| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the trazodone-7452 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| AK2 | adenylate kinase 2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| APOE | apolipoprotein E |
| ATN1 | atrophin 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C5AR2 | complement component 5a receptor 2 |
| CCDC134 | coiled-coil domain containing 134 |
| CCDC93 | coiled-coil domain containing 93 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) |
| CD80 | CD80 molecule |
| CDC14A | cell division cycle 14A |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDK13 | cyclin-dependent kinase 13 |
| CLTA | clathrin, light chain A |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DOK2 | docking protein 2, 56kDa |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EPHB2 | EPH receptor B2 |
| FGL2 | fibrinogen-like 2 |
| FLJ11292 | |
| GM2A | GM2 ganglioside activator |
| GPATCH4 | G patch domain containing 4 |
| GPC1 | glypican 1 |
| GSDMB | gasdermin B |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HDLBP | high density lipoprotein binding protein |
| IFT27 | intraflagellar transport 27 |
| IRF4 | interferon regulatory factor 4 |
| IRS2 | insulin receptor substrate 2 |
| JAK3 | Janus kinase 3 |
| JAM3 | junctional adhesion molecule 3 |
| KAT6A | K(lysine) acetyltransferase 6A |
| KDM6A | lysine (K)-specific demethylase 6A |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0930 | KIAA0930 |
| KIF1A | kinesin family member 1A |
| KLHL20 | kelch-like family member 20 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LENEP | lens epithelial protein |
| LIG3 | ligase III, DNA, ATP-dependent |
| MAP2 | microtubule-associated protein 2 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MED14 | mediator complex subunit 14 |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MMP11 | matrix metallopeptidase 11 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MVP | major vault protein |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCLN | nicalin |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NRF1 | nuclear respiratory factor 1 |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLAC4 | placenta-specific 4 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRPH | peripherin |
| RARA | retinoic acid receptor, alpha |
| RCAN3 | RCAN family member 3 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RGS12 | regulator of G-protein signaling 12 |
| RPL7 | ribosomal protein L7 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SAA4 | serum amyloid A4, constitutive |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC26A1 | solute carrier family 26 (anion exchanger), member 1 |
| SMAD4 | SMAD family member 4 |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SP100 | SP100 nuclear antigen |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST5 | suppression of tumorigenicity 5 |
| STAB2 | stabilin 2 |
| STXBP6 | syntaxin binding protein 6 (amisyn) |
| TAT | tyrosine aminotransferase |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM19 | transmembrane protein 19 |
| TMOD1 | tropomodulin 1 |
| TNS2 | tensin 2 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRH | thyrotropin-releasing hormone |
| USP34 | ubiquitin specific peptidase 34 |
| WDR78 | WD repeat domain 78 |
| WSCD1 | WSC domain containing 1 |
| Symbol | Name |
|---|---|
| ABCB7 | ATP-binding cassette, sub-family B (MDR/TAP), member 7 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ALAD | aminolevulinate dehydratase |
| AMOTL2 | angiomotin like 2 |
| ASL | argininosuccinate lyase |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATG2B | autophagy related 2B |
| BBC3 | BCL2 binding component 3 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC25 | coiled-coil domain containing 25 |
| CENPT | centromere protein T |
| CEP72 | centrosomal protein 72kDa |
| COPS7B | COP9 signalosome subunit 7B |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DENND1A | DENN/MADD domain containing 1A |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DSE | dermatan sulfate epimerase |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EPHA2 | EPH receptor A2 |
| FAM111A | family with sequence similarity 111, member A |
| FAM172A | family with sequence similarity 172, member A |
| FCHSD2 | FCH and double SH3 domains 2 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GSTT1 | glutathione S-transferase theta 1 |
| GTPBP2 | GTP binding protein 2 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H2AG | histone cluster 1, H2ag |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IFT81 | intraflagellar transport 81 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| ILKAP | integrin-linked kinase-associated serine/threonine phosphatase |
| JMJD1C | jumonji domain containing 1C |
| KLF11 | Kruppel-like factor 11 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRRC20 | leucine rich repeat containing 20 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| MANBA | mannosidase, beta A, lysosomal |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| METTL8 | methyltransferase like 8 |
| MGC12488 | |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MT1HL1 | metallothionein 1H-like 1 |
| MTMR11 | myotubularin related protein 11 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NHLRC2 | NHL repeat containing 2 |
| NLK | nemo-like kinase |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PANK4 | pantothenate kinase 4 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB33B | RAB33B, member RAS oncogene family |
| RASA2 | RAS p21 protein activator 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SDF2 | stromal cell-derived factor 2 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNRPC | small nuclear ribonucleoprotein polypeptide C |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TPCN1 | two pore segment channel 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM45 | tripartite motif containing 45 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTC17 | tetratricopeptide repeat domain 17 |
| TUBA3C | tubulin, alpha 3c |
| TWF2 | twinfilin actin binding protein 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VASP | vasodilator-stimulated phosphoprotein |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WFS1 | Wolfram syndrome 1 (wolframin) |
| WWC2 | WW and C2 domain containing 2 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF14 | zinc finger protein 14 |
| ZNF23 | zinc finger protein 23 |
