trapidil-6515 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the trapidil-6515 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK2 aarF domain containing kinase 2
AGMAT agmatine ureohydrolase (agmatinase)
AK2 adenylate kinase 2
AKAP7 A kinase (PRKA) anchor protein 7
ALS2CL ALS2 C-terminal like
AQP3 aquaporin 3 (Gill blood group)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ATG3 autophagy related 3
C19ORF73 chromosome 19 open reading frame 73
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CALD1 caldesmon 1
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CCDC71 coiled-coil domain containing 71
CCRL2 chemokine (C-C motif) receptor-like 2
CD6 CD6 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CEP164 centrosomal protein 164kDa
CLTA clathrin, light chain A
CNOT4 CCR4-NOT transcription complex, subunit 4
CSPP1 centrosome and spindle pole associated protein 1
DCAF11 DDB1 and CUL4 associated factor 11
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EFNB3 ephrin-B3
FBXO4 F-box protein 4
FGF13 fibroblast growth factor 13
GAP43 growth associated protein 43
GLUL glutamate-ammonia ligase
GMPR guanosine monophosphate reductase
GREB1 growth regulation by estrogen in breast cancer 1
GRIK2 glutamate receptor, ionotropic, kainate 2
ICOS inducible T-cell co-stimulator
IL11 interleukin 11
INCENP inner centromere protein antigens 135/155kDa
IRGC immunity-related GTPase family, cinema
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAM3 junctional adhesion molecule 3
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL22 kelch-like family member 22
KRIT1 KRIT1, ankyrin repeat containing
LARP7 La ribonucleoprotein domain family, member 7
LGALS2 lectin, galactoside-binding, soluble, 2
LIN7A lin-7 homolog A (C. elegans)
LMF2 lipase maturation factor 2
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAOB monoamine oxidase B
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK11 mitogen-activated protein kinase 11
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCM3AP minichromosome maintenance complex component 3 associated protein
MIP major intrinsic protein of lens fiber
MKL1 megakaryoblastic leukemia (translocation) 1
MSI1 musashi RNA-binding protein 1
MST1L macrophage stimulating 1-like
MX1 MX dynamin-like GTPase 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PDLIM7 PDZ and LIM domain 7 (enigma)
PER1 period circadian clock 1
PLAUR plasminogen activator, urokinase receptor
PLCL2 phospholipase C-like 2
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTEL1 regulator of telomere elongation helicase 1
SCARB1 scavenger receptor class B, member 1
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SH3BP2 SH3-domain binding protein 2
SIPA1 signal-induced proliferation-associated 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLMO1 slowmo homolog 1 (Drosophila)
SPO11 SPO11 meiotic protein covalently bound to DSB
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAS2R1 taste receptor, type 2, member 1
TCP11L1 t-complex 11, testis-specific-like 1
TFEB transcription factor EB
THAP3 THAP domain containing, apoptosis associated protein 3
TLE4 transducin-like enhancer of split 4
TMPRSS2 transmembrane protease, serine 2
TOX4 TOX high mobility group box family member 4
TRIL TLR4 interactor with leucine-rich repeats
TRIM66 tripartite motif containing 66
TSC22D2 TSC22 domain family, member 2
TUBA3C tubulin, alpha 3c
USP46 ubiquitin specific peptidase 46
VCAN versican
WDR62 WD repeat domain 62
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZNF280A zinc finger protein 280A
ZNF749 zinc finger protein 749

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
AMH anti-Mullerian hormone
ANXA2P3 annexin A2 pseudogene 3
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
BCAS1 breast carcinoma amplified sequence 1
BTBD2 BTB (POZ) domain containing 2
C17ORF80 chromosome 17 open reading frame 80
C8ORF60 chromosome 8 open reading frame 60
CCDC9 coiled-coil domain containing 9
CDKN2AIP CDKN2A interacting protein
CEP97 centrosomal protein 97kDa
CFAP44 cilia and flagella associated protein 44
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
DDIT3 DNA-damage-inducible transcript 3
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DNAH17 dynein, axonemal, heavy chain 17
DOCK4 dedicator of cytokinesis 4
DSCAM Down syndrome cell adhesion molecule
EPHA2 EPH receptor A2
ERCC6 excision repair cross-complementation group 6
FAAH fatty acid amide hydrolase
FAM131A family with sequence similarity 131, member A
FAM169A family with sequence similarity 169, member A
FBXO31 F-box protein 31
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLT4 fms-related tyrosine kinase 4
FUZ fuzzy planar cell polarity protein
GADD45G growth arrest and DNA-damage-inducible, gamma
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR3 G protein-coupled receptor 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRPR gastrin-releasing peptide receptor
GSTP1 glutathione S-transferase pi 1
GTF2I general transcription factor IIi
HAMP hepcidin antimicrobial peptide
HIRA histone cell cycle regulator
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA4 homeobox A4
HSPA2 heat shock 70kDa protein 2
IGSF1 immunoglobulin superfamily, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLHL25 kelch-like family member 25
LIME1 Lck interacting transmembrane adaptor 1
LMTK1 lemur tail kinase 1
LOC730101 uncharacterized LOC730101
LOXL3 lysyl oxidase-like 3
LPXN leupaxin
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MTA2 metastasis associated 1 family, member 2
MYO1E myosin IE
N4BP3 NEDD4 binding protein 3
NLGN1 neuroligin 1
NPTX1 neuronal pentraxin I
OLFML2A olfactomedin-like 2A
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE8B phosphodiesterase 8B
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHACTR4 phosphatase and actin regulator 4
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PTDSS2 phosphatidylserine synthase 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB5B RAB5B, member RAS oncogene family
RFTN1 raftlin, lipid raft linker 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF122 ring finger protein 122
RNF39 ring finger protein 39
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL10L ribosomal protein L10-like
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SEC14L5 SEC14-like 5 (S. cerevisiae)
SECTM1 secreted and transmembrane 1
SRD5A3 steroid 5 alpha-reductase 3
STK25 serine/threonine kinase 25
SUGP1 SURP and G patch domain containing 1
TEX30 testis expressed 30
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM25 tripartite motif containing 25
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VGF VGF nerve growth factor inducible
ZDHHC11 zinc finger, DHHC-type containing 11
ZFAND3 zinc finger, AN1-type domain 3
ZFHX2 zinc finger homeobox 2
ZNF136 zinc finger protein 136
ZNF248 zinc finger protein 248
ZNF446 zinc finger protein 446
ZNF675 zinc finger protein 675
ZNF862 zinc finger protein 862