tremorine-3196 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the tremorine-3196 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADAM22 ADAM metallopeptidase domain 22
ADORA1 adenosine A1 receptor
ALCAM activated leukocyte cell adhesion molecule
ANAPC13 anaphase promoting complex subunit 13
ANKRD53 ankyrin repeat domain 53
ARID4B AT rich interactive domain 4B (RBP1-like)
ATF5 activating transcription factor 5
ATF7IP activating transcription factor 7 interacting protein
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBS9 Bardet-Biedl syndrome 9
BTF3P11 basic transcription factor 3 pseudogene 11
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CDADC1 cytidine and dCMP deaminase domain containing 1
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLDN11 claudin 11
COL21A1 collagen, type XXI, alpha 1
CTRL chymotrypsin-like
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLX4 distal-less homeobox 4
DOPEY2 dopey family member 2
DUSP9 dual specificity phosphatase 9
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FASLG Fas ligand (TNF superfamily, member 6)
FKBP10 FK506 binding protein 10, 65 kDa
FOSL2 FOS-like antigen 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUT2 fucosyltransferase 2 (secretor status included)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNRHR gonadotropin-releasing hormone receptor
GPM6B glycoprotein M6B
GPR21 G protein-coupled receptor 21
GRM3 glutamate receptor, metabotropic 3
GSTM5 glutathione S-transferase mu 5
HAP1 huntingtin-associated protein 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
ICAM1 intercellular adhesion molecule 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFFO1 intermediate filament family orphan 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IMPG2 interphotoreceptor matrix proteoglycan 2
IRF6 interferon regulatory factor 6
JRK Jrk homolog (mouse)
KRT17 keratin 17, type I
LARP7 La ribonucleoprotein domain family, member 7
LY96 lymphocyte antigen 96
MAP1B microtubule-associated protein 1B
MLANA melan-A
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MSR1 macrophage scavenger receptor 1
MST1L macrophage stimulating 1-like
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NMT2 N-myristoyltransferase 2
NRG1 neuregulin 1
OGFR opioid growth factor receptor
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PAX2 paired box 2
PCDH17 protocadherin 17
PDLIM5 PDZ and LIM domain 5
PER2 period circadian clock 2
PHC3 polyhomeotic homolog 3 (Drosophila)
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLAC4 placenta-specific 4
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PPP5C protein phosphatase 5, catalytic subunit
PRICKLE3 prickle homolog 3 (Drosophila)
RBM48 RNA binding motif protein 48
RGS5 regulator of G-protein signaling 5
RIMS3 regulating synaptic membrane exocytosis 3
RND1 Rho family GTPase 1
RPA4 replication protein A4, 30kDa
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNX1 runt-related transcription factor 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC25A30 solute carrier family 25, member 30
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLURP1 secreted LY6/PLAUR domain containing 1
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPTBN2 spectrin, beta, non-erythrocytic 2
SSTR5 somatostatin receptor 5
STXBP5L syntaxin binding protein 5-like
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAS2R10 taste receptor, type 2, member 10
TCF20 transcription factor 20 (AR1)
TLE4 transducin-like enhancer of split 4
TRIM21 tripartite motif containing 21
VCAN versican
VWA5A von Willebrand factor A domain containing 5A
WDR4 WD repeat domain 4
ZBTB7A zinc finger and BTB domain containing 7A
ZIC3 Zic family member 3
ZNF197 zinc finger protein 197

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACAD10 acyl-CoA dehydrogenase family, member 10
ACSF2 acyl-CoA synthetase family member 2
ADGRG2 adhesion G protein-coupled receptor G2
AKAP7 A kinase (PRKA) anchor protein 7
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
C8ORF60 chromosome 8 open reading frame 60
CAPN15 calpain 15
CCDC69 coiled-coil domain containing 69
CENPT centromere protein T
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEC cell death-inducing DFFA-like effector c
CORT cortistatin
CRY2 cryptochrome circadian clock 2
CST6 cystatin E/M
CTC1 CTS telomere maintenance complex component 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGAT1 diacylglycerol O-acyltransferase 1
DMTN dematin actin binding protein
DNAH17 dynein, axonemal, heavy chain 17
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
DYSF dysferlin
EGFL7 EGF-like-domain, multiple 7
ELOVL4 ELOVL fatty acid elongase 4
ELP6 elongator acetyltransferase complex subunit 6
EMID1 EMI domain containing 1
EPHA2 EPH receptor A2
EXOC6B exocyst complex component 6B
FAM86C1 family with sequence similarity 86, member C1
FLCN folliculin
GAMT guanidinoacetate N-methyltransferase
GEMIN8 gem (nuclear organelle) associated protein 8
GFOD1 glucose-fructose oxidoreductase domain containing 1
GMIP GEM interacting protein
GMPR guanosine monophosphate reductase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
INCENP inner centromere protein antigens 135/155kDa
KCTD20 potassium channel tetramerization domain containing 20
KIAA1456 KIAA1456
KIF13A kinesin family member 13A
KLHL26 kelch-like family member 26
KLK5 kallikrein-related peptidase 5
KRT13 keratin 13, type I
LDHB lactate dehydrogenase B
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPAR4 lysophosphatidic acid receptor 4
LYZ lysozyme
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP9 microtubule-associated protein 9
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
NLRX1 NLR family member X1
NNAT neuronatin
NRGN neurogranin (protein kinase C substrate, RC3)
NRSN2 neurensin 2
OLFML2A olfactomedin-like 2A
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRSS22 protease, serine, 22
QSER1 glutamine and serine rich 1
RIN2 Ras and Rab interactor 2
SDC3 syndecan 3
SIK1 salt-inducible kinase 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SOX3 SRY (sex determining region Y)-box 3
SRGN serglycin
STARD3 StAR-related lipid transfer (START) domain containing 3
STBD1 starch binding domain 1
TMEM120B transmembrane protein 120B
TMEM121 transmembrane protein 121
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP20 ubiquitin specific peptidase 20
VEGFB vascular endothelial growth factor B
VEZT vezatin, adherens junctions transmembrane protein
WDR25 WD repeat domain 25
WDR62 WD repeat domain 62
ZBTB48 zinc finger and BTB domain containing 48
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF134 zinc finger protein 134
ZNF205 zinc finger protein 205
ZNF350 zinc finger protein 350
ZNF446 zinc finger protein 446
ZNF74 zinc finger protein 74