tretinoin-1211 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the tretinoin-1211 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADM adrenomedullin
AHI1 Abelson helper integration site 1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
APC adenomatous polyposis coli
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
BCL2L1 BCL2-like 1
C10ORF10 chromosome 10 open reading frame 10
C1QTNF3 C1q and tumor necrosis factor related protein 3
C4ORF29 chromosome 4 open reading frame 29
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCDC186 coiled-coil domain containing 186
CDC42 cell division cycle 42
CFH complement factor H
CHMP6 charged multivesicular body protein 6
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CPNE7 copine VII
CRY2 cryptochrome circadian clock 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHODH dihydroorotate dehydrogenase (quinone)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EGR1 early growth response 1
ELAC2 elaC ribonuclease Z 2
ESRRA estrogen-related receptor alpha
EWSR1 EWS RNA-binding protein 1
FAM168A family with sequence similarity 168, member A
FBXO2 F-box protein 2
GIF gastric intrinsic factor (vitamin B synthesis)
GLP1R glucagon-like peptide 1 receptor
GPATCH2L G patch domain containing 2-like
GPRC5D G protein-coupled receptor, class C, group 5, member D
HIST1H1D histone cluster 1, H1d
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
IFNA17 interferon, alpha 17
IL1B interleukin 1, beta
ITGB4 integrin, beta 4
KITLG KIT ligand
LRRK1 leucine-rich repeat kinase 1
MECP2 methyl CpG binding protein 2
MID1 midline 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NELL2 NEL-like 2 (chicken)
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NPAS2 neuronal PAS domain protein 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCNXL2 pecanex-like 2 (Drosophila)
PDGFB platelet-derived growth factor beta polypeptide
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCG1 phospholipase C, gamma 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRF1 perforin 1 (pore forming protein)
PRR4 proline rich 4 (lacrimal)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB11B RAB11B, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBM19 RNA binding motif protein 19
RPS9 ribosomal protein S9
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC39A9 solute carrier family 39, member 9
SMG5 SMG5 nonsense mediated mRNA decay factor
SMYD5 SMYD family member 5
SOX12 SRY (sex determining region Y)-box 12
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPTBN1 spectrin, beta, non-erythrocytic 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX5 syntaxin 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYNGR1 synaptogyrin 1
THBD thrombomodulin
TLE4 transducin-like enhancer of split 4
TMEM209 transmembrane protein 209
TMEM259 transmembrane protein 259
TMEM53 transmembrane protein 53
TUSC2 tumor suppressor candidate 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TWISTNB TWIST neighbor
TXK TXK tyrosine kinase
UBE3A ubiquitin protein ligase E3A
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VEGFA vascular endothelial growth factor A
VGLL3 vestigial-like family member 3
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
YY2 YY2 transcription factor
ZNF141 zinc finger protein 141
ZNF277 zinc finger protein 277
ZNF287 zinc finger protein 287

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACBD4 acyl-CoA binding domain containing 4
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKRD36 ankyrin repeat domain 36
APH1B APH1B gamma secretase subunit
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
BCAS3 breast carcinoma amplified sequence 3
BMP4 bone morphogenetic protein 4
C16ORF45 chromosome 16 open reading frame 45
C16ORF59 chromosome 16 open reading frame 59
C19ORF40 chromosome 19 open reading frame 40
C1ORF115 chromosome 1 open reading frame 115
CAPN5 calpain 5
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLUH clustered mitochondria (cluA/CLU1) homolog
CYB5R2 cytochrome b5 reductase 2
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DENND4B DENN/MADD domain containing 4B
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DTX2 deltex 2, E3 ubiquitin ligase
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
E4F1 E4F transcription factor 1
EFNA3 ephrin-A3
EGF epidermal growth factor
ERCC2 excision repair cross-complementation group 2
FAM155A family with sequence similarity 155, member A
FGF1 fibroblast growth factor 1 (acidic)
FHOD1 formin homology 2 domain containing 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC4 histone deacetylase 4
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
IFI27 interferon, alpha-inducible protein 27
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IL17RB interleukin 17 receptor B
IL32 interleukin 32
JAM3 junctional adhesion molecule 3
KRT37 keratin 37, type I
LARP6 La ribonucleoprotein domain family, member 6
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP5L low density lipoprotein receptor-related protein 5-like
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYPD3 LY6/PLAUR domain containing 3
MCTP1 multiple C2 domains, transmembrane 1
MGC12488
MNX1 motor neuron and pancreas homeobox 1
MYLIP myosin regulatory light chain interacting protein
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NDP Norrie disease (pseudoglioma)
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NPDC1 neural proliferation, differentiation and control, 1
NYNRIN NYN domain and retroviral integrase containing
OLFML2A olfactomedin-like 2A
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PC pyruvate carboxylase
PCBP4 poly(rC) binding protein 4
PCOLCE procollagen C-endopeptidase enhancer
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POMT2 protein-O-mannosyltransferase 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRR14L proline rich 14-like
PYCRL pyrroline-5-carboxylate reductase-like
RBM38 RNA binding motif protein 38
RNF122 ring finger protein 122
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDC3 syndecan 3
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH3GL2 SH3-domain GRB2-like 2
SLC12A9 solute carrier family 12, member 9
SLC22A18 solute carrier family 22, member 18
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNPH syntaphilin
SPATA2L spermatogenesis associated 2-like
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TIMP4 TIMP metallopeptidase inhibitor 4
TM7SF2 transmembrane 7 superfamily member 2
TMEM40 transmembrane protein 40
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTLL7 tubulin tyrosine ligase-like family member 7
UNKL unkempt family zinc finger-like
USP20 ubiquitin specific peptidase 20
USP27X ubiquitin specific peptidase 27, X-linked
USP6 ubiquitin specific peptidase 6
VASP vasodilator-stimulated phosphoprotein
WDR91 WD repeat domain 91
WFS1 Wolfram syndrome 1 (wolframin)
XAB2 XPA binding protein 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBED1 zinc finger, BED-type containing 1
ZNF473 zinc finger protein 473
ZNF696 zinc finger protein 696