| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the trazodone-7410 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| AIM1L | absent in melanoma 1-like |
| AJAP1 | adherens junctions associated protein 1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| AR | androgen receptor |
| ATP11A | ATPase, class VI, type 11A |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CD83 | CD83 molecule |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLDN17 | claudin 17 |
| CLMN | calmin (calponin-like, transmembrane) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 |
| DGCR6L | DiGeorge syndrome critical region gene 6-like |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DLG5 | discs, large homolog 5 (Drosophila) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DRD2 | dopamine receptor D2 |
| DST | dystonin |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EIF5 | eukaryotic translation initiation factor 5 |
| EPAS1 | endothelial PAS domain protein 1 |
| EPHA3 | EPH receptor A3 |
| ERCC2 | excision repair cross-complementation group 2 |
| FAM120C | family with sequence similarity 120C |
| FAM65A | family with sequence similarity 65, member A |
| FLT4 | fms-related tyrosine kinase 4 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GSTP1 | glutathione S-transferase pi 1 |
| HFE | hemochromatosis |
| HMG20B | high mobility group 20B |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IL16 | interleukin 16 |
| IL4R | interleukin 4 receptor |
| ING4 | inhibitor of growth family, member 4 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IRF1 | interferon regulatory factor 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRS2 | insulin receptor substrate 2 |
| KAZN | kazrin, periplakin interacting protein |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0125 | KIAA0125 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LIMK1 | LIM domain kinase 1 |
| LPIN1 | lipin 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MID1 | midline 1 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NF2 | neurofibromin 2 (merlin) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NLRX1 | NLR family member X1 |
| NOV | nephroblastoma overexpressed |
| PAX5 | paired box 5 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLIN2 | perilipin 2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTGES | prostaglandin E synthase |
| PXDC1 | PX domain containing 1 |
| RAP1GAP | RAP1 GTPase activating protein |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUFY3 | RUN and FYVE domain containing 3 |
| S100A8 | S100 calcium binding protein A8 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SNAI2 | snail family zinc finger 2 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPHK2 | sphingosine kinase 2 |
| SPRR3 | small proline-rich protein 3 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| STAB2 | stabilin 2 |
| STK4 | serine/threonine kinase 4 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TGM2 | transglutaminase 2 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TOP3A | topoisomerase (DNA) III alpha |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRIM62 | tripartite motif containing 62 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| TTC38 | tetratricopeptide repeat domain 38 |
| ZNF419 | zinc finger protein 419 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| ACYP2 | acylphosphatase 2, muscle type |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| AMOTL2 | angiomotin like 2 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| ATP11B | ATPase, class VI, type 11B |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CARD8 | caspase recruitment domain family, member 8 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CENPC | centromere protein C |
| CLDN9 | claudin 9 |
| COBL | cordon-bleu WH2 repeat protein |
| CTSK | cathepsin K |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DEAF1 | DEAF1 transcription factor |
| DUSP22 | dual specificity phosphatase 22 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ERCC5 | excision repair cross-complementation group 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM155B | family with sequence similarity 155, member B |
| FAM193A | family with sequence similarity 193, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| FZD4 | frizzled class receptor 4 |
| GAB2 | GRB2-associated binding protein 2 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| H2AFY2 | H2A histone family, member Y2 |
| HIST1H1D | histone cluster 1, H1d |
| HOXC10 | homeobox C10 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| JRKL | JRK-like |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KRT86 | keratin 86, type II |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LOC642236 | FSHD region gene 1 pseudogene |
| MBTD1 | mbt domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL16 | methyltransferase like 16 |
| MICALL2 | MICAL-like 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NES | nestin |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OXTR | oxytocin receptor |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| PDGFRL | platelet-derived growth factor receptor-like |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PRAF2 | PRA1 domain family, member 2 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB4B | RAB4B, member RAS oncogene family |
| RGS17 | regulator of G-protein signaling 17 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SERTAD3 | SERTA domain containing 3 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| TBC1D12 | TBC1 domain family, member 12 |
| TCTN1 | tectonic family member 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TRABD | TraB domain containing |
| TRIM5 | tripartite motif containing 5 |
| TULP4 | tubby like protein 4 |
| TWF2 | twinfilin actin binding protein 2 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF219 | zinc finger protein 219 |
| ZNF248 | zinc finger protein 248 |
| ZNF253 | zinc finger protein 253 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF365 | zinc finger protein 365 |
| ZNF468 | zinc finger protein 468 |
| ZNF816 | zinc finger protein 816 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
