| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tretinoin-1049 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACOX3 | acyl-CoA oxidase 3, pristanoyl |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AOX1 | aldehyde oxidase 1 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATXN1 | ataxin 1 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BDKRB2 | bradykinin receptor B2 |
| BTG2 | BTG family, member 2 |
| C1ORF112 | chromosome 1 open reading frame 112 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CDH5 | cadherin 5, type 2 (vascular endothelium) |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CLMN | calmin (calponin-like, transmembrane) |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CSTA | cystatin A (stefin A) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DOPEY2 | dopey family member 2 |
| DUSP4 | dual specificity phosphatase 4 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EPAS1 | endothelial PAS domain protein 1 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| FAM174B | family with sequence similarity 174, member B |
| FOXO3 | forkhead box O3 |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| FZD5 | frizzled class receptor 5 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HHEX | hematopoietically expressed homeobox |
| HOXA1 | homeobox A1 |
| HOXA5 | homeobox A5 |
| HOXB2 | homeobox B2 |
| HOXC13 | homeobox C13 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IRS2 | insulin receptor substrate 2 |
| ITCH | itchy E3 ubiquitin protein ligase |
| KAZN | kazrin, periplakin interacting protein |
| KIAA0125 | KIAA0125 |
| KLK6 | kallikrein-related peptidase 6 |
| LAMA3 | laminin, alpha 3 |
| LDLRAP1 | low density lipoprotein receptor adaptor protein 1 |
| METTL18 | methyltransferase like 18 |
| METTL5 | methyltransferase like 5 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| NANS | N-acetylneuraminic acid synthase |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| OPN3 | opsin 3 |
| OSMR | oncostatin M receptor |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLA2G10 | phospholipase A2, group X |
| PRKCD | protein kinase C, delta |
| PRKCH | protein kinase C, eta |
| PRMT2IP | PRMT2 interacting protein |
| PRR5 | proline rich 5 (renal) |
| PTGES | prostaglandin E synthase |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RAP1GAP | RAP1 GTPase activating protein |
| RET | ret proto-oncogene |
| RGS16 | regulator of G-protein signaling 16 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| S100P | S100 calcium binding protein P |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SKAP2 | src kinase associated phosphoprotein 2 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SMAD3 | SMAD family member 3 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMPRSS2 | transmembrane protease, serine 2 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRAF4 | TNF receptor-associated factor 4 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIM2 | tripartite motif containing 2 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN5 | tetraspanin 5 |
| TXNL4B | thioredoxin-like 4B |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADGRL2 | adhesion G protein-coupled receptor L2 |
| AGO1 | argonaute RISC catalytic component 1 |
| AIM1 | absent in melanoma 1 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARHGAP17 | Rho GTPase activating protein 17 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARL4A | ADP-ribosylation factor-like 4A |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATG9A | autophagy related 9A |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CCDC109B | coiled-coil domain containing 109B |
| CCDC92 | coiled-coil domain containing 92 |
| CCS | copper chaperone for superoxide dismutase |
| CDC73 | cell division cycle 73 |
| COQ6 | coenzyme Q6 monooxygenase |
| CRY1 | cryptochrome circadian clock 1 |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DUSP14 | dual specificity phosphatase 14 |
| DVL1 | dishevelled segment polarity protein 1 |
| EGR3 | early growth response 3 |
| EPPK1 | epiplakin 1 |
| ERCC3 | excision repair cross-complementation group 3 |
| EVL | Enah/Vasp-like |
| FBXO5 | F-box protein 5 |
| FOXJ2 | forkhead box J2 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GHR | growth hormone receptor |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GRAMD3 | GRAM domain containing 3 |
| GRB14 | growth factor receptor-bound protein 14 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HCFC2 | host cell factor C2 |
| HJURP | Holliday junction recognition protein |
| HMG20A | high mobility group 20A |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
| IFT46 | intraflagellar transport 46 |
| IGFLR1 | IGF-like family receptor 1 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KCTD9 | potassium channel tetramerization domain containing 9 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAP7D1 | MAP7 domain containing 1 |
| MED22 | mediator complex subunit 22 |
| MED24 | mediator complex subunit 24 |
| METTL16 | methyltransferase like 16 |
| MISP | mitotic spindle positioning |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MPDZ | multiple PDZ domain protein |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 |
| NXN | nucleoredoxin |
| OSR2 | odd-skipped related transciption factor 2 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| PODXL | podocalyxin-like |
| PRPF39 | pre-mRNA processing factor 39 |
| PRR15L | proline rich 15-like |
| PRR7 | proline rich 7 (synaptic) |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RBBP8 | retinoblastoma binding protein 8 |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RHOB | ras homolog family member B |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMAD7 | SMAD family member 7 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SNIP1 | Smad nuclear interacting protein 1 |
| SSBP2 | single-stranded DNA binding protein 2 |
| SSFA2 | sperm specific antigen 2 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STXBP1 | syntaxin binding protein 1 |
| TBC1D12 | TBC1 domain family, member 12 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TES | testin LIM domain protein |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TOLLIP | toll interacting protein |
| TP53I3 | tumor protein p53 inducible protein 3 |
| TRAF5 | TNF receptor-associated factor 5 |
| UNC13B | unc-13 homolog B (C. elegans) |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| WDR44 | WD repeat domain 44 |
| WDR47 | WD repeat domain 47 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZFP36 | ZFP36 ring finger protein |
| ZMAT5 | zinc finger, matrin-type 5 |
