tremorine-1579 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the tremorine-1579 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRA3 adhesion G protein-coupled receptor A3
ADGRL1 adhesion G protein-coupled receptor L1
AKAP7 A kinase (PRKA) anchor protein 7
APAF1 apoptotic peptidase activating factor 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BFAR bifunctional apoptosis regulator
BMP7 bone morphogenetic protein 7
C2CD2L C2CD2-like
CCDC40 coiled-coil domain containing 40
CENPI centromere protein I
CHAF1A chromatin assembly factor 1, subunit A (p150)
COL8A2 collagen, type VIII, alpha 2
CRIPT cysteine-rich PDZ-binding protein
CS citrate synthase
CSF1 colony stimulating factor 1 (macrophage)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DPH2 DPH2 homolog (S. cerevisiae)
DRG2 developmentally regulated GTP binding protein 2
DST dystonin
DUS2 dihydrouridine synthase 2
EDC3 enhancer of mRNA decapping 3
ELAC2 elaC ribonuclease Z 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
F3 coagulation factor III (thromboplastin, tissue factor)
FANCF Fanconi anemia, complementation group F
FAS Fas cell surface death receptor
FCAR Fc fragment of IgA receptor
FKBP9 FK506 binding protein 9, 63 kDa
FLNC filamin C, gamma
GALR3 galanin receptor 3
GJB3 gap junction protein, beta 3, 31kDa
GPR32 G protein-coupled receptor 32
GRB7 growth factor receptor-bound protein 7
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
IL9R interleukin 9 receptor
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KDM5A lysine (K)-specific demethylase 5A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAPK3 mitogen-activated protein kinase 3
MKL1 megakaryoblastic leukemia (translocation) 1
MOCS2 molybdenum cofactor synthesis 2
MSH3 mutS homolog 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCR2 natural cytotoxicity triggering receptor 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OLFML2A olfactomedin-like 2A
OVGP1 oviductal glycoprotein 1, 120kDa
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLCB2 phospholipase C, beta 2
PLCG1 phospholipase C, gamma 1
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKCA protein kinase C, alpha
PRRC2B proline-rich coiled-coil 2B
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RIMS3 regulating synaptic membrane exocytosis 3
RLBP1 retinaldehyde binding protein 1
RPS11 ribosomal protein S11
S100A8 S100 calcium binding protein A8
SEPW1 selenoprotein W, 1
SH3BP2 SH3-domain binding protein 2
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNX27 sorting nexin family member 27
SOAT1 sterol O-acyltransferase 1
SPN sialophorin
SSH3 slingshot protein phosphatase 3
STAP2 signal transducing adaptor family member 2
SUGP1 SURP and G patch domain containing 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPMT thiopurine S-methyltransferase
TPT1 tumor protein, translationally-controlled 1
TRAPPC9 trafficking protein particle complex 9
TRIM21 tripartite motif containing 21
TRMT61A tRNA methyltransferase 61A
UBL3 ubiquitin-like 3
USF2 upstream transcription factor 2, c-fos interacting
VILL villin-like
ZC3H13 zinc finger CCCH-type containing 13
ZIM2 zinc finger, imprinted 2
ZNF701 zinc finger protein 701
ZNRF4 zinc and ring finger 4

decreased expression

Symbol Name
ACP2 acid phosphatase 2, lysosomal
AIDA axin interactor, dorsalization associated
ALPK1 alpha-kinase 1
ANKHD1 ankyrin repeat and KH domain containing 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ASB8 ankyrin repeat and SOCS box containing 8
ATAD5 ATPase family, AAA domain containing 5
ATF3 activating transcription factor 3
ATP11B ATPase, class VI, type 11B
BRPF1 bromodomain and PHD finger containing, 1
CCDC47 coiled-coil domain containing 47
CCL2 chemokine (C-C motif) ligand 2
CDC37 cell division cycle 37
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK8 cyclin-dependent kinase 8
CEP85 centrosomal protein 85kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN15 claudin 15
CRTAP cartilage associated protein
CRYZL1 crystallin, zeta (quinone reductase)-like 1
DCTN4 dynactin 4 (p62)
DMXL1 Dmx-like 1
DNA2 DNA replication helicase/nuclease 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPYD dihydropyrimidine dehydrogenase
ECHDC2 enoyl CoA hydratase domain containing 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EMD emerin
ERCC3 excision repair cross-complementation group 3
FAM222B family with sequence similarity 222, member B
GAB2 GRB2-associated binding protein 2
GIN1 gypsy retrotransposon integrase 1
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPS1 G protein pathway suppressor 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A2 general transcription factor IIA, 2, 12kDa
HAL histidine ammonia-lyase
HDAC4 histone deacetylase 4
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
IL10RB interleukin 10 receptor, beta
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
IMPACT impact RWD domain protein
IP6K1 inositol hexakisphosphate kinase 1
KCTD15 potassium channel tetramerization domain containing 15
KPNA4 karyopherin alpha 4 (importin alpha 3)
LACTB2 lactamase, beta 2
LEMD3 LEM domain containing 3
LINC00341 long intergenic non-protein coding RNA 341
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MANBA mannosidase, beta A, lysosomal
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK12 mitogen-activated protein kinase 12
MED15 mediator complex subunit 15
MED4 mediator complex subunit 4
MGAM maltase-glucoamylase
MIS12 MIS12 kinetochore complex component
MOAP1 modulator of apoptosis 1
MUTYH mutY homolog
NADSYN1 NAD synthetase 1
NSUN3 NOP2/Sun domain family, member 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAQR3 progestin and adipoQ receptor family member III
PELI2 pellino E3 ubiquitin protein ligase family member 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGS1 phosphatidylglycerophosphate synthase 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PSAT1 phosphoserine aminotransferase 1
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RPAP1 RNA polymerase II associated protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SDF2L1 stromal cell-derived factor 2-like 1
SERINC1 serine incorporator 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC25A40 solute carrier family 25, member 40
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNAP29 synaptosomal-associated protein, 29kDa
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STK39 serine threonine kinase 39
SUN2 Sad1 and UNC84 domain containing 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMBIM4 transmembrane BAX inhibitor motif containing 4
TOMM34 translocase of outer mitochondrial membrane 34
TOPBP1 topoisomerase (DNA) II binding protein 1
TRAPPC11 trafficking protein particle complex 11
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TTC1 tetratricopeptide repeat domain 1
TTC4 tetratricopeptide repeat domain 4
TUBA1A tubulin, alpha 1a
UBE3C ubiquitin protein ligase E3C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF212 zinc finger protein 212
ZNF267 zinc finger protein 267
ZNF84 zinc finger protein 84