1
CRELD1 cysteine-rich with EGF-like domains 1
CRY2 cryptochrome circadian clock 2
CTSZ cathepsin Z
CXCR3 chemokine (C-X-C motif) receptor 3
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DGAT1 diacylglycerol O-acyltransferase 1
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DSTYK dual serine/threonine and tyrosine protein kinase
EFNA3 ephrin-A3
ENDOD1 endonuclease domain containing 1
EPHB4 EPH receptor B4
EZR ezrin
F5 coagulation factor V (proaccelerin, labile factor)
FAM155A family with sequence similarity 155, member A
FAM46C family with sequence similarity 46, member C
FAS Fas cell surface death receptor
FN1 fibronectin 1
FOXG1 forkhead box G1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAS6 growth arrest-specific 6
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GLP1R glucagon-like peptide 1 receptor
GPM6A glycoprotein M6A
HOXA9 homeobox A9
HSPA2 heat shock 70kDa protein 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HYAL1 hyaluronoglucosaminidase 1
ICA1 islet cell autoantigen 1, 69kDa
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCTD13 potassium channel tetramerization domain containing 13
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LRRC23 leucine rich repeat containing 23
LRRC49 leucine rich repeat containing 49
MID1 midline 1
MIR600HG MIR600 host gene
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MXD4 MAX dimerization protein 4
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NR2F2 nuclear receptor subfamily 2, group F, member 2
OLFML2A olfactomedin-like 2A
OR3A3 olfactory receptor, family 3, subfamily A, member 3
ORAI2 ORAI calcium release-activated calcium modulator 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDCD6 programmed cell death 6
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PER1 period circadian clock 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PPARD peroxisome proliferator-activated receptor delta
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKCE protein kinase C, epsilon
PRPH peripherin
PRSS53 protease, serine, 53
RBM17 RNA binding motif protein 17
RIMS1 regulating synaptic membrane exocytosis 1
RPL10L ribosomal protein L10-like
RYR2 ryanodine receptor 2 (cardiac)
S100A2 S100 calcium binding protein A2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SPATA2L spermatogenesis associated 2-like
SRR serine racemase
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYT5 synaptotagmin V
T T, brachyury homolog (mouse)
TBXA2R thromboxane A2 receptor
TICAM1 toll-like receptor adaptor molecule 1
TJAP1 tight junction associated protein 1 (peripheral)
TLDC1 TBC/LysM-associated domain containing 1
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TTC27 tetratricopeptide repeat domain 27
UNC93B1 unc-93 homolog B1 (C. elegans)
WTAP Wilms tumor 1 associated protein
YLPM1 YLP motif containing 1
YPEL1 yippee-like 1 (Drosophila)
ZC3H7B zinc finger CCCH-type containing 7B
ZNF428 zinc finger protein 428
ZNF696 zinc finger protein 696
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
AHDC1 AT hook, DNA binding motif, containing 1
ALDH8A1 aldehyde dehydrogenase 8 family, member A1
APOBR apolipoprotein B receptor
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ATG10 autophagy related 10
BEND5 BEN domain containing 5
BEST1 bestrophin 1
C17ORF70 chromosome 17 open reading frame 70
C1QTNF3 C1q and tumor necrosis factor related protein 3
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPN5 calpain 5
CBR3 carbonyl reductase 3
CCDC176 coiled-coil domain containing 176
CDCP1 CUB domain containing protein 1
CDHR2 cadherin-related family member 2
CDR2L cerebellar degeneration-related protein 2-like
CHPF chondroitin polymerizing factor
CLEC2D C-type lectin domain family 2, member D
CNTN1 contactin 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CROT carnitine O-octanoyltransferase
CTSV cathepsin V
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EXD3 exonuclease 3'-5' domain containing 3
EXOSC1 exosome component 1
FGF9 fibroblast growth factor 9
FLCN folliculin
FLJ21369 uncharacterized protein FLJ21369
FLT4 fms-related tyrosine kinase 4
GAA glucosidase, alpha; acid
GEM GTP binding protein overexpressed in skeletal muscle
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPR3 G protein-coupled receptor 3
HIST1H1T histone cluster 1, H1t
HIST1H2AI histone cluster 1, H2ai
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMB major histocompatibility complex, class II, DM beta
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IDI2-AS1 IDI2 antisense RNA 1
IFT81 intraflagellar transport 81
IL12B interleukin 12B
IL2 interleukin 2
IQSEC2 IQ motif and Sec7 domain 2
IRF1 interferon regulatory factor 1
LIMD2 LIM domain containing 2
LRP2 low density lipoprotein receptor-related protein 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MCPH1 microcephalin 1
MKL2 MKL/myocardin-like 2
MKRN3 makorin ring finger protein 3
MPZ myelin protein zero
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NAG18 NAG18 mRNA
ODF2 outer dense fiber of sperm tails 2
PADI1 peptidyl arginine deiminase, type I
PDE8B phosphodiesterase 8B
PDGFRL platelet-derived growth factor receptor-like
PKD2L2 polycystic kidney disease 2-like 2
POLH polymerase (DNA directed), eta
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP1R13B protein phosphatase 1, regulatory subunit 13B
RAB13 RAB13, member RAS oncogene family
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RND1 Rho family GTPase 1
RNF126P1 ring finger protein 126 pseudogene 1
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SHARPIN SHANK-associated RH domain interactor
SIRT6 sirtuin 6
SLC22A18 solute carrier family 22, member 18
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMR3A submaxillary gland androgen regulated protein 3A
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
TAS2R10 taste receptor, type 2, member 10
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMC5 transmembrane channel-like 5
TMEM120B transmembrane protein 120B
TMEM209 transmembrane protein 209
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TWSG1 twisted gastrulation BMP signaling modulator 1
UBTD1 ubiquitin domain containing 1
USP18 ubiquitin specific peptidase 18
ZFHX3 zinc finger homeobox 3
ZFYVE9 zinc finger, FYVE domain containing 9
ZIM2 zinc finger, imprinted 2
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF41 zinc finger protein 41
ZNF528 zinc finger protein 528
ZNF85 zinc finger protein 85
ZNF93 zinc finger protein 93