tretinoin-1152 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the tretinoin-1152 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADD3 adducin 3 (gamma)
AIM2 absent in melanoma 2
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANGPTL4 angiopoietin-like 4
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASRGL1 asparaginase like 1
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BCL6 B-cell CLL/lymphoma 6
C1ORF106 chromosome 1 open reading frame 106
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCR1 chemokine (C-C motif) receptor 1
CD1D CD1d molecule
CD300A CD300a molecule
CD38 CD38 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFP complement factor properdin
COL4A2 collagen, type IV, alpha 2
CPD carboxypeptidase D
CREM cAMP responsive element modulator
CXCR4 chemokine (C-X-C motif) receptor 4
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EFNB2 ephrin-B2
ENDOD1 endonuclease domain containing 1
EXPH5 exophilin 5
FAM134B family with sequence similarity 134, member B
FAM13A family with sequence similarity 13, member A
FBP1 fructose-1,6-bisphosphatase 1
FCMR Fc fragment of IgM receptor
FGR FGR proto-oncogene, Src family tyrosine kinase
FLOT1 flotillin 1
G0S2 G0/G1 switch 2
GAS7 growth arrest-specific 7
GATA6 GATA binding protein 6
HBEGF heparin-binding EGF-like growth factor
HOXA1 homeobox A1
HOXA5 homeobox A5
HPD 4-hydroxyphenylpyruvate dioxygenase
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI30 interferon, gamma-inducible protein 30
ITGA6 integrin, alpha 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB5 integrin, beta 5
ITGB7 integrin, beta 7
KCTD12 potassium channel tetramerization domain containing 12
LAMB3 laminin, beta 3
LIF leukemia inhibitory factor
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN1A1 mannosidase, alpha, class 1A, member 1
MLXIPL MLX interacting protein-like
MYBPH myosin binding protein H
NCF1C neutrophil cytosolic factor 1C pseudogene
NCOA3 nuclear receptor coactivator 3
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOTCH2 notch 2
NRIP1 nuclear receptor interacting protein 1
NTSR1 neurotensin receptor 1 (high affinity)
OLAH oleoyl-ACP hydrolase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PALLD palladin, cytoskeletal associated protein
PDLIM5 PDZ and LIM domain 5
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLEK pleckstrin
PLK3 polo-like kinase 3
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POR P450 (cytochrome) oxidoreductase
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRKCH protein kinase C, eta
PSAP prosaposin
PTGES prostaglandin E synthase
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RCAN1 regulator of calcineurin 1
RHOBTB3 Rho-related BTB domain containing 3
RHOQ ras homolog family member Q
S100A9 S100 calcium binding protein A9
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SLA Src-like-adaptor
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SMAD3 SMAD family member 3
SMOX spermine oxidase
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
TBL2 transducin (beta)-like 2
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR5 toll-like receptor 5
UPB1 ureidopropionase, beta
UPP1 uridine phosphorylase 1
VSIG4 V-set and immunoglobulin domain containing 4

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ANKRD28 ankyrin repeat domain 28
ANKRD55 ankyrin repeat domain 55
ANO10 anoctamin 10
ANXA3 annexin A3
BATF basic leucine zipper transcription factor, ATF-like
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BYSL bystin-like
C10ORF2 chromosome 10 open reading frame 2
C16ORF59 chromosome 16 open reading frame 59
C1ORF109 chromosome 1 open reading frame 109
C5ORF30 chromosome 5 open reading frame 30
CA2 carbonic anhydrase II
CBR1 carbonyl reductase 1
CCDC109B coiled-coil domain containing 109B
CCDC86 coiled-coil domain containing 86
CD3EAP CD3e molecule, epsilon associated protein
CD69 CD69 molecule
CDR2 cerebellar degeneration-related protein 2, 62kDa
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CINP cyclin-dependent kinase 2 interacting protein
CLEC5A C-type lectin domain family 5, member A
CTSG cathepsin G
CUTC cutC copper transporter
DEAF1 DEAF1 transcription factor
DNAAF2 dynein, axonemal, assembly factor 2
DPH2 DPH2 homolog (S. cerevisiae)
EGLN2 egl-9 family hypoxia-inducible factor 2
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
F3 coagulation factor III (thromboplastin, tissue factor)
FKBP5 FK506 binding protein 5
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HOMER1 homer scaffolding protein 1
HOPX HOP homeobox
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCTD15 potassium channel tetramerization domain containing 15
LAMP5 lysosomal-associated membrane protein family, member 5
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MGAM maltase-glucoamylase
MRPS2 mitochondrial ribosomal protein S2
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NIP7 NIP7, nucleolar pre-rRNA processing protein
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NTHL1 nth endonuclease III-like 1 (E. coli)
OPN3 opsin 3
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PFAS phosphoribosylformylglycinamidine synthase
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIEZO1 piezo-type mechanosensitive ion channel component 1
PLCB4 phospholipase C, beta 4
PNMA1 paraneoplastic Ma antigen 1
PPAN peter pan homolog (Drosophila)
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRKX protein kinase, X-linked
PRMT3 protein arginine methyltransferase 3
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTX3 pentraxin 3, long
PUS7 pseudouridylate synthase 7 (putative)
RFTN1 raftlin, lipid raft linker 1
RPP40 ribonuclease P/MRP 40kDa subunit
RRP1 ribosomal RNA processing 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SACS sacsin molecular chaperone
SDCCAG3 serologically defined colon cancer antigen 3
SETD6 SET domain containing 6
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC35F2 solute carrier family 35, member F2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
TERT telomerase reverse transcriptase
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM62 transmembrane protein 62
TOMM34 translocase of outer mitochondrial membrane 34
TRAC T cell receptor alpha constant
TUBA3C tubulin, alpha 3c
TWISTNB TWIST neighbor
UBIAD1 UbiA prenyltransferase domain containing 1
UNG uracil-DNA glycosylase
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VCAN versican
WDR3 WD repeat domain 3
WDR46 WD repeat domain 46
WNT10B wingless-type MMTV integration site family, member 10B
WT1 Wilms tumor 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF692 zinc finger protein 692